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Use of Autologous Fibrin Glue (Platelet-Poor Plasma) in Abdominal Dermolipectomies

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  • Aesthetic
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Abstract

Background

Autologous plasma is endowed with properties that speed up healing, hemostasis, and adhesiveness, in addition to growth factors. Through an established protocol, it was possible to isolate thrombin, as well as the platelet-rich plasma (PRP) and platelet-poor plasma (PPP) fractions. The purpose of this study was to analyze autologous use of thrombin and PPP to foster adhesion between an abdominal dermoadipose flap and the aponeurotic surface in abdominal dermolipectomies.

Methods

The data from 40 patients who underwent abdominal dermolipectomies were analyzed, with 20 patients using thrombin and autologous PPP (Plasma group) and 20 patients with no intervention (Control group). An attempt was made to assess adhesive power by quantifying the serohematic liquid volume gauged during the postoperative days (POD), and also noting the incidence of seroma. Other variables such as age and body mass index (BMI) were also analyzed.

Results

The reduction in the aspiration drain debit was statistically relevant only on the first POD in the Plasma group. There was no reduction in the incidence of seroma in these patients. Similarly, age and BMI did not influence these outcomes.

Conclusion

The PPP fostered adhesion between the abdominal dermoadipose flap and the aponeurotic surface only on the first POD and had no influence whatsoever on the incidence of seroma. There are few reports on the use of PPP for plastic surgery, particularly the autologous type, opening up possibilities for further research projects to expand its use.

Level of Evidence III

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Conflict of interest

The authors have no conflict of interest to disclose

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Authors and Affiliations

  1. Federal University of Rio de Janeiro, Rua Professor Gabizo, 101 apto. 202-Tijuca, Rio de Janeiro, CEP: 20271-063, Brazil

    Angélica Maria Schettino, Diogo Franco, Talita Franco & João Medeiros Tavares Filho

  2. Marcilio Dias Navy Hospital,  Rio de Janeiro, Brazil

    Angélica Maria Schettino

  3. Federal University of Pará, Belém, Pará, Brazil

    Fabiel Spani Vendramin

Authors
  1. Angélica Maria Schettino
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  2. Diogo Franco
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  3. Talita Franco
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  4. João Medeiros Tavares Filho
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  5. Fabiel Spani Vendramin
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Correspondence to Angélica Maria Schettino.

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Schettino, A.M., Franco, D., Franco, T. et al. Use of Autologous Fibrin Glue (Platelet-Poor Plasma) in Abdominal Dermolipectomies. Aesth Plast Surg 36, 1296–1301 (2012). https://doi.org/10.1007/s00266-012-9978-y

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  • DOI: https://doi.org/10.1007/s00266-012-9978-y

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