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Systemic Tranexamic Acid for Reduced Postoperative Blood Loss and Less Bleeding Complications in Fleur-de-lis Abdominoplasty and Apronectomy

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  • Body Contouring
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Abstract

Background

Strategies minimizing surgical bleeding, including the antifibrinolytic agent tranexamic acid, play a crucial role in clinical practice to optimize overall surgical outcomes. Despite its proven efficacy in various clinical fields, there is a limited understanding regarding the use of tranexamic acid in plastic and aesthetic procedures. This study is the first investigating the effects of systemically administered tranexamic acid on postoperative blood loss and bleeding complications in fleur-de-lis abdominoplasties and apronectomies.

Methods

Patients who received 1 g tranexamic acid (n = 44) during fleur-de-lis abdominoplasty or apronectomy were retrospectively compared with those who did not (n = 44). In this context, the outcome parameters 24-h and total drain fluid production, drain time, hospital stay, absolute and relative drop in hemoglobin and hematocrit level as well as bleeding complications such as blood transfusion, hematoma puncture and evacuation were evaluated.

Results

Tranexamic acid significantly decreased both drainage volume in 24 h (40.5%, p = 0.0046) and total drain fluid production (42.5%, p = 0.0017). Moreover, a shorter drainage time (19.4%, p = 0.0028) and hospital stay (21.4%, p = 0.0009) were observed. The administration of tranexamic acid was also associated with a reduced postoperative decline in hemoglobin and hematocrit levels. Notably, no bleeding complications were observed in patients who received tranexamic acid, while 6 events occurred in patients without (p = 0.0262).

Conclusion

Systemic administration of tranexamic acid effectively reduced postoperative blood loss and bleeding complications in fleur-de-lis abdominoplasties and apronectomies.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

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Funding

This study did not receive external funding.

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Authors and Affiliations

  1. Department of Plastic and Aesthetic Surgery, Reconstructive and Hand Surgery, Agaplesion Markus Hospital, Wilhelm-Epstein-Straße 4, 60431, Frankfurt am Main, Germany

    Carolin Wachtel, Jens Rothenberger, Ines Ana Ederer & Ulrich Rieger

  2. Department of Plastic, Reconstructive and Aesthetic Surgery, Diakonie Hospital, Bad Kreuznach, Germany

    Jens Rothenberger

  3. Department of Anesthesiology und Pain Medicine, Agaplesion Markus Hospital, Frankfurt am Main, Germany

    Jochen Souquet

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  1. Carolin Wachtel
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  2. Jens Rothenberger
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  3. Ines Ana Ederer
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  4. Jochen Souquet
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  5. Ulrich Rieger
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Correspondence to Carolin Wachtel.

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Wachtel, C., Rothenberger, J., Ederer, I.A. et al. Systemic Tranexamic Acid for Reduced Postoperative Blood Loss and Less Bleeding Complications in Fleur-de-lis Abdominoplasty and Apronectomy. Aesth Plast Surg (2024). https://doi.org/10.1007/s00266-024-03992-5

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