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Dorsal Hand Rejuvenation: A Systematic Review of the Literature

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  • Fat Injection
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Abstract

Background

Dorsal hand appearance undergoes changes with aging. Grading systems have been designed to provide numerical scores to dorsal hand appearance. Various modalities have been utilized to improve the aesthetic appearance and rejuvenate the dorsal hand.

Methods

The MEDLINE database was searched for articles investigating dorsal hand rejuvenation. Studies were grouped by method including fat grafting, injectable filler, laser/light-based treatments and miscellaneous treatments. Treatment protocols and outcomes were compiled along with patient information and complications.

Results

Forty-six articles were identified for inclusion. This included 9 studies of fat grafting procedures, 20 studies of injectable filler, 10 studies of laser/light-based treatments and 7 miscellaneous. Most studies showed overall good results with high patient satisfaction. Satisfaction rates were lower in laser/light-based treatments compared with the other modalities. The average patient age for included studies ranged from 41.5 to 69. Across all studies, 96.8% of patients were female and 3.2% male.

Conclusions

Procedures for dorsal hand rejuvenation in the literature include procedures to address volume atrophy and superficial wrinkling. These procedures are overall safe with most studies reporting no complications or only mild adverse events. With high satisfaction rates and anecdotal reports of increasing patient interest, these procedures represent a developing area in aesthetic surgery likely to continue increasing in popularity.

Level of Evidence III

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References

  1. Bains RD, Thorpe H, Southern S (2006) Hand aging: patients’ opinions. Plast Reconstr Surg 117(7):2212–2218. https://doi.org/10.1097/01.prs.0000218712.66333.97

    Article  CAS  PubMed  Google Scholar 

  2. Goldman A, Prati C, Rossato F (2008) Hand rejuvenation using intense pulsed light. J Cutan Med Surg 12(3):107–113. https://doi.org/10.2310/7750.2008.07025

    Article  PubMed  Google Scholar 

  3. Jakubietz RG, Jakubietz MG, Koss D, Gruenert JG (2005) Defining the basic aesthetics of the hand. Aesthet Plast Surg 29(6):546–551. https://doi.org/10.1007/s00266-005-0100-6

    Article  Google Scholar 

  4. Butterwick KJ (2002) Lipoaugmentation for aging hands: a comparison of the longevity and aesthetic results of centrifuged versus noncentrifuged fat. Dermatol Surg 28(11):987–991. https://doi.org/10.1046/j.1524-4725.2002.02096.x

    Article  PubMed  Google Scholar 

  5. Redaelli A (2006) Cosmetic use of polylactic acid for hand rejuvenation: report on 27 patients. J Cosmet Dermatol 5(3):233–238. https://doi.org/10.1111/j.1473-2165.2006.00259.x

    Article  CAS  PubMed  Google Scholar 

  6. Moradi A, Allen S, Bank D et al (2019) A prospective, multicenter, randomized, evaluator-blinded, split-hand study to evaluate the effectiveness and safety of large-gel-particle hyaluronic acid with lidocaine for the correction of volume deficits in the dorsal hand. Plast Reconstr Surg 144(4):586e-e596. https://doi.org/10.1097/prs.0000000000006070

    Article  CAS  PubMed  Google Scholar 

  7. Carruthers A, Carruthers J, Hardas B et al (2008) A validated hand grading scale. Dermatol Surg 34(Suppl 2):S179–S183. https://doi.org/10.1111/j.1524-4725.2008.34368

    Article  CAS  PubMed  Google Scholar 

  8. Lee JH, Choi YS, Park ES et al (2019) A novel photonumeric hand grading scale for hand rejuvenation. Arch Plast Surg 46(4):359–364. https://doi.org/10.5999/aps.2019.00521

    Article  PubMed  PubMed Central  Google Scholar 

  9. Aboudib Junior JH, de Castro CC, Gradel J (1992) Hand rejuvenescence by fat filling. Ann Plast Surg 28(6):559–564

    Article  CAS  Google Scholar 

  10. Agostini T, Perello R (2015) Lipomodeling: an innovative approach to global volumetric rejuvenation of the hand. Aesthet Surg J 35(6):708–714. https://doi.org/10.1093/asj/sju163

    Article  PubMed  Google Scholar 

  11. Butterwick KJ, Bevin AA, Iyer S (2006) Fat transplantation using fresh versus frozen fat: a side-by-side two-hand comparison pilot study. Dermatol Surg 32(5):640–644. https://doi.org/10.1111/j.1524-4725.2006.32135.x

