Abstract
Tumoral calcinosis, a rare benign clinical condition resembling a neoplasm, is characterized by calcium deposits, usually located in the soft tissues around the large joints. It can be primary or secondary to renal failure and hyperparathyroidism. This report describes an unusual case of recurrent tumoral calcinosis presenting as a huge mass infiltrating the skin and muscles of the lumbosacral area. The patient underwent wide excision and reconstruction with bilateral V–Y advancement gluteal fasciocutaneous flaps and at this writing remains disease free 4 years postoperatively. A concise review of the pertinent literature focusing on the diagnosis, treatment options, and preventive measures also is reported.
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References
Mockel G, Buttgereit F, Labs K, Perka C (2005) Tumoral calcinosis revisited: pathophysiology and treatment. Rheumatol Int 25:55–59
Smack D, Norton SA, Fitzpatrick JE (1996) Proposal for a pathogenesis-based classification of tumoral calcinosis. Int J Dermatol 35:265–271
Ichikawa S, Lyles KW, Econs MJ (2005) A novel GALNT3 mutation in a pseudoautosomal dominant form of tumoral calcinosis: evidence that the disorder is autosomal recessive. J Clin Endocrinol Metab 90:2420–2423
Polykandriotis EP, Beutel FK, Horch RE, Grunert J (2004) A case of familial tumoral calcinosis in a neonate and review of the literature. Arch Orthop Trauma Surg 124:563–567
Bittmann S, Gunther MW, Ulus H (2003) Tumoral calcinosis of the gluteal region in a child: case report with overview of different soft tissue calcifications. J Pediatr Surg 38:E4–E7
Olsen KM, Chew FS (2006) Tumoral calcinosis: pearls, polemics, and alternative possibilities. Radiographics 26:871–885
Pola E, Pola R, Gaetani E, De Santis E (2002) Tumoral calcinosis. Lancet 359:1818
Harwood CA, Cook MG, Mortimer PS (1996) Tumoral calcinosis: an unusual cause of cutaneous calcification. Clin Exp Dermatol 21:163–166
McGregor DH, Mowry M, Cherian R, McAnaw M, Poole E (1995) Nonfamilial tumoral calcinosis associated with chronic renal failure and secondary hyperparathyroidism: report of two cases with clinicopathological, immunohistochemical, and electron microscopic findings. Hum Pathol 26:607–613
Rambani R, Dhillon MS, Aggarwal R (2003) Tumoral calcinosis with unusual presentation: a case report. Acta Orthop Belg 69:368–372
Aydin A, Tuncer S, Erer M, Bilgic B (2004) Tumoral calcinosis infiltrating the biceps brachii tendon: excision and reconstruction with allograft: a case report. J Hand Surg Br 29:170–172
Lykoudis EG, Spyropoulou GA (2007) The use of suture anchors in reconstruction of sacral pressure ulcers with gluteal fasciocutaneous advancement flaps. Ann Plast Surg 59:92–94
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Lykoudis, E.G., Seretis, K. & Ristanis, S. Huge Recurrent Tumoral Calcinosis Needing Extensive Excision and Reconstruction: Report of a Rare Case and Brief Literature Review. Aesth Plast Surg 36, 1194–1197 (2012). https://doi.org/10.1007/s00266-012-9923-0
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DOI: https://doi.org/10.1007/s00266-012-9923-0