Control of Postoperative Pain with a Wearable Continuously Operating Pulsed Radiofrequency Energy Device: A Preliminary Study



Pulsed radiofrequency energy (PRFE) has long been reported to have a therapeutic effect on postoperative pain. In this study, a portable, wearable, low-energy-emitting PRFE therapy device was used to determine the control of postoperative pain after breast augmentation surgery.


The study enrolled 18 healthy women who underwent breast augmentation purely for aesthetic considerations. Postoperative pain after surgery was assessed with a 0- to 10-point visual analog scale (VAS). Baseline pain scores were taken at completion of the operation, and the patients were randomly assigned coded PRFE devices that were either active or placebo devices. For 7 days, VAS scores were recorded twice daily (a.m. and p.m.). Medication use also was logged for 7 days. The PRFE devices were left in place and in continuous operation for the 7 days of the study.


All the patients tolerated the PRFE therapy well, and no side effects were reported. The VAS scores for the active group were significantly lower on postoperative day 1. By day 7, the baseline VAS remaining in the active group was 7.9% versus 38% in the placebo group. Together with lower VAS scores, narcotic pain medication use was lower in the patient group that received PRFE therapy.


Postoperative pain is significantly lower with PRFE therapy. According to the findings, PRFE therapy in this form is an excellent, safe, drug-free method of postoperative pain control.

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  1. 1.

    White PF (2008) Pain management after ambulatory surgery: where is the disconnect? Can J Anaesth 55:201–207

    PubMed  Article  Google Scholar 

  2. 2.

    Apfelbaum JL, Chen C, Mehta SS, Gan TJ (2003) Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged (table of contents). Anesth Analg 97:534–540

    PubMed  Article  Google Scholar 

  3. 3.

    Buvanendran A, Kroin JS, Della Valle CJ, Kari M, Moric M, Tuman KJ (2010) Perioperative oral pregabalin reduces chronic pain after total knee arthroplasty: a prospective, randomized, controlled trial. Anesth Analg 110:199–207

    PubMed  Article  CAS  Google Scholar 

  4. 4.

    Andersen KG, Kehlet H (2011) Persistent pain after breast cancer treatment: a critical review of risk factors and strategies for prevention. J Pain 12:725–746

    PubMed  Article  Google Scholar 

  5. 5.

    White PF, Eng M (2007) Fast-track anesthetic techniques for ambulatory surgery. Curr Opin Anaesthesiol 20:545–557

    PubMed  Article  Google Scholar 

  6. 6.

    White PF, Kehlet H, Neal JM, Schricker T, Carr DB, Carli F (2007) The role of the anesthesiologist in fast-track surgery: From multimodal analgesia to perioperative medical care (table of contents). Anesth Analg 104:1380–1396

    PubMed  Article  Google Scholar 

  7. 7.

    Foley-Nolan D, Barry C, Coughlan RJ, O’Connor P, Roden D (1990) Pulsed high-frequency (27 MHz) electromagnetic therapy for persistent neck pain: a double-blind, placebo-controlled study of 20 patients. Orthopedics 13:445–451

    PubMed  CAS  Google Scholar 

  8. 8.

    Aaron RK, Ciombor DM, Simon BJ (2004) Treatment of nonunions with electric and electromagnetic fields. Clin Orthop Relat Res 419:21–29

    PubMed  Article  Google Scholar 

  9. 9.

    Aronofsky DH (1971) Reduction of dental postsurgical symptoms using nonthermal pulsed high-peak-power electromagnetic energy. Oral Surg Oral Med Oral Pathol 32:688–696

    PubMed  Article  CAS  Google Scholar 

  10. 10.

    Nicolle FV, Bentall RM (1982) Use of radiofrequency pulsed energy in the control of postoperative reaction in blepharoplasty. Aesthet Plast Surg 6:169–171

    Article  CAS  Google Scholar 

  11. 11.