    Article  CAS  PubMed  Google Scholar 

  12. Fantozzi F (2017) Hand rejuvenation with fat grafting: a 12-year single-surgeon experience. Eur J Plast Surg 40(5):457–464. https://doi.org/10.1007/s00238-017-1337-4

    Article  PubMed  PubMed Central  Google Scholar 

  13. Coleman SR (2002) Hand rejuvenation with structural fat grafting. Plast Reconstr Surg 110(7):1731–1744. https://doi.org/10.1097/01.Prs.0000033936.43357.08

    Article  PubMed  Google Scholar 

  14. Sterodimas A, Boriani F, Nicaretta B, Pereira LH (2018) Hand rejuvenation by stromal enriched lipograft. J Plast Reconstr Aesthet Surg 71(10):1507–1517. https://doi.org/10.1016/j.bjps.2018.07.029

    Article  PubMed  Google Scholar 

  15. Yun-Nan L, Shu-Hung H, Tsung-Ying L et al (2018) Micro-autologous fat transplantation for rejuvenation of the dorsal surface of the aging hand. J Plast Reconstr Aesthet Surg 71(4):573–584. https://doi.org/10.1016/j.bjps.2017.09.012

    Article  PubMed  Google Scholar 

  16. Zhou J, Xie Y, Wang WJ et al (2017) Hand rejuvenation by targeted volume restoration of the dorsal fat compartments. Aesthet Surg J 38(1):92–100. https://doi.org/10.1093/asj/sjx091

    Article  PubMed  Google Scholar 

  17. Brandt FS, Cazzaniga A, Strangman N, Coleman J, Axford-Gatley R (2012) Long-term effectiveness and safety of small gel particle hyaluronic acid for hand rejuvenation. Dermatol Surg 38(7 Pt 2):1128–1135. https://doi.org/10.1111/j.1524-4725.2011.02282.x

    Article  CAS  PubMed  Google Scholar 

  18. Inglefield C (2009) Nonsurgical hand rejuvenation with Dermicol-P35 30G. Aesthet Surg J 29(3 Suppl):S19-21. https://doi.org/10.1016/j.asj.2009.03.008

    Article  PubMed  Google Scholar 

  19. Dallara JM (2012) A prospective, noninterventional study of the treatment of the aging hand with Juvederm Ultra® 3 and Juvederm® Hydrate. Aesthetic Plast Surg 36(4):949–954. https://doi.org/10.1007/s00266-012-9890-5

    Article  PubMed  Google Scholar 

  20. Frank K, Koban K, Targosinski S et al (2018) The anatomy behind adverse events in hand volumizing procedures: retrospective evaluations of 11 years of experience. Plast Reconstr Surg 141(5):650e-e662. https://doi.org/10.1097/prs.0000000000004211

    Article  CAS  PubMed  Google Scholar 

  21. Goldman MP, Moradi A, Gold MH et al (2018) Calcium hydroxylapatite dermal filler for treatment of dorsal hand volume loss: results from a 12-month, multicenter, randomized. Blind Trial Dermatol Surg 44(1):75–83. https://doi.org/10.1097/dss.0000000000001203

    Article  CAS  PubMed  Google Scholar 

  22. Gubanova EI, Starovatova PA, Rodina MY (2015) 12-month effects of stabilized hyaluronic acid gel compared with saline for rejuvenation of aging hands. J Drugs Dermatol 14(3):288–298

    CAS  PubMed  Google Scholar 

  23. Gubanova EI, Starovatova PA (2015) A prospective, comparative, evaluator-blind clinical study investigating efficacy and safety of two injection techniques with Radiesse® for the correction of skin changes in aging hands. J Cutan Aesthet Surg 8(3):147–152. https://doi.org/10.4103/0974-2077.167271

    Article  PubMed  PubMed Central  Google Scholar 

  24. Lacarrubba F, Tedeschi A, Nardone B, Micali G (2008) Mesotherapy for skin rejuvenation: assessment of the subepidermal low-echogenic band by ultrasound evaluation with cross-sectional B-mode scanning. Dermatol Ther 21(Suppl 3):S1-5. https://doi.org/10.1111/j.1529-8019.2008.00234.x

