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Diagnostic Value of Measuring Liver Volume for Detecting Occult Hepatic Metastases from Colorectal or Gastric Cancer

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Abstract

Some studies have shown reduced portal blood flow in patients with occult hepatic metastases, which may lead to decreased liver volume. A retrospective study was conducted in patients undergoing curative resection for colorectal (n = 63) or gastric (n = 52) cancer. The ratio of the preoperative computed tomography (CT)-estimated liver volume to the standard liver volume (CV/SV ratio) was calculated. The mean ± SD CT-estimated liver volume was 858 ±109 in 14 patients who subsequently developed hepatic metastases and 1173 ± 230 ml in 101 patients without metastases (p < 0.0001). The CV/SV ratio was smaller in patients with metachronous hepatic metastases than in those without (0.78 ± 0.08 vs. 1.02 + 0.13; p < 0.0001). The results suggest that the liver with occult metastases decreases in size before metastases develop that are detectable using conventional imaging techniques. The CV/SV ratio may be of value in detecting occult hepatic metastases from colorectal and gastric cancer.

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Authors and Affiliations

  1. First Department of Surgery, Tokyo Teishin Hospital, 2-14-23 Fujimi, Chiyoda-ku, Tokyo, 102-8798, Japan

    Takeaki Ishizawa M.D., Tetsuhisa Yamamoto M.D., Ph.D., Koichiro Nishida M.D., Hajime Tsukui M.D. & Takayoshi Sekikawa M.D., Ph.D.

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  1. Takeaki Ishizawa M.D.
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  2. Tetsuhisa Yamamoto M.D., Ph.D.
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  3. Koichiro Nishida M.D.
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  4. Hajime Tsukui M.D.
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  5. Takayoshi Sekikawa M.D., Ph.D.
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Correspondence to Tetsuhisa Yamamoto M.D., Ph.D..

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Ishizawa, T., Yamamoto, T., Nishida, K. et al. Diagnostic Value of Measuring Liver Volume for Detecting Occult Hepatic Metastases from Colorectal or Gastric Cancer. World J. Surg. 29, 719–722 (2005). https://doi.org/10.1007/s00268-005-7888-8

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  • DOI: https://doi.org/10.1007/s00268-005-7888-8

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