    Benazzo F, Zanon G, Pederzini L, Modonesi F, Cardile C, Falez F, Ciolli L, La Cava F, Giannini S, Buda R et al (2008) Effects of biophysical stimulation in patients undergoing arthroscopic reconstruction of anterior cruciate ligament: prospective, randomized, and double-blind study. Knee Surg Sports Traumatol Arthrosc 16:595–601

    PubMed  Article  Google Scholar 

  12. 12.

    Till M, Gubisch W, Frickert G, Reichert H, Schmidt KH (1993) Postoperative management with pulsed high-frequency electromagnetic energy: a clinical study of 38 patients with rhinoseptoplasty. Handchir Mikrochir Plast Chir 25:26–32

    PubMed  CAS  Google Scholar 

  13. 13.

    Frank R (1985) Treatment of the perineum by pulsed electromagnetic therapy. Midwives Chron 98:297–298

    PubMed  CAS  Google Scholar 

  14. 14.

    Silver H (1982) Reduction of capsular contracture with two-stage augmentation mammaplasty and pulsed electromagnetic energy (Diapulse therapy). Plast Reconstr Surg 69:802–808

    PubMed  Article  CAS  Google Scholar 

  15. 15.

    Foley-Nolan D, Moore K, Codd M, Barry C, O’Connor P, Coughlan RJ (1992) Low-energy high-frequency pulsed electromagnetic therapy for acute whiplash injuries: a double-blind randomized controlled study. Scand J Rehabil Med 24:51–59

    PubMed  CAS  Google Scholar 

  16. 16.

    Pennington GM, Danley DL, Sumko MH, Bucknell A, Nelson JH (1993) Pulsed, nonthermal, high-frequency electromagnetic energy (Diapulse) in the treatment of grade I and grade II ankle sprains. Mil Med 158:101–104

    PubMed  CAS  Google Scholar 

  17. 17.

    Wilson DH (1974) Comparison of short-wave diathermy and pulsed electromagnetic energy in treatment of soft tissue injuries. Physiotherapy 60:309–310

    PubMed  CAS  Google Scholar 

  18. 18.

    Cameron BM (1964) A three-phase evaluation of pulsed, high-frequency, radio short waves (Diapulse): 646 patients. Am J Orthop 6:72–78

    PubMed  CAS  Google Scholar 

  19. 19.

    Itoh M, Montemayor JS Jr, Matsumoto E, Eason A, Lee MH, Folk FS (1991) Accelerated wound healing of pressure ulcers by pulsed high-peak power electromagnetic energy (Diapulse). Decubitus 4(24–25):29–34

    Google Scholar 

  20. 20.

    Salzberg CA, Cooper-Vastola SA, Perez F, Viehbeck MG, Byrne DW (1995) The effects of nonthermal pulsed electromagnetic energy on wound healing of pressure ulcers in spinal cord-injured patients: a randomized, double-blind study. Ostomy Wound Manage 41:42–44, 46, 48 passim

    Google Scholar 

  21. 21.

    Stiller MJ, Pak GH, Shupack JL, Thaler S, Kenny C, Jondreau L (1992) A portable pulsed electromagnetic field (PEMF) device to enhance healing of recalcitrant venous ulcers: a double-blind, placebo-controlled clinical trial. Br J Dermatol 127:147–154

    PubMed  Article  CAS  Google Scholar 

  22. 22.

    Fletcher S (2011) Successful treatment of venous stasis ulcers with combination compression therapy and pulsed radiofrequency energy in a patient scheduled for amputation. J Wound Ostomy Cont Nurs 38:91–94

    Article  Google Scholar 

  23. 23.

    Frykberg R, Martin E, Tallis A, Tierney E (2011) A case history of multimodal therapy in healing a complicated diabetic foot wound: negative pressure, dermal replacement, and pulsed radiofrequency energy therapies. Int Wound J 8:132–139

    PubMed  Article  Google Scholar 

  24. 24.

