Skip to main content


Log in

Nephrotoxicity by dicloxacillin and gentamicin in 163 patients with intertrochanteric hip fractures

  • Original Paper
  • Published:
International Orthopaedics Aims and scope Submit manuscript


Of 163 patients with intertrochanteric hip fractures 87 received 2 g dicloxacillin and 240 mg of gentamicin preoperatively, and 76 patients had no antibiotic prophylaxis. Preoperative antibiotic prophylaxis was not shown to have any significant effect on wound infections. However, 16 reversible and 1 irreversible cases of kidney toxicity were found among patients receiving antibiotic prophylaxis, whereas there were only four cases of reversible kidney damage among the patients not receiving antibiotics.


 Parmi 163 patients avec des fractures intertrochantériennes, 87 patients avaient reçu en préopératoire 2 g Dicloxacilline et 240 mg Gentamicine. 76 patients n’avaient reçu aucune prophylaxie antibiotique. La prophylaxie préopératoire contre les infections n’a montré aucun effet significatif. Cependant dans le groupe avec prophylaxie, 17 affections rénales ont été observées, dont 16 réversibles et 1 irréversible. Parmi les patients n’ayant reçu aucune prophylaxie antibiotique 4 affections rénales réversibles ont été observées.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Author information

Authors and Affiliations


Additional information

Accepted: 29 November 1999

Rights and permissions

Reprints and permissions

About this article

Cite this article

Solgaard, L., Tuxoe, J., Mafi, M. et al. Nephrotoxicity by dicloxacillin and gentamicin in 163 patients with intertrochanteric hip fractures. International Orthopaedics SICOT 24, 155–157 (2000).

Download citation

  • Issue Date:

  • DOI: