Skip to main content
Log in

Risk factors of recompression of cemented vertebrae after kyphoplasty for osteoporotic vertebral compression fractures

  • Original Paper
  • Published:
International Orthopaedics Aims and scope Submit manuscript

Abstract

Purpose

To evaluate the risk factors correlated with loss of cemented vertebral body height after kyphoplasty in patients with osteoporotic vertebral compression fractures.

Methods

Thirty-four consecutive patients with single-level osteoporotic vertebral compression fractures who underwent kyphoplasty in the Affiliated Hospital of Jiangsu University between January 2012 and August 2014 were retrospectively analysed. Eight independent variables (age, gender, body mass index, pre-operative T-score in bone mineral density, the volume of polymethylmethacrylate injected, pre-operatively vertebral body height, the restoration of body height and the distance between polymethylmethacrylate and endplate) were assessed. The recompression of body height was the dependent variable. Multivariate linear regression analyses were used to determine the factors associated with recompression of body height.

Results

Multiple linear regression analyses indicated that the recompression of cemented vertebral body height was correlated with the distance between polymethylmethacrylate and endplate (P = 0.008, b’ = 0.489). The final multiple linear regression model, which included only the distance between polymethylmethacrylate and endplate, resulted in a formula that accounted for 41.02 % of the recompression of body height.

Conclusions

The distance between polymethylmethacrylate and endplate is an important risk factor of recompression of cemented vertebrae after kyphoplasty for patients with osteoporotic vertebral compression fractures.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Kim MJ, Lindsey DP, Hannibal M, Alamin TF (2006) Vertebroplasty versus kyphoplasty: biomechanical behavior under repetitive loading conditions. Spine (Phila Pa 1976) 31(18):2079–2084. doi:10.1097/01.brs.0000231714.15876.76

    Article  Google Scholar 

  2. Krappinger D, Kastenberger TJ, Schmid R (2012) Augmented posterior instrumentation for the treatment of osteoporotic vertebral body fractures. Oper Orthop Traumatol 24(1):4–12. doi:10.1007/s00064-011-0098-7

    Article  CAS  PubMed  Google Scholar 

  3. Zou D, Zhang K, Ren Y (2015) Therapeutic effects of PKP on chronic painful osteoporotic vertebral compression fractures with or without intravertebral cleft. Int J Clin Exp Med 8(9):15780–15786

    PubMed  PubMed Central  Google Scholar 

  4. Lee SK, Lee SH, Yoon SP, Lee YT, Jang G, Lim SY, Lee HM, Moon SH, Song KS (2014) Quality of life comparison between vertebroplasty and kyphoplasty in patients with osteoporotic vertebral fractures. Asian Spine J 8(6):799–803

    Article  PubMed  PubMed Central  Google Scholar 

  5. Drampalos E, Nikolopoulos K, Baltas C, Balanika A, Galanos A, Papaioannou N, Pneumaticos S (2015) Vertebral fracture assessment: current research status and application in patients with kyphoplasty. World J Orthop 6(9):680–687. doi:10.5312/wjo.v6.i9.680

    Article  PubMed  PubMed Central  Google Scholar 

  6. Cummings SR, Melton LJ (2002) Epidemiology and outcomes of osteoporotic fractures. Lancet 359(9319):1761–1767. doi:10.1016/S0140-6736(02)08657-9

    Article  PubMed  Google Scholar 

  7. Martincic D, Brojan M, Kosel F, Stern D, Vrtovec T, Antolic V, Vengust R (2015) Minimum cement volume for vertebroplasty. Int Orthop 39(4):727–733. doi:10.1007/s00264-014-2620-7

    Article  PubMed  Google Scholar 

  8. Zhu SY, Zhong ZM, Wu Q, Chen JT (2016) Risk factors for bone cement leakage in percutaneous vertebroplasty: a retrospective study of four hundred and eighty five patients. Int Orthop. doi:10.1007/s00264-015-3102-2

    Google Scholar 

  9. Takahara K, Kamimura M, Moriya H, Ashizawa R, Koike T, Hidai Y, Ikegami S, Nakamura Y, Kato H (2016) Risk factors of adjacent vertebral collapse after percutaneous vertebroplasty for osteoporotic vertebral fracture in postmenopausal women. BMC Musculoskelet Disord 17(1):12. doi:10.1186/s12891-016-0887-0

    Article  PubMed  PubMed Central  Google Scholar 

  10. Zhang L, Liu Z, Wang J, Feng X, Yang J, Tao Y, Zhang S (2015) Unipedicular versus bipedicular percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a prospective randomized study. BMC Musculoskelet Disord 16:145. doi:10.1186/s12891-015-0590-6

    Article  PubMed  PubMed Central  Google Scholar 

  11. Balkarli H, Demirtas H, Kilic M, Ozturk I (2015) Treatment of osteoporotic vertebral compression fractures with percutaneous vertebroplasty under local anesthesia: clinical and radiological results. Int J Clin Exp Med 8(9):16287–16293

    PubMed  PubMed Central  Google Scholar 

  12. Civelek E, Cansever T, Yilmaz C, Kabatas S, Gulsen S, Aydemir F, Altiotanors N, Caner H (2014) The retrospective analysis of the effect of balloon kyphoplasty to the adjacent-segment fracture in 171 patients. J Spinal Disord Tech 27(2):98–104

    Article  PubMed  Google Scholar 

  13. Atalay B, Caner H, Gokce C, Altinors N (2005) Kyphoplasty: 2 years of experience in a neurosurgery department. Surg Neurol 64(Suppl 2):S72–76. doi:10.1016/j.surneu.2005.07.039

