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Is three-dimension-printed mesh scaffold an alternative to reconstruct cavity bone defects near joints?

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Abstract

Purpose

Reconstruction of cavity bone defects after curettage of benign bone tumours around the joint remains challenging. We designed a novel 3D-printed mesh scaffold as a substitute for bone cement, aiming to support the articular surface, protect the subchondral bone, and reduce complication rates.

Methods

We retrospectively analyzed seven patients who received curettage and reconstruction using a 3D-printed mesh scaffold between January 2020 and June 2021. Pain and function were evaluated using the 10-cm Visual Analogue Scale (VAS) score and the 1993 version of the Musculoskeletal Tumor Society (MSTS-93) score. Radiographs were used to evaluate articular surface supporting, subchondral bone protection, and complications.

Results

The median functional MSTS-93 and VAS scores were both improved after surgery, and the median 3D-printed mesh scaffold volume was smaller than the median defect volume. Articular surface supporting, subchondral bone preservation, and osteogenesis were observed post-operatively. No related complications were observed during the last follow-up.

Conclusions

The 3D-printed mesh scaffold provided sufficient mechanical support for the articular surface and protected the subchondral bone. We recommended the 3D-printed mesh structure as an alternative to repair cavity bone defects around joints.

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Data availability

All data is available.

Code availability

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Funding

This work was supported by the Science and Technology Research Program of Sichuan Province (2020YFS0036), 1·3·5 project for disciplines of excellence, West China Hospital, Sichuan University (ZYJC18017), 1·3·5 project for disciplines of excellence, West China Hospital, Sichuan University (ZYJC18036), the Project funded by China Postdoctoral Science Foundation (2021M702342).

Author information

Author notes

  1. Taojun Gong and Minxun Lu contributed equally to this work.

Authors and Affiliations

  1. Department of Orthopedics, Orthopaedic Research Institute, West China Hospital, Sichuan University, Chengdu, People’s Republic of China

    Taojun Gong, Minxun Lu, Jie Wang, Yuqi Zhang, Yitian Wang, Zhuangzhuang Li, Li Min, Yi Luo, Yong Zhou & Chongqi Tu

  2. Sichuan Model Worker and Craftsman Talent Innovation Research Studio, West China Hospital, Sichuan University, Chengdu, People’s Republic of China

    Taojun Gong, Minxun Lu, Jie Wang, Yuqi Zhang, Yitian Wang, Zhuangzhuang Li, Li Min, Yi Luo, Yong Zhou & Chongqi Tu

Authors
  1. Taojun Gong
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  2. Minxun Lu
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  3. Jie Wang
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  4. Yuqi Zhang
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  7. Li Min
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Contributions

TJG and MXL contributed equally to this work and are co-first authors. TJG analyzed and interpreted the data. TJG and MXL wrote and edited the manuscript. JW, YQZ YTW, ZZL, YL, and LM were involved in the design of the prosthesis and reviewed the manuscript. YZ and CQT supervised and reviewed the manuscript. All authors contributed to the article and approved the submitted version.

Corresponding authors

Correspondence to Yong Zhou or Chongqi Tu.

Ethics declarations

Ethics approval

This study was performed in accordance with the Declaration of Helsinki and was authorized by the Ethics Committee of West China Hospital. All patients’ parents signed the informed consent form before surgery and provided consent to publish and report individual clinical data.

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Written informed consent of off-label treatment was collected from all patients prior to treatment.

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Not applicable.

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The authors declare that no competing interests.

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Gong, T., Lu, M., Wang, J. et al. Is three-dimension-printed mesh scaffold an alternative to reconstruct cavity bone defects near joints?. International Orthopaedics (SICOT) 47, 631–639 (2023). https://doi.org/10.1007/s00264-022-05684-8

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  • DOI: https://doi.org/10.1007/s00264-022-05684-8

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