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Acetabular screws do not improve early revision rates in primary total hip arthroplasty. An instrumented registry analysis

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Abstract

Background

Initial stability of uncemented acetabular components in total hip arthroplasty (THA) is important for osseointegration and potentially enhanced by screw fixation. We used Australian Orthopaedic Association National Joint Replacement Registry data to determine whether screw usage influences uncemented acetabular component survival.

Methods

Primary THA with uncemented acetabular components performed for osteoarthritis from 1999 to 2018 was included. Survivorship was calculated using Kaplan-Meier estimates of cumulative percent revision (CPR). Comparisons used Cox proportional hazards method. An instrumental variable analysis adjusted for surgeon preference for screws as a confounding factor was used.

Results

Three hundred thirty thousand one hundred ninety-two THAs were included (31.8% with screws, 68.2% without). Two hundred twenty thousand six hundred seven were included in the instrumental variable analysis. Revision rate of acetabular components (all causes) was higher with screws during the first six years (hazard ratio (HR) = 1.45 (95% CI 1.34, 1.57), p < 0.001) and lower thereafter (HR = 0.81 (95% CI 0.67, 0.98), p = 0.027). Revision rate of acetabular components for loosening was higher with screws over the entire study period (HR = 1.73 (95% CI 1.51, 1.98), p < 0.001). Overall THA revision rate was higher with screws during the first six years (HR = 1.20 (95% CI 1.15, 1.26), p < 0.001) but lower thereafter (HR = 0.89 (95% CI 0.81, 0.98), p = 0.020). Revision rate for dislocation was higher with screws over the entire period (HR = 1.16 (95% CI 1.06, 1.26), p < 0.001). Instrumental variable analysis revealed higher revision rates with acetabular screws in the first six years. (HR = 1.18 (95% CI 1.09–1.29), p < 0.001).

Conclusion

Screws did not confer a protective effect against acetabular loosening and were not associated with long-term negative consequences.

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Data availability

Data was extracted from the AOANJRR database.

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Acknowledgements

We acknowledge the Australian Orthopaedic Association National Joint Replacement Registry for the access to the data used in this study.

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Authors and Affiliations

Authors

Contributions

MN: manuscript preparation and editing

DGC: project conception and advice and manuscript editing

PLL: manuscript editing and data requisition from AOANJRR

ARC: statistical analysis

LBS: manuscript editing and advice

Corresponding author

Correspondence to Mary Nugent.

Ethics declarations

Ethics approval

The AOANJRR is approved by the Australian Federal Government as a Declaration of Quality Assurance Activity under section 124X of the Australian Federal Health Insurance Act, 1973. All investigations were conducted in accordance with ethical principles of research (the Helsinki Declaration II).

Consent to participate

All patients consented to data collection by the AOANJRR (anonymized analysis).

Consent to publish

Consent for AOANJRR includes use of database in published reports and scientific papers.

Conflict of interest

  • Financial interests

    DGC received royalties from Smith & Nephew (unrelated work) and research support from Stryker (unrelated work). LBS received research support funding from Zimmer Biomet (unrelated work). PL is a paid director of the Australian Orthopaedic Association National Joint Replacement Registry. MN and AC have no financial interests.

  • Non-financial interests

    LBS holds positions on the editorial board of the Journal of Clinical Medicine and is a committee member of the Australian and New Zealand Orthopaedic Research Society.

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Nugent, M., Campbell, D.G., Lewis, P.L. et al. Acetabular screws do not improve early revision rates in primary total hip arthroplasty. An instrumented registry analysis. International Orthopaedics (SICOT) 45, 593–604 (2021). https://doi.org/10.1007/s00264-021-04949-y

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  • DOI: https://doi.org/10.1007/s00264-021-04949-y

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