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Laparoscopic Intersphincteric Resection for Low Rectal Cancer

World Journal of Surgery volume 35, pages 2811–2817 (2011)Cite this article

Abstract

Background

Laparoscopic intersphincteric resection (ISR) after neoadjuvant chemoradiation is helpful in the management of patients with low rectal cancer. With the advent of this technique, the need for performance of abdominoperineal resection seems to have decreased in patients with very low rectal tumors. The aim of the present study was to evaluate the feasibility, the functional outcome, and the short-term oncologic outcomes of laparoscopic ISR for low rectal adenocarcinoma at our institution.

Methods

We retrospectively reviewed the data of 111 consecutive patients who underwent laparoscopic ISR for low rectal adenocarcinoma between July 2005 and December 2009. Demographic status, surgical outcomes, functional outcome data, and oncologic outcome data were collected.

Results

The mean distance of the tumor from the anal verge was 3.4 cm (range: 1–5 cm). The mean operative time was 214.7 min (range, 150–450 min). The mean distal resection margin was 1.3 ± 1.1 cm. Morbidity occurred in 24 patients (21.6%), including anastomotic leakage in 2 patients (1.8%). The mean Wexner continence score after stoma repair was 7.5 ± 2.7 (range: 2 ~ 19), and 9.8 in total ISR, 7.3 in partial ISR (P = 0.071). The 3-year overall survival rate was 92.8%, and the 3-year disease-free survival rate was 73.0%. Local recurrence was noted in 6 of the 111 patients with TNM stage I to III (5.4%). The patients with lesions at 2 cm to the dentate line had a 7.07-fold greater risk of local recurrence, including a 13.42-fold greater risk of lateral pelvic wall recurrence and perineal recurrence (95% Confidence interval [CI], 1.141–158.006; P = 0.009) than in those who had lesions more than 2 cm from the anal verge (95% CI, 1.290–38.832; P = 0.011).

Conclusions

Laparoscopic ISR after neoadjuvant chemoradiation can be recommended as a technically feasible, minimally invasive, and a sphincter-saving procedure with acceptable functional and short-term oncologic outcomes in patients with very low rectal cancer.

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Conflicts of interest

The authors declare no conflict of interest.

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Affiliations

  1. Department of Colon and Rectal Surgery, Chonnam National University Hwasun Hospital, 160 ilsim-ri, Hwasun-eup, Hwasun-gun, Jeollanamdo, 519-809, Korea

    Sang Woo Lim, Jung Wook Huh, Young Jin Kim & Hyeong Rok Kim

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  1. Sang Woo Lim
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  2. Jung Wook Huh
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Correspondence to Hyeong Rok Kim.

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Lim, S.W., Huh, J.W., Kim, Y.J. et al. Laparoscopic Intersphincteric Resection for Low Rectal Cancer. World J Surg 35, 2811–2817 (2011). https://doi.org/10.1007/s00268-011-1277-2

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Keywords

  • Circumferential Resection Margin
  • Preoperative Chemoradiation
  • Distal Resection Margin
  • Wexner Score
  • Intersphincteric Groove