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Diagnosis and Treatment of Lacrimal Gland Prolapse: A Narrative Review

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  • Eyelid Surgery
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Abstract

Background

Lacrimal gland prolapse (LGP) is considered to be one of the causes for upper eyelid contour abnormality that should be recognized and treated properly to yield satisfactory outcomes in blepharoplasty. To describe current findings about the prevalence, pre- and intraoperative diagnosis of LGP and its treatment options.

Methods

PubMed and Google Scholar were thoroughly searched for articles published describing the diagnosis and treatment of LGP.

Results

The reported prevalence of LGP by various authors varies between 10 and 60% based on their preoperative or intraoperative reports. Techniques such as dacryoadenopexy, modified dacryoadenopexy, and dacryoplasty have been described to secure the prolapsed lacrimal gland back into its original position. Additionally, creating a Whitnall’s barrier has also been suggested as a method to reposition the gland. While all these surgical procedures have shown promising immediate results, there is a lack of published data on their long-term outcomes.

Conclusion

Diagnosis and proper treatment of LGP could enhance the cosmetic results of upper eyelid blepharoplasty.

Level of Evidence IV

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References

  1. Horton CE, Carraway JH, Potenza AD (1978) Treatment of a lacrimal bulge in blepharoplasty by repositioning the gland. Plast Reconstr Surg 61(5):701–702. https://doi.org/10.1097/00006534-197805000-00006

    Article  CAS  PubMed  Google Scholar 

  2. Vatansever M (2023) Modified lacrimal gland suspension technique in patients who underwent upper eyelid blepharoplasty. J Craniofac Surg. https://doi.org/10.1097/scs.0000000000009538

    Article  PubMed  Google Scholar 

  3. Eshraghi B, Ghadimi H (2020) Lacrimal gland prolapse in upper blepharoplasty. Orbit 39(3):165–170. https://doi.org/10.1080/01676830.2019.1649434

    Article  PubMed  Google Scholar 

  4. Kashkouli MB, Tabrizi A, Ghazizadeh M, Khademi B, Karimi N (2019) Supine test: a new test for detecting lacrimal gland prolapse before upper blepharoplasty. Ophthalmic Plast Reconstr Surg 35(6):581–585. https://doi.org/10.1097/iop.0000000000001397

    Article  PubMed  Google Scholar 

  5. Massry GG (2011) Prevalence of lacrimal gland prolapse in the functional blepharoplasty population. Ophthalmic Plast Reconstr Surg 27(6):410–413. https://doi.org/10.1097/IOP.0b013e31821d852e

    Article  PubMed  Google Scholar 

  6. Fakih-Gomez N, Zarate JM, Martins L, Lindo Delgadillo LM (2023) Fakih-gomez I contemporary upper blepharoplasty: volumetric contouring concept. Am J Cosmetic Surg. https://doi.org/10.1177/07488068231171313

    Article  Google Scholar 

  7. Huang S, Juniat V, James C, McNab A, Selva D (2023) Histopathological characteristics of lacrimal gland prolapse. Ophthalmic Plast Reconstr Surg 39(4):389–393. https://doi.org/10.1097/iop.0000000000002335

    Article  PubMed  Google Scholar 

  8. Zhou J, Ding J, Li D (2021) Blepharochalasis: clinical and epidemiological characteristics, surgical strategy and prognosis– a retrospective cohort study with 93 cases. BMC Ophthalmol 21(1):313. https://doi.org/10.1186/s12886-021-02049-4

    Article  PubMed  PubMed Central  Google Scholar 

  9. Alyahya GA, Bangsgaard R, Prause JU, Heegaard S (2005) Occurrence of lacrimal gland tissue outside the lacrimal fossa: comparison of clinical and histopathological findings. Acta Ophthalmol Scand 83(1):100–103. https://doi.org/10.1111/j.1600-0420.2005.00365.x

    Article  PubMed  Google Scholar 

  10. Kashkouli MB, Heirati A, Pakdel F (2011) Lacrimal gland fistula after upper eyelid blepharoplasty. Middle East Afr J Ophthalmol 18(4):326–327. https://doi.org/10.4103/0974-9233.90139

    Article  PubMed  PubMed Central  Google Scholar 

  11. Conrady CD, Joos ZP, Patel BC (2016) Review: the lacrimal gland and its role in dry eye. J Ophthalmol 2016;2016:7542929. https://doi.org/10.1155/2016/7542929

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Petrelli RL (1988) The treatment of lacrimal gland prolapse in blepharoplasty. Ophthalmic Plast Reconstr Surg 4(3):139–142. https://doi.org/10.1097/00002341-198804030-00003

    Article  CAS  PubMed  Google Scholar 

  13. Castañares S (1979) Prolapse of the lacrimal gland: findings and management during blepharoplasty. Aesthetic Plast Surg 3(1):111–118. https://doi.org/10.1007/BF01577843

