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Hand-assisted Laparoscopic Surgery with a Pfannenstiel Incision in β-Thalassemia Patients: Initial Experience

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Abstract

Introduction

β-Thalassemia patients have splenomegaly significant enough to require splenectomy; furthermore, these patients also often require concurrent procedures.

Methods

Between January and October 2005, seven patients with β-thalassemia underwent hand-assisted laparoscopic splenectomy with cholecystectomy, appendectomy, and liver biopsy with the hand-port device introduced through a Pfannenstiel incision.

Results

The median age of the patients was 28 years, and the median spleen length was 23 cm. The median operating time was 210 minutes; there were no conversions to an open procedure; and the median spleen weight was 1072 g. One major postoperative complication occurred. The median hospital stay was 6 days.

Conclusions

The proposed hand-assisted laparoscopic approach is safe and feasible. It provides a minimally invasive alternative that may become the treatment of choice in β-thalassemia patients who require concurrent operations.

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References

  1. Weatherall D, Provan A. Red cell. I. Inherited anaemias. Lancet 2000;355:1169–1175

    Article  PubMed  CAS  Google Scholar 

  2. Katz R, Goldfarb A, Muggia M, et al. Unique features of laparoscopic cholecystectomy in beta thalassemia patients. Surg Laparosc Endosc Percutan Tech 2003;13:318–321

    Article  PubMed  Google Scholar 

  3. Rosen M, Brody F, Walsh R, et al. Outcome of laparoscopic splenectomy based on hematologic indication. Surg Endosc 2002;16:272–279

    Article  PubMed  CAS  Google Scholar 

  4. Decker G, Millat B, Guillon F, et al. Laparoscopic splenectomy for benign and malignant hematologic diseases: 35 consecutive patients. World J Surg 1998;22:1–7

    Article  Google Scholar 

  5. Ailawadi G, Yahanda A, Dimick J, et al. Hand-assisted laparoscopic splenectomy in patients with splenomegaly or prior upper abdominal operation. Surgery 2002;132:689–696

    Article  PubMed  Google Scholar 

  6. Patel A, Parker J, Wallwork B, et al. Massive splenomegaly is associated with significant morbidity after laparoscopic splenectomy. Ann Surg 2003;238:235–240

    Article  PubMed  Google Scholar 

  7. Rosen M, Brody F, Walsh R, et al. Hand-assisted laparoscopic splenectomy vs conventional laparoscopic splenectomy in cases of splenomegaly. Arch Surg 2002;137:1348–1352

    Article  PubMed  Google Scholar 

  8. Laopodis V, Kritikos E, Rizzoti L, et al. Laparoscopic splenectomy in beta-thalassemia major patients: advantages and disadvantages. Surg Endosc 1998;12:944–947

    Article  PubMed  CAS  Google Scholar 

  9. Maartense S, Bemelman W, Gerritsen van der hoop A, et al. Hand-assisted laparoscopic surgery (hals): a report of 150 procedures. Surg Endosc 2004;18:397–401

    Article  PubMed  CAS  Google Scholar 

  10. Konstadoulakis M, Antonakis P, Katatzikos G, et al. Intraoperative findings and postoperative complications in laparoscopic cholecystectomy: the greek experience with 5539 patients in a single unit. J Laparoend Adv Surg Tech 2004;14:31–36

    Article  Google Scholar 

  11. Dindo D, Demartines N, Clavien P. Classification of surgical complications. Ann Surg 2004;240:205–213

    Article  PubMed  Google Scholar 

  12. Heniford B, Park A, Walsh R, et al. Laparoscopic splenectomy in patients with normal-sized spleens versus splenomegaly: does size matter? Am Surg 2001;67:854–857

    PubMed  CAS  Google Scholar 

  13. Kercher K, Matthews B, Walsh R, et al. Laparoscopic splenectomy for massive splenomegaly. Am J Surg 2002;183:192–196

    Article  PubMed  Google Scholar 

  14. Targarona E, Balague C, Cerdan G, et al. Hand assisted laparoscopic splenectomy (HALS) in cases of splenomegaly: a comparison analysis with conventional laparoscopic splenectomy. Surg Endosc 2002;16:426–430

    Article  PubMed  CAS  Google Scholar 

  15. Green N. Yersinia infections in patients with homozygous beta-thalassemia associated with iron overload and its treatment. Pediatr Hematol Oncol 1992;9:247–254

    PubMed  CAS  Google Scholar 

  16. Wang S, Lin K, Chern J, et al. Severe bacterial infection in transfusion-dependent patients with thalassemia major. Clin Infect Dis 2003;37:984–988

    Article  PubMed  Google Scholar 

  17. Hoe T, Lammi A, Webster B. Homozygous beta-thalassaemia: a review of patients who had splenectomy at the Royal Alexandra Hospital for Children, Sydney. Singapore Med J 1994;35:59–61

    PubMed  CAS  Google Scholar 

  18. Kyriazi Z, Chatzipanagiotou S, Trikka-graphakos E, et al. Serotype, biotype and genomic DNA XbaI restriction fragment analysis of Yersinia enterocolitica, isolated from infected beta-thalassemic and nonthalassemic children in Greece. Clin Microbiol Infect 2000;6:157–158

    Article  PubMed  CAS  Google Scholar 

  19. Angelucci E, Brittenham G, McLaren C, et al. Hepatic iron concentration and total body iron stores in thalassemia major. N Engl J Med 2000;343:327–331.

    Article  PubMed  CAS  Google Scholar 

  20. Kaban G, Czerniach D, Cohen R, et al. Hand-assisted laparoscopic splenectomy in the setting of splenomegaly. Surg Endosc 2004;18:1340–1343

    Article  PubMed  CAS  Google Scholar 

  21. Dimopoulou I, Kremastinos D, Maris T, et al. Respiratory function in patients with thalassaemia and iron overload. Eur Respir J 1999;13:602–605

    Article  PubMed  CAS  Google Scholar 

  22. Cappellini M, Robbiolo L, Bottasso B, et al. Venous thromboembolism and hypercoagulability in splenectomized patients with thalassaemia intermedia. Br J Haematol 2000;111:467–473

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Nicholas Alexakis MD.

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Leandros, E., Alexakis, N., Albanopoulos, K. et al. Hand-assisted Laparoscopic Surgery with a Pfannenstiel Incision in β-Thalassemia Patients: Initial Experience. World J. Surg. 30, 1216–1220 (2006). https://doi.org/10.1007/s00268-005-0542-7

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  • DOI: https://doi.org/10.1007/s00268-005-0542-7

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