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Trigeminal Neuralgia after Hyaluronic Acid and Botox Injection

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  • Non-Surgical Aesthetic
  • Published:
Aesthetic Plastic Surgery Aims and scope Submit manuscript

Abstract

A rare case of trigeminal neuralgia following injections of Hyaluronic Acid and Botox was documented. In addressing the severe pain and swelling caused by the injection, a novel combination therapy was employed, notably including 5-fluorouracil. The significant improvement observed in this case not only provided clinical insights but also spurred further investigation into the underlying mechanisms linking trigeminal nerve damage to local dermal filler injections. The aim was to glean new medical perspectives and develop practical preventive strategies to mitigate such complications in future cases. This approach highlights the importance of understanding and addressing the potential neurological impacts of cosmetic procedures.

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Data Availability

All relevant data are within the paper and its Supporting Information files.

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Funding

The authors have no financial interests to declare in relation to the content of this article.

Author information

Author notes

  1. Qingqian Wei and Liya Jiang have contributed equally to this work.

Authors and Affiliations

  1. Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shijingshan District, Thirty-three Badachu Road, Beijing, People’s Republic of China

    Qingqian Wei

  2. Department of Cicatrix Minimally Invasive Treatment Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100144, People’s Republic of China

    Liya Jiang

  3. Department of Cicatrix Minimally Invasive Treatment Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100144, People’s Republic of China

    Yingzi Li

  4. Department of Cicatrix Minimally Invasive Treatment Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100144, People’s Republic of China

    Ziming Zhang

  5. Department of Cicatrix Minimally Invasive Treatment Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100144, People’s Republic of China

    Xueshang Su

  6. Department of Cicatrix Minimally Invasive Treatment Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Thirty-three Badachu Road, Shijingshan District, Beijing, 100144, People’s Republic of China

    Jun Zhuang & Jintian Hu

Authors
  1. Qingqian Wei
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Contributions

Q.W. and L.J. participated in the clinical application of the technique and provided the methodology for the study, Y.L. analyzed the data and drafted the article. The remaining authors have contributed to refining the ideas, discussing the results and revising the manuscript. All the authors approved the submitted version.

Corresponding author

Correspondence to Jintian Hu.

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Conflict of Interest

The authors declare that they have no conflicts of interest to disclose.

Ethical Approval

The study was approved by the Ethics Committee of Peking Union Medical College.

Human and Animal Rights

This article does not contain any studies with human participants or animals performed by any of the authors.

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For this type of study informed consent is not required.

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Wei, Q., Jiang, L., Li, Y. et al. Trigeminal Neuralgia after Hyaluronic Acid and Botox Injection. Aesth Plast Surg (2024). https://doi.org/10.1007/s00266-024-03915-4

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  • DOI: https://doi.org/10.1007/s00266-024-03915-4

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