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Quality of life of patients with osteonecrosis of the femoral head: a multicentre study

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Abstract

Purpose

Quality-of-life (QOL) assessments in patients with osteonecrosis of the femoral head (ONFH) have rarely been reported. This multicentre study aimed to elucidate the relationship between disease severity, including necrotic lesion type and radiological staging, and QOL, as well as between patients’ characteristics and QOL.

Methods

Two hundred seventy-four patients with ONFH (108 females, 166 males; median age, 46 years) were asked to complete self-assessment QOL questionnaires including the Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire, Oxford Hip Score, and SF-12v2.

Results

Patients with large necrotic lesion type or collapsed ONFH had low QOL scores. Among patients with non-collapsed lesions, patients with alcohol-associated ONFH had lower QOL scores than those with steroid-associated ONFH, those with bilateral ONFH had lower mental scores, and male patients had worse social condition scores. Among patients with collapsed lesions, middle-aged patients exhibited lower mental QOL, and a strong correlation was observed between social activity and mental health.

Conclusion

Collapsed ONFH was associated with low QOL scores. Among patients with non-collapsed lesions, alcohol-associated ONFH, bilateral disease, and male sex were linked to low QOL scores.

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Abbreviations

JIC:

Japanese Investigating Committee

JHEQ:

Japanese Orthopaedic Association Hip-Disease Evaluation Questionnaire

OHS:

Oxford Hip Score

PCS:

Physical component summary

MCS:

Mental component summary

RCS:

Role/social component summary

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Acknowledgements

We thank Prof Wakaba Fukushima and Mr. Kazuya Ito for their helpful advices. We also thank Drs Hiromasa Tanino, Toshiyuki Tateiwa, Yusuke Kubo, Daisuke Inoue, Satoshi Kubota, Hiroyuki Ike, Yohei Naito, Masaki Takao, and Hidetoshi Hamada for their helpful support.

Funding

The principal investigator (NS) of the Japanese Investigation Committee under the auspices of the Ministry of Health Labour and Welfare received a research grant from the Ministry of Health and Welfare of Japan (Research on Measures for Intractable Diseases).

Author information

Authors and Affiliations

  1. Department of International Health, Graduate School of Health Science, Kobe University, 7-10-2, Tomogaoka, Suma-Ku, Kobe, 654-0142, Japan

    Yuko Uesugi

  2. Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka University, 2-2, Yamadaoka, Suita, 565-0871, Japan

    Takashi Sakai

  3. Department of Orthopaedic Surgery, Graduate School of Medicine, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, 466-8550, Japan

    Taisuke Seki

  4. Department of Orthopaedic Surgery, Graduate School of Medicine, Kobe University, 7-5-1, Kusunoki-Cho, Chuo-Ku, Kobe, 650-0017, Japan

    Shinya Hayashi

  5. Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1-8-1, Inohana, Chuo-Ku, Chiba, 260-8670, Japan

    Junichi Nakamura

  6. Department of Orthopaedic Surgery, Graduate School of Medicine, Yokohama City University, 3-9, Fukuura, Kanazawa-Ku, Yokohama, 236-0004, Japan

    Yutaka Inaba

  7. Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-Ku, Sapporo, 060-8638, Japan

    Daisuke Takahashi

  8. Department of Orthopaedic Surgery, Faculty of Medicine, Yamagata University, 2-2-2, Iida-Nishi, Yamagata, 990-9585, Japan

    Kan Sasaki

  9. Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan

    Goro Motomura

  10. Department of Orthopaedic Surgery, Graduate School of Medicine, Ehime University, Shitsukawa, Toon, 791-0295, Japan

    Naohiko Mashima

  11. Department of Orthopaedic Surgery, Graduate School of Medical science, Kanazawa University, 13-1, Takaramachi, Kanazawa, 920-8641, Japan

    Tamon Kabata

  12. Department of Orthopaedic Surgery, Graduate School of Medicine, Mie University, 2-174, Edobashi, Tsu, 514-8507, Japan

    Akihiro Sudo

  13. Department of Orthopaedic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-Ku, 113-8510, Japan

    Tetsuya Jinno

  14. Department of Orthopaedic Surgery, Kansai-Rosai Hospital, 3-1-69, Inabaso, Amagasaki, 660-8511, Japan

    Wataru Ando

  15. Department of Orthopaedic Surgery, Sapporo Medical University, Minami-1, Nishi-17, Chuo-ku, Sapporo, 060-8556, Japan

    Satoshi Nagoya

  16. Department of Orthopaedic Surgery, School of Medicine, Tokyo Medical University, 6-7-1, Nishishinjyuku, Shinjyuku-Ku, Tokyo, 160-0023, Japan

    Kengo Yamamoto

  17. Department of Orthopaedic Surgery, Graduate School of Medicine, University of the Ryukus, 207 Uehara, Nishihara, Nakagami-Gun, 903-0215, Japan

    Satoshi Nakasone

  18. Department of Orthopaedic Surgery, School of Medicine, Asahikawa Medical University, 1-1-1, Midorigaoka-Higahi 2jou, Asahikawa, 078-8510, Japan

    Hiroshi Ito

  19. Department of Orthopaedic Surgery, Faculty of Medicine, Fukuoka University, 7-45-1, Nanakuma, Jounan-Ku, Fukuoka, 814-0180, Japan

    Takuaki Yamamoto

  20. Department of Orthopaedic Medical Engineering, Graduate School of Medicine, Osaka University, 2-2, Yamadaoka, Suita, 565-0870, Japan

    Nobuhiko Sugano

Authors
  1. Yuko Uesugi
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  2. Takashi Sakai
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  3. Taisuke Seki
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  4. Shinya Hayashi
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  5. Junichi Nakamura
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  6. Yutaka Inaba
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  7. Daisuke Takahashi
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  8. Kan Sasaki
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  9. Goro Motomura
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  10. Naohiko Mashima
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  11. Tamon Kabata
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  12. Akihiro Sudo
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  13. Tetsuya Jinno
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  14. Wataru Ando
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  15. Satoshi Nagoya
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  16. Kengo Yamamoto
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  17. Satoshi Nakasone
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  18. Hiroshi Ito
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  19. Takuaki Yamamoto
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  20. Nobuhiko Sugano
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Corresponding author

Correspondence to Takashi Sakai.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

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Uesugi, Y., Sakai, T., Seki, T. et al. Quality of life of patients with osteonecrosis of the femoral head: a multicentre study. International Orthopaedics (SICOT) 42, 1517–1525 (2018). https://doi.org/10.1007/s00264-018-3897-8

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  • DOI: https://doi.org/10.1007/s00264-018-3897-8

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