International Orthopaedics

, Volume 42, Issue 4, pp 867–874 | Cite as

Two-stage revision of infected shoulder arthroplasty using prosthesis of antibiotic-loaded acrylic cement: minimum three-year follow-up

  • Sung Hyun Lee
  • Se Jin Kim
  • Seng Hwan Kook
  • Jeong Woo Kim
Original Paper



This study aimed to evaluate the clinical outcomes and persistent infection rate of two-stage revision of infected shoulder arthroplasty.


We enrolled 12 patients who developed an infection after undergoing shoulder arthroplasty between January 2009 and January 2014. They underwent a two-stage revision with PROSTALAC implantation and shoulder re-implantation in the first- and second-stage surgery, respectively. The mean follow-up period was 40.88 months (range, 36–52 months). After the second-stage re-implantation, clinical scores, erythrocyte sedimentation rate, as well as C-reactive protein level were evaluated, and the presence of re-infection and complications were analyzed.


Infection was improved in all the cases after PROSTALAC insertion. The mean range of motion of forward elevation, external rotation, and internal rotation at the final follow-up after the second-stage re-implantation were 81.67°, 40.42°, and 16.67° (vertebral level), respectively. The mean visual analog scale score improved from 7.08 points before surgery to 2.33 points after surgery. The Modified American Shoulder and Elbow Surgeons score improved from 32.25 before surgery to 64.17 after surgery (P < 0.05). The Constant shoulder score also improved from 30.92 before surgery to 66.08 after surgery (P < 0.05). Infection had not recurred until the final follow-up. However, dislocation and separation of components were found in two patients who needed a structural allograft because of segmental bone defects.


Using PROSTALAC in two-stage revision arthroplasty is effective for infection control and produced good clinical outcomes after second-stage shoulder re-implantation. However, cases involving segmental bone defects require additional precautions in maintaining the appropriate tension and height to prevent complications.


Shoulder arthroplasty Infected arthroplasty Two-stage surgery Prosthesis of antibiotic-loaded acrylic cement 



This study was supported by a Wonkwang University research grant 2018.


There is no funding source.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

Institutional review board approval was obtained before starting the study.


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Copyright information

© SICOT aisbl 2017

Authors and Affiliations

  • Sung Hyun Lee
    • 1
  • Se Jin Kim
    • 1
  • Seng Hwan Kook
    • 1
  • Jeong Woo Kim
    • 1
  1. 1.Department of Orthopedic Surgery, School of MedicineWonkwang University HospitalIksanRepublic of Korea

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