    Article  PubMed  Google Scholar 

  14. Smith B, Petrelli R (1978) Surgical repair of prolapsed lacrimal glands. Arch Ophthalmol 96(1):113–114. https://doi.org/10.1001/archopht.1978.03910050069017

    Article  CAS  PubMed  Google Scholar 

  15. Çakmak S, Göncü T (2014) Lacrimal gland prolapse in two cases of blepharochalasis syndrome and its treatment. Int Ophthalmol 34(2):293–295. https://doi.org/10.1007/s10792-013-9766-y

    Article  PubMed  Google Scholar 

  16. Hundal KS, Mearza AA, Joshi N (2004) Lacrimal gland prolapse in blepharochalasis. Eye (Lond) 18(4):429–430. https://doi.org/10.1038/sj.eye.6700668

    Article  CAS  PubMed  Google Scholar 

  17. Gagliardo C, Radellini S, Morreale Bubella R, Falanga G, Richiusa P, Vadalà M, Ciresi A, Midiri M, Giordano C (2020) Lacrimal gland herniation in Graves ophthalmopathy: a simple and useful MRI biomarker of disease activity. Eur Radiol 30(4):2138–2141. https://doi.org/10.1007/s00330-019-06570-5

    Article  PubMed  Google Scholar 

  18. Gao Y, Chang Q, Li Y, Zhang H, Hou Z, Zhang Z, Li Z, Li D (2022) Correlation between extent of lacrimal gland prolapse and clinical features of thyroid-associated ophthalmopathy: a retrospective observational study. BMC Ophthalmol 22(1):66. https://doi.org/10.1186/s12886-022-02270-9

    Article  PubMed  PubMed Central  Google Scholar 

  19. Beer GM, Kompatscher P (1994) A new technique for the treatment of lacrimal gland prolapse in blepharoplasty. Aesthetic Plast Surg 18(1):65–69. https://doi.org/10.1007/bf00444250

    Article  CAS  PubMed  Google Scholar 

  20. Smith B, Lisman RD (1983) Dacryoadenopexy as a recognized factor in upper lid blepharoplasty. Plast Reconstr Surg 71(5):629–632. https://doi.org/10.1097/00006534-198305000-00008

    Article  CAS  PubMed  Google Scholar 

  21. Petrelli RL (1986) The prolapsed lacrimal gland in blepharoplasty. Orbit 5(4):267–271. https://doi.org/10.3109/01676838609036059

    Article  Google Scholar 

  22. Choudhary S, Khanna S, Mantri R, Arora P, Jain R, Dutta S (2018) Lacrimoplasty: a new bone fixation technique for recurrent lacrimal gland prolapse. Eur J Plastic Surg. https://doi.org/10.1007/s00238-017-1388-6

    Article  Google Scholar 

  23. Yang C, Guo X, Du L, Song G, Zong X, Zhang D, Du H, Dong X, Zhao J, Jin X (2021) A modified procedure for single-eyelid asian females with lacrimal gland prolapse: lacrimal gland reposition combined with fat transposition in double-eyelid operation. Aesthetic Plast Surg 45(4):1611–1619. https://doi.org/10.1007/s00266-021-02213-7

    Article  PubMed  Google Scholar 

  24. Jafarpour S, Kashkouli MB (2022) Re: a modified procedure for single-eyelid asian females with lacrimal gland prolapse: lacrimal gland reposition combined with fat transposition in double-eyelid operation. Aesthetic Plast Surg 46(1):214–215. https://doi.org/10.1007/s00266-021-02476-0

    Article  PubMed  Google Scholar 

  25. Mathewson PA, Athwal S, Hyer JN, Ezra DG (2023) Whitnall’s barrier: a technique for the management of lacrimal gland prolapse. Plast Reconstr Surg. https://doi.org/10.1097/prs.0000000000010563

    Article  PubMed  Google Scholar 

  26. Guyuron B, DeLuca L (1996) Aesthetic and functional outcomes of dacryoadenopexy. Aesthetic Surg J 16(2):138–141. https://doi.org/10.1016/S1090-820X(96)70037-7

    Article  Google Scholar 

  27. Henares Chavarino ÁA, Estiragués Cerdá M, Ros Magallón A, Vicente Ruiz M, Arroyo Pérez Í, Bazán Álvarez A (2023) Correction of lacrimal gland ptosis in blepharoplasty: a systematic review. Ophthalmic Plast Reconstr Surg 39(5):427–432. https://doi.org/10.1097/iop.0000000000002388

    Article  PubMed  Google Scholar 

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Correspondence to Ali Aghajani.

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Eshraghi, B., Najafi, M., Babaei, L. et al. Diagnosis and Treatment of Lacrimal Gland Prolapse: A Narrative Review. Aesth Plast Surg (2024). https://doi.org/10.1007/s00266-024-04017-x

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