    Article  PubMed  Google Scholar 

  25. Leclere FM, Vogelin E, Mordon S et al (2012) Nonanimal stabilized hyaluronic acid for tissue augmentation of the dorsal hands: a prospective study on 38 patients. Aesthet Plast Surg 36(6):1367–75. https://doi.org/10.1007/s00266-012-9974-2

    Article  Google Scholar 

  26. Levenberg A, Halachmi S, Arad-Cohen A, Ad-El D, Cassuto D, Lapidoth M (2010) Clinical results of skin remodeling using a novel pneumatic technology. Int J Dermatol 49(12):1432–9. https://doi.org/10.1111/j.1365-4632.2010.04627.x

    Article  PubMed  Google Scholar 

  27. Man J, Rao J, Goldman M (2008) A double-blind, comparative study of nonanimal-stabilized hyaluronic acid versus human collagen for tissue augmentation of the dorsal hands. Dermatol Surg 34(8):1026–31. https://doi.org/10.1111/j.1524-4725.2008.34201.x

    Article  CAS  PubMed  Google Scholar 

  28. Marmur ES, Al Quran H, De Sa Earp AP, Yoo JY (2009) A five-patient satisfaction pilot study of calcium hydroxylapatite injection for treatment of aging hands. Dermatol Surg 35(12):1978–84. https://doi.org/10.1111/j.1524-4725.2009.01312.x

    Article  CAS  PubMed  Google Scholar 

  29. Sadick NS, Anderson D, Werschler WP (2008) Addressing volume loss in hand rejuvenation: a report of clinical experience. J Cosmet Laser Ther 10(4):237–41. https://doi.org/10.1080/14764170802524429

    Article  PubMed  Google Scholar 

  30. Sadick NS (2011) A 52-week study of safety and efficacy of calcium hydroxylapatite for rejuvenation of the aging hand. J Drugs Dermatol 10(1):47–51

    PubMed  Google Scholar 

  31. Tedeschi A, Lacarrubba F, Micali G (2015) Mesotherapy with an Intradermal hyaluronic acid formulation for skin rejuvenation: an intrapatient, placebo-controlled, long-term trial using high-frequency ultrasound. Aesthet Plast Surg 39(1):129–33. https://doi.org/10.1007/s00266-014-0432-1

    Article  Google Scholar 

  32. Figueiredo VM (2013) A five-patient prospective pilot study of a polycaprolactone based dermal filler for hand rejuvenation. J Cosmet Dermatol 12(1):73–7. https://doi.org/10.1111/jocd.12020

    Article  PubMed  Google Scholar 

  33. Wilkerson EC, Goldberg DJ (2018) Small-particle hyaluronic acid gel treatment of photoaged hands. Dermatol Surg 44(1):68–74. https://doi.org/10.1097/dss.0000000000001251

    Article  CAS  PubMed  Google Scholar 

  34. Williams S, Tamburic S, Stensvik H, Weber M (2009) Changes in skin physiology and clinical appearance after microdroplet placement of hyaluronic acid in aging hands. J Cosmet Dermatol 8(3):216–25. https://doi.org/10.1111/j.1473-2165.2009.00447.x

    Article  PubMed  Google Scholar 

  35. Horibe EK, Ferreira LM, Horibe EK, Lima AH, Cruz N (2002) Er: YAG laser versus blue peel in the treatment of photoaging hands. J Clin Laser Med Surg 20(4):207–13. https://doi.org/10.1089/104454702760230537

    Article  PubMed  Google Scholar 

  36. Jimenez G, Spencer JM (1999) Erbium: YAG laser resurfacing of the hands, arms, and neck. Dermatol Surg 25(11):831–4. https://doi.org/10.1046/j.1524-4725.1999.99085.x

    Article  CAS  PubMed  Google Scholar 

  37. Robati RM, Asadi E, Shafiee A, Namazi N, Talebi A (2018) Efficacy of long pulse Nd: YAG laser versus fractional Er: YAG laser in the treatment of hand wrinkles. Lasers Med Sci 33(3):461–67. https://doi.org/10.1007/s10103-017-2351-2

    Article  PubMed  Google Scholar 

  38. Sadick N, Schecter AK (2004) Utilization of the 1320-nm Nd: YAG laser for the reduction of photoaging of the hands. Dermatol Surg 30(8):1140–4. https://doi.org/10.1111/j.1524-4725.2004.30341.x

