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Nerve distribution to the human knee joint: anatomical and immunohistochemical study

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The nerve distribution to the knee joints was analyzed in 5 cadavers and 10 joint capsules specimens were resected during total knee arthroplasty. We found nerve fibers immunoreactive for anti-substance P antibody in the articular capsule. By confocal laser scanning microscopy, we evaluated the three-dimensional structures of the Ruffini’s corpuscles and the free nerve endings, both of which were immunoreactive for anti-protein gene product 9.5.


 Nous avons analysé la distribution des nerfs de l’articulation du genou en utilisant des cadavres (n=5) et des capsules d’articulation (n=10) réséquées pendant une arthroplastie totale du genou. Nous avons découvert des fibres de nerfs immunoréactives pour l’anticorps P de l’antisubstance dans la capsule d’articulation. Au moyen d’une microscopie scanographique par laser confocal, nous avons évalué les structures tridimensionnelles des corpuscules de Ruffini et les terminaisons des nerfs libres, lesquelles étaient immunoréactives pour le produit 9.5 du gëne antiprotéine.

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Accepted: 6 January 2000

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Hirasawa, Y., Okajima, S., Ohta, M. et al. Nerve distribution to the human knee joint: anatomical and immunohistochemical study. International Orthopaedics SICOT 24, 1–4 (2000).

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