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Analysis of Laser Lipolysis Effects on Human Tissue Samples Obtained from Liposuction

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The use of the neodymium: yttrium-aluminum-garnet (Nd:YAG) laser as an auxiliary tool for lipoplasty has refined the traditional technique. The primary limitation of the traditional technique—large volume blood loss—is addressed by the use of the Nd:YAG laser. This report describe’s the technique of laser- assisted liposuction, then reviews and compares the histologic and morphometric effects with those of the traditional method.


The Nd:YAG laser was used to produce the desired injury to the adipose tissue after sufficient contact. Laser lipolysis was performed on the patient’s right flank in two different areas, with the application of 1,000 and 3,000 J of accumulated energy (∈), respectively. Subsequently, another cannula was introduced to suction the liquid content obtained by laser lipolysis. This tissue product was sent to the pathology laboratory for morphologic and morphometric analysis, and for comparison with material obtained from traditional lipoplasty performed on the left flank of the same patient.


The histopathologica examination of adipose tissue after laser lipolysis showed cell swelling and less bleeding, as compared with the traditional method. The morphometric analysis showed that the mean diameter of the major adipocye was 95.69 μm with laser lipolysis using 1,000 J (∈), 82.63 μm using 3,000 J (∈), and 84.54 μm with the traditional method


The traditional method produced less reversible cellular damage (swelling) than laser lipolysis using 1,000 J (∈). The area receiving 3,000 J (∈) showed major irreversible damage (cytoplasmatic retraction and disruption of membranes). For this reason, the mean diameter of the adipocyte was less.

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  1. Apfelberg DB. Results of multicenter study of laser-assisted-liposuction Clin Plast Surg 23:73–719, 1996

    Google Scholar 

  2. Apfelberg DB, Rosenthal S, Hunstad JP, Achauer B, Fodor PB. Progress on multicenter study of laser-assisted-liposuction Aes Plast Surg 18:259–264, 1994

    Article  CAS  Google Scholar 

  3. Badin AZD, Gondek LBE. Laserlipólise. In: Rejuvenescimento facial-cirurgia videoendoscópica e procedimento ancilares. Vol. 17. Liberate and Publisher Revinter: Rio de Janeiro, p. 318, 2003

  4. Badin AZD, Moraes LM, Gondek LBE, Chiaratti MG, Canta L. Laserlipólise: Flacidez sob controle Rev Soc Bras Laser em Medicina 22:77, 17–21, 2002

    Google Scholar 

  5. AZD Badin LM Moraes LBE Gondek MG Chiaratti L Canta (2002) ArticleTitleLaser lipolysis: Flaccidity under control Aesth Plast Surg 26 335–339 Occurrence Handle10.1007/s00266-002-1510-3

    Article  Google Scholar 

  6. Barcelos J: Lipoaspiração. In: Mélega JM, Zanini SA, Psillakis JM (eds.), Cirurgia plastica estética e reparadora. 2nd ed. Publisher Medsi, Brasil, vol. 83, p. 791, 1992

    Google Scholar 

  7. GW Commons B Halperin CC Chang (2001) ArticleTitleLarge-volume liposuction: The review of 631 consecutive cases over 12 years Plast Reconstr Surg 108 1753–1763 Occurrence Handle1:STN:280:DC%2BD3MnmsVCitw%3D%3D Occurrence Handle10.1097/00006534-200111000-00050 Occurrence Handle11711959

    Article  CAS  PubMed  Google Scholar 

  8. D‘Assumpção E: Lipoaspiraçãso com mínima depleção do paciente. In: Archangel A, Tournieux AAB (eds.) Atualização em cirurgia plástica estética-sociedade brasileira de cirurgia estética e reconstrutora regional SP. Vol. 53. São Paulo, Robe Editorial: p. 501, 1994

    Google Scholar 

  9. Dressel T. Laser lipoplasty: The preliminary report Lipoplasty Society Newslett 7:17, 1990

    Google Scholar 

  10. AS Goddio (1991) ArticleTitleSkin retraction following suction lipectomy by treatment site: The study of 500 procedures in 458 selected subjects Plast Reconstr Surg 87 66–75 Occurrence Handle1:STN:280:DyaK3M%2FnsV2htA%3D%3D Occurrence Handle10.1097/00006534-199101000-00012 Occurrence Handle1984283

    Article  CAS  PubMed  Google Scholar 

  11. FR Grippaudo RM Matarese AM Macone M Mazzochi N Scuderi (2000) ArticleTitleEffects of traditional and ultrasonic liposuction on adipose tissue: The biochemical approach Plast Reconstr surg 106 197–199 Occurrence Handle1:STN:280:DC%2BD3czjvVKqsQ%3D%3D Occurrence Handle10.1097/00006534-200007000-00037 Occurrence Handle10883634

    Article  CAS  PubMed  Google Scholar 

  12. Horibe ED, Hojibe K, Cruz MR: Lipoplastia tumescente pelo sistema peristáltico. In: Horibe EK (ed) Estética clínics Y cirúrgica. Liberate and Publisher Revinter: Rio de Janeiro, p. 265, 2000

    Google Scholar 

  13. A Matarasso O Hutchinson (2001) ArticleTitleLiposuction JAMA 285 266–268 Occurrence Handle1:STN:280:DC%2BD3M7kslaguw%3D%3D Occurrence Handle10.1001/jama.285.3.266 Occurrence Handle11176823

    Article  CAS  PubMed  Google Scholar 

  14. Toledo LS: Lipoplastia no Brasil. In: Horibe EK (ed) Estética clinica Y cirúrgica. Vol. 39. Liberate and Publisher Revinter: Rio de Janeiro, p. 265, 2000

    Google Scholar 

  15. Young VL and the Plastic Surgery Educational Foundation DATA Committee: Power-assisted lipoplasty. Plast Reconstr Surg 108:1429–1432, 2001

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Lúcia de Noronha.

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Badin, A.Z.E., Gondek, L.B., Garcia, M.J. et al. Analysis of Laser Lipolysis Effects on Human Tissue Samples Obtained from Liposuction. Aesth Plast Surg 29, 281–286 (2005).

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