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Concentrated Growth Factors Extracted from Blood Plasma Used to Repair Nasal Septal Mucosal Defect After Rhinoplasty

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  • Rhinoplasty
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Abstract

Background

To assess preliminarily the effect of concentrated growth factor (CGF) for repair of nasal septal mucosal defect after rhinoplasty.

Methods

Ten women with mucosal defects of the nasal septum were enrolled from May 2017 to May 2018. Liquid and gel CGF was prepared from each patient’s blood sample using a Medifuge system, including benchtop centrifuge. After debridement of the defect, the prepared liquid CGF was injected around the wound, and a membranous CGF film was applied to the surface. Vaseline gauze was used to pack the nostrils. All patients were treated with CGF at intervals from 3 to 5 days.

Results

After 3 to 12 treatments, all the patients achieved successful repair of the nasal septal mucosal defect, with good appearance and function. During a follow-up of 3 to 6 months, no recurrence was observed.

Conclusion

CGF appeared to have great curative effect for patients with nasal septal mucosal defects after rhinoplasty. The procedure was easy to perform and should be considered worthwhile in clinical practice.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

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Author information

Author notes

  1. Qi-Ming Zhao and Jie Gao have contributed equally to this work.

Authors and Affiliations

  1. Department of Plastic Surgery, Zhejiang Hospital, No. 12 Lingyin Road, Xihu District, Hangzhou, 310013, Zhejiang, China

    Qi-Ming Zhao, Jie Gao, Xiao-xiang Huang, Xiao-ping Chen & Xin Wang

Authors
  1. Qi-Ming Zhao
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  2. Jie Gao
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  3. Xiao-xiang Huang
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  4. Xiao-ping Chen
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  5. Xin Wang
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Corresponding author

Correspondence to Qi-Ming Zhao.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

This study was approved by the ethics committee of Zhejiang Hospital. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Patients provided written consent for the use of their images.

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Zhao, QM., Gao, J., Huang, Xx. et al. Concentrated Growth Factors Extracted from Blood Plasma Used to Repair Nasal Septal Mucosal Defect After Rhinoplasty. Aesth Plast Surg 44, 511–516 (2020). https://doi.org/10.1007/s00266-019-01474-7

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  • DOI: https://doi.org/10.1007/s00266-019-01474-7

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