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Three-Dimensional Photography for Evaluating the Effectiveness of Botulinum Toxin Injection for Masseter Hypertrophy

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  • Facial Surgery
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Abstract

Background

Masseter hypertrophy is a common condition that causes a undesirable square face, and often treated with botulinum toxin type A (BoNTA). Subjective assessments of BoNTA effectiveness vary from physician to patient, necessitating an objective approach for evaluation. This study introduces three-dimensional photography (3DP) for the first time in clinical assessment to evaluate BoNTA treatment for masseter hypertrophy.

Methods

Ten patients received 36U of BoNTA at three injection points on each side masseter muscle. 3DP scanner using Artec Eva® was taken at the first, third, and sixth postoperative months for objective evaluation. Patient’s self-perceived prominence, patients self-rated satisfaction, and physicians provided 5-grade scores were the subjective indicators.

Results

A significant decrease in left masseter volume at the sixth month (P = 0.002, P = 0.004 at rest and clenching, respectively) was observed. Patient’s self-perceived prominence decreased at the first (P = 0.021) and third (P = 0.039) months. Physicians’ scores significantly decreased at all postoperative months. No significant changes were noted in the right masseter volume and patients self-rated satisfaction. Patient self-rated satisfaction did not consistently correlate with objective measures, except for left masseter with clenching at the sixth month.

Conclusion

Three-dimensional photography accurately quantifies facial changes post-BoNTA treatment. Despite objective improvements, patient satisfaction may not align consistently. Reliable assessment tools are crucial in cosmetic surgery to manage expectations and prevent disputes.

Level of Evidence IV

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Acknowledgments

This study was supported by grants TSGH-D-110161 from Tri-Service General Hospital. We would like to acknowledge the contributions of Medical 3D Printing Center, Tri-Service General Hospital, National Defense Medical Center for processing 3DP, and Chung-Yu Lai and Ya-Hsin Chen for their assistance with data collection and statistics.

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Correspondence to Shyi-Gen Chen.

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The study was approved by the Institutional Review Board of the Medical Ethics Committee of the Tri-Service General Hospital (application no. B202005119). All procedures involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. All identifying data were deleted before data analysis. Patients’ photographs are published with their consent.

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Huang, DW., Lai, CY., Chen, JE. et al. Three-Dimensional Photography for Evaluating the Effectiveness of Botulinum Toxin Injection for Masseter Hypertrophy. Aesth Plast Surg (2024). https://doi.org/10.1007/s00266-024-03974-7

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