Abstract
In recent years, lumpectomy combined with breast irradiation and chemotherapy, as a part of conservation therapy for breast cancer, has well-established results. Little has been published on reduction mammoplasty for breast-irradiated patients. These patients have increased risks of nipple necrosis, wound complications, and delayed healing. Breast reduction techniques that rely on minimum skin undermining combined with the use of buflomedil may prevent major postoperative complications in breast-irradiated patients. Buflomedil was administered intraoperatively and for 14 days after the procedure. The use of buflomedil in reduction mammaplasty for a previously irradiated breast patient has not been heretofore described. The case of a 58-year-old woman who underwent bilateral breast reduction after breast conservation therapy is reported.
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References
Spear SL, Burke JB, Forman D, Zuurbier RA, Berg CD (1998) Experience with reduction mammaplasty following breast conservation surgery and radiation therapy. Plast Reconstr Surg 102:1913–1916
Pitanguy I (1967) Surgical treatment of breast hypertrophy. Br J Plast Surg 20:78–85
Dias LC, Foutanos A, Carreiraõ S, Pitanguy I (1990) Influência do buflomedil na viabilidade do retalho de pele. Rev Bras Cir 80:49–55
Maurel A, Betrancourt JC, Van Frenkel R, Thuillez C (1995) Action of buflomedil on the cutaneous microcirculation studies by a cold provocation test: Multicenter, double-blind, placebo controlled trial. J Mal Vasc 20:127–133
Tuncer S, Bello-Rojas G, Ratiu C, Jackson IT (2006) Reduction mammaplasty in the previously radiated breast: Is it safe and does it interfere oncologically? Eur J Plast Surg 28:412–417
Benediktsson K, Perbeck L (1999) The influence of radiotherapy on skin circulation of the breast after subcutaneous mastectomy and immediate reconstruction. Br J Plast Surg 52:360–364
Toda N, Okunishi H, Okamura T, Miyazaki M (1983) Effects of buflomedil on isolated dog arteries. Angiology 32:699–704
Diamantopoulos EJ, Grigoriadou M, Ifanti G, Raptis SA (2001) Clinical and hemorheological effects of buflomedil in diabetic subjects with intermittent claudication. Int Angiol 20:337–344
Mauad RJ Jr, Shimizu MH, Mauad T, de Tolosa EM (2006) Buflomedil and pentoxifylline in the viability of dorsal cutaneous flaps of rats treated with nicotine. J Plast Reconstr Aesthet Surg 59:387–392
De Backer TL, Vander Stichele RH, Bogaert MG. Buflomedil for intermittent claudication. Cochrane Database Syst Rev(1):CD000988, 2001
Cassar K (2006) Intermittent claudication. BMJ 333:1002–1005
Alberti A, Valenti S, Gallo F, Petolillo M, Del Monte D (1994) Acute buflomedil intoxication: A life-threatening condition. Intensive Care Med 20:219–221
Legras A, Piquemal R, Furet Y, Dequin PF, Perrotin D (1996) Buflomedil poisoning: Five cases with cardiotoxicity. Intensive Care Med 22:57–61
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Sterodimas, A., Vargas, A., Radwanski, H.N. et al. The Use of Buflomedil in Reduction Mammaplasty for a Previously Irradiated Breast: A Case Report. Aesth Plast Surg 32, 383–385 (2008). https://doi.org/10.1007/s00266-007-9077-7
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DOI: https://doi.org/10.1007/s00266-007-9077-7