    Article  PubMed  Google Scholar 

  14. Lieberman I, Reinhardt MK (2003) Vertebroplasty and kyphoplasty for osteolytic vertebral collapse. Clin Orthop Relat Res (415 Suppl):S176–186. doi:10.1097/01.blo.0000093841.72468.a8

  15. Zhai W, Jia Y, Wang J, Cheng L (2015) The clinical application and efficacy of percutaneous kyphoplasty via unilateral pedicular approach guided by CT image measurement. Int J Clin Exp Med 8(11):20861–20868

    PubMed  PubMed Central  Google Scholar 

  16. Chang X, Lv YF, Chen B, Li HY, Han XB, Yang K, Zhang W, Zhou Y, Li CQ (2015) Vertebroplasty versus kyphoplasty in osteoporotic vertebral compression fracture: a meta-analysis of prospective comparative studies. Int Orthop 39(3):491–500. doi:10.1007/s00264-014-2525-5

    Article  PubMed  Google Scholar 

  17. Niu J, Zhou H, Meng Q, Shi J, Meng B, Yang H (2015) Factors affecting recompression of augmented vertebrae after successful percutaneous balloon kyphoplasty: a retrospective analysis. Acta Radiol 56(11):1380–1387. doi:10.1177/0284185114556016

    Article  PubMed  Google Scholar 

  18. Liu HX, Xu C, Shang P, Shen Y, Xu HZ (2014) The effect of postural correction and subsequent balloon inflation in deformity correction of acute osteoporotic vertebral fractures. J Korean Neurosurg Soc 55(6):337–342. doi:10.3340/jkns.2014.55.6.337

    Article  PubMed  PubMed Central  Google Scholar 

  19. Boonen S, Van Meirhaeghe J, Bastian L, Cummings SR, Ranstam J, Tillman JB, Eastell R, Talmadge K, Wardlaw D (2011) Balloon kyphoplasty for the treatment of acute vertebral compression fractures: 2-year results from a randomized trial. J Bone Miner Res Off J Am Soc Bone Miner Res 26(7):1627–1637. doi:10.1002/jbmr.364

    Article  Google Scholar 

  20. Chen C, Li D, Wang Z, Li T, Liu X, Zhong J (2016) Safety and efficacy studies of vertebroplasty, kyphoplasty, and mesh-container-plasty for the treatment of vertebral compression fractures: preliminary report. PLoS One 11(3):e0151492. doi:10.1371/journal.pone.0151492

    Article  PubMed  PubMed Central  Google Scholar 

  21. Zhai W, Jia Y, Wang J, Cheng L, Zeng Z, Yu Y, Chen L (2015) The clinical effect of percutaneous kyphoplasty for the treatment of multiple osteoporotic vertebral compression fractures and the prevention of new vertebral fractures. Int J Clin Exp Med 8(8):13473–13481

    PubMed  PubMed Central  Google Scholar 

  22. Kanayama M, Oha F, Iwata A, Hashimoto T (2015) Does balloon kyphoplasty improve the global spinal alignment in osteoporotic vertebral fracture? Int Orthop 39(6):1137–1143. doi:10.1007/s00264-015-2737-3

    Article  PubMed  Google Scholar 

  23. Xiao H, Yang J, Feng X, Chen P, Li Y, Huang C, Liang Y, Chen H (2015) Comparing complications of vertebroplasty and kyphoplasty for treating osteoporotic vertebral compression fractures: a meta-analysis of the randomized and non-randomized controlled studies. Eur J Orthop Surg Traumatol 25(Suppl 1):S77–85. doi:10.1007/s00590-014-1502-4

    Article  PubMed  Google Scholar 

  24. Abduljabbar FH, Al-Jurayyan A, Alqahtani S, Sardar ZM, Saluja RS, Ouellet J, Weber M, Steffen T, Beckman L, Jarzem P (2015) Does balloon kyphoplasty deliver more cement safely into osteoporotic vertebrae with compression fractures compared with vertebroplasty? A study in vertebral analogues. Glob Spine J 5(4):300–307. doi:10.1055/s-0035-1546818

    Article  Google Scholar 

  25. Kim YY, Rhyu KW (2010) Recompression of vertebral body after balloon kyphoplasty for osteoporotic vertebral compression fracture. Eur Spine J 19(11):1907–1912. doi:10.1007/s00586-010-1479-6

    Article  PubMed  PubMed Central  Google Scholar 

  26. Ha KY, Kim KW, Kim YH, Oh IS, Park SW (2010) Revision surgery after vertebroplasty or kyphoplasty. Clin Orthop Surg 2(4):203–208. doi:10.4055/cios.2010.2.4.203

    Article  PubMed  PubMed Central  Google Scholar 

  27. Kruger A, Oberkircher L, Kratz M, Baroud G, Becker S, Ruchholtz S (2012) Cement interdigitation and bone-cement interface after augmenting fractured vertebrae: a cadaveric study. Int J Spine Surg 6:115–123. doi:10.1016/j.ijsp.2012.02.005

    Article  PubMed  PubMed Central  Google Scholar 

  28. Pesenti S, Blondel B, Peltier E, Adetchessi T, Dufour H, Fuentes S (2014) Percutaneous cement-augmented screws fixation in the fractures of the aging spine: is it the solution? BioMed Res Int 2014:610675. doi:10.1155/2014/610675

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Dapeng Li.

Ethics declarations

Funding

This research was supported by the Jiangsu Provincial Special Program of Medical Science (BL2012004) and Clinical Research Foundation of Affiliated Hospital of Jiangsu University (JDFYRC-2013018). The funder had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required.

Additional information

Dapeng Li and Yan Wu contributed equally to this work.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, D., Wu, Y., Huang, Y. et al. Risk factors of recompression of cemented vertebrae after kyphoplasty for osteoporotic vertebral compression fractures. International Orthopaedics (SICOT) 40