    Article  PubMed  Google Scholar 

  39. Sasaya H, Kawada A, Wada T, Hirao A, Oiso N (2011) Clinical effectiveness of intense pulsed light therapy for solar lentigines of the hands. Dermatol Ther 24(6):584–6. https://doi.org/10.1111/j.1529-8019.2012.01426.x

    Article  PubMed  Google Scholar 

  40. Maruyama S (2016) Hand rejuvenation using standard intense pulsed light (IPL) in Asian patients. Laser Ther 25(1):43–54. https://doi.org/10.5978/islsm.16-OR-04

    Article  PubMed  PubMed Central  Google Scholar 

  41. Stebbins WG, Hanke CW (2011) Ablative fractional CO2 resurfacing for photoaging of the hands: pilot study of 10 patients. Dermatol Ther 24(1):62–70. https://doi.org/10.1111/j.1529-8019.2010.01379.x

    Article  PubMed  Google Scholar 

  42. Verner I, Kutscher TD (2017) Clinical evaluation of the efficacy and safety of combined bipolar radiofrequency and optical energies vs. optical energy alone for the treatment of aging hands. Lasers Med Sci 32(6):1387–1392. https://doi.org/10.1007/s10103-017-2257-z

    Article  PubMed  Google Scholar 

  43. Oktem A, Kocyigit P (2016) Comparison of effectiveness of 1,064-nm Nd: YAG laser and Nd: YAG laser-IPL combination treatments in hand skin rejuvenation. J Cosmet Laser Ther 18(5):270–4. https://doi.org/10.3109/14764172.2016.1157366

    Article  PubMed  Google Scholar 

  44. Alster TS, Konda S (2007) Plasma skin resurfacing for regeneration of neck, chest, and hands: investigation of a novel device. Dermatol Surg 33(11):1315–21. https://doi.org/10.1111/j.1524-4725.2007.33282.x

    Article  CAS  PubMed  Google Scholar 

  45. Duffy DM, Garcia C, Clark RE (1999) The role of sclerotherapy in abnormal varicose hand veins. Plast Reconstr Surg 104(5):1474–9

    Article  CAS  Google Scholar 

  46. Gold MH, Gallagher C (2013) An evaluation of the benefits of a topical treatment in the improvement of photodamaged hands with age spots, freckles, and/or discolorations. J Drugs Dermatol 12(12):1468–1472

    PubMed  Google Scholar 

  47. Handle M, Bonfatti-Ribeiro LM, Barcaro-Machado BH, Pitanguy I (2011) Minimal-scar handlift: a new surgical approach. Aesthet Surg J 31(8):953–62. https://doi.org/10.1177/1090820x11424279

    Article  PubMed  Google Scholar 

  48. Roberts WE, Colvan L, Gotz V (2017) Topical treatment of aging hands: brief report. J Clin Aesthet Dermatol 10(8):37–41

    PubMed  PubMed Central  Google Scholar 

  49. Schlessinger J, Saxena S, Mohr S (2016) Assessment of a novel anti-aging hand cream. J Drugs Dermatol 15(4):496–503

    CAS  PubMed  Google Scholar 

  50. Shamma AR, Guy RJ (2007) Laser ablation of unwanted hand veins. Plast Reconstr Surg 120(7):2017–24. https://doi.org/10.1097/01.prs.0000287331.23007.01

    Article  CAS  PubMed  Google Scholar 

  51. Galderma FDA (2018) Approval of Restylane Lyft for Hands. Secondary FDA Approval of Restylane Lyft for Hands. https://www.galderma.com/news/fda-approval-restylaner-lyft-hands.

  52. Niamtu J (2018) Injectable Fillers. In: Niamtu J (ed) Cosmetic Facial Surgery, 2nd edn. Elsevier, Missouri, p 571

    Google Scholar 

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  1. Division of Plastic, Aesthetic and Reconstructive Surgery, DeWitt-Daughtry Family Department of Surgery, University Of Miami, Leonard Miller School of Medicine, Clinical Research Building (CRB), 1120 NW 14th Street, 4th floor, Miami, FL, 33136, USA

    Steven Andrew Ovadia, Iakov Vladislavovich Efimenko & Anne Sophie Lessard

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  1. Steven Andrew Ovadia
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Ovadia, S.A., Efimenko, I.V. & Lessard, A.S. Dorsal Hand Rejuvenation: A Systematic Review of the Literature. Aesth Plast Surg 45, 1804–1825 (2021). https://doi.org/10.1007/s00266-020-02077-3

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