    Frykberg RG, Driver VR, Lavery LA, Armstrong DG, Isenberg RA (2011) The use of pulsed radiofrequency energy therapy in treating lower extremity wounds: results of a retrospective study of a wound registry. Ostomy Wound Manage 57:22–29

    PubMed  Google Scholar 

  25. 25.

    Rawe IM, Vlahovic TC (2011) The use of a portable, wearable form of pulsed radiofrequency electromagnetic energy device for the healing of recalcitrant ulcers: a case report. Int Wound J. doi:10.1111/j.1742-481X.2011.00853.x

  26. 26.

    Heden P, Pilla AA (2008) Effects of pulsed electromagnetic fields on postoperative pain: a double-blind randomized pilot study in breast augmentation patients. Aesthet Plast Surg 32:660–666

    Article  Google Scholar 

  27. 27.

    Rohde C, Chiang A, Adipoju O, Casper D, Pilla AA (2010) Effects of pulsed electromagnetic fields on IL-1 beta and postoperative pain: a double-blind, placebo-controlled pilot study in breast reduction patients. Plast Reconstr Surg 125:1620–1629

    PubMed  Article  CAS  Google Scholar 

  28. 28.

    Strauch B, Herman C, Dabb R, Ignarro LJ, Pilla AA (2009) Evidence-based use of pulsed electromagnetic field therapy in clinical plastic surgery. Aesthet Surg J 29:135–143

    PubMed  Article  Google Scholar 

  29. 29.

    Li Q, Kao H, Matros E, Peng C, Murphy GF, Guo L (2011) Pulsed radiofrequency energy (PRFE) accelerates wound healing in diabetic mice. Plast Reconstr Surg 127:2255–2262

    PubMed  Article  CAS  Google Scholar 

  30. 30.

    Moffett J, Griffin N, Ritz M, George F (2010) Pulsed radiofrequency energy field treatment of cells in culture results in increased expression of genes involved in the inflammation phase of lower extremity diabetic wound healing. J Diabet Foot Complicat 2:57–64

    Google Scholar 

  31. 31.

    Williamson A, Hoggart B (2005) Pain: a review of three commonly used pain rating scales. J Clin Nurs 14:798–804

    PubMed  Article  Google Scholar 

  32. 32.

    White PF, Kehlet H (2010) Improving postoperative pain management: what are the unresolved issues? Anesthesiology 112:220–225

    PubMed  Article  Google Scholar 

  33. 33.

    Gilron I, Orr E, Tu D, Mercer CD, Bond D (2009) A randomized, double-blind, controlled trial of perioperative administration of gabapentin, meloxicam, and their combination for spontaneous and movement-evoked pain after ambulatory laparoscopic cholecystectomy. Anesth Analg 108:623–630

    PubMed  Article  CAS  Google Scholar 

  34. 34.

    White PF, Sacan O, Tufanogullari B, Eng M, Nuangchamnong N, Ogunnaike B (2007) Effect of short-term postoperative celecoxib administration on patient outcome after outpatient laparoscopic surgery. Can J Anaesth 54:342–348

    PubMed  Article  Google Scholar 

  35. 35.

    Bentall RHC (1986) Low-level pulsed radiofrequency fields and the treatment of soft tissue injuries. Bioelectrochem Bioenerg 16:531–548

    Article  Google Scholar 

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Conflict of interest

David G. Genecov received honoraria from BioElectronics Corporation for the study. Ian M. Rawe is a paid consultant for BioElectronics Corporation.

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Correspondence to Ian M. Rawe.

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Rawe, I.M., Lowenstein, A., Barcelo, C.R. et al. Control of Postoperative Pain with a Wearable Continuously Operating Pulsed Radiofrequency Energy Device: A Preliminary Study. Aesth Plast Surg 36, 458–463 (2012).

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  • Pain
  • Postoperative
  • Pulsed radiofrequency