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Transabdominal Gastro-esophageal Devascularization and Esophageal Transection for Bleeding Esophageal Varices after Failed Injection Sclerotherapy: Long-Term Follow-Up Report

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Abstract

Background

Management of continued bleeding from esophageal varices despite adequate injection sclerotherapy remains one of the medical and surgical dilemmas. Transabdominal gastroesophageal devascularization and esophageal transection (TGDET) is considered an effective and safe procedure for such patients.

Aim

This study aimed at presenting continued evaluation of TGDET. Various problems influencing the early outcome are discussed, and long-term outcome is analyzed.

Design

This was a prospective clinical descriptive study.

Methods

Prospective data was collected on 142 consecutive patients managed by one group of surgeons over a 5 year-period and 15 years follow-up after failed injection sclerotherapy for variceal bleeding. Evaluation was made in terms of effectiveness in controlling the acute bleeding, postoperative morbidity and mortality, recurrent bleeding, encephalopathy, and long-term survival.

Results

There were 133 men and 9 women. Mean age was 41.8 years. Etiology of portal hypertension was bilharziasis in 54.9% and posthepatitic in 14.8%. Child–Pugh grading on admission was A: 47.2%, B: 28.8%, and C: 14%. Hemorrhage was controlled in all cases. Clinical leak was observed in 5.6%, portal vein thrombosis in 6.3%, and staple line erosion in 2.1% of cases. No patient developed encephalopathy. In-hospital mortality was 12.7%. Complete eradication of varices was observed in 70.6% patients. Recurrent variceal bleeding was noticed in 6.9% of cases. Actuarial 15-year survival for Child–Pugh A patients was 44%, B was 22.5%, and none for C.

Conclusion

TGDET remains a safe and effective procedure after failure of sclerotherapy when other alternatives are either not indicated or not available.

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Acknowledgements

The authors are thankful to the consultant staff of the Departments of Gastroenterology, Histopathology and Radiology of Riyadh Medical Complex for their cooperation in collection of respective data and necessary information.

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Authors and Affiliations

  1. Department of General Surgery, Riyadh Medical Complex, Riyadh, Kingdom of Saudi Arabia

    Shabir Ahmad Qazi, Kamran Khalid, Abdul Majeed Abdul Hameed, Khalid Al-Wahabi, Radwan Galul & Saleh M. Al-Salamah

  2. Kamran Khalid, House No. 321-A, Johar Town, Lahore, 53780, Pakistan

    Kamran Khalid

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  1. Shabir Ahmad Qazi
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  2. Kamran Khalid
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  3. Abdul Majeed Abdul Hameed
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  4. Khalid Al-Wahabi
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  6. Saleh M. Al-Salamah
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Correspondence to Kamran Khalid.

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Qazi, S.A., Khalid, K., Hameed, A.M. et al. Transabdominal Gastro-esophageal Devascularization and Esophageal Transection for Bleeding Esophageal Varices after Failed Injection Sclerotherapy: Long-Term Follow-Up Report. World J. Surg. 30, 1329–1337 (2006). https://doi.org/10.1007/s00268-005-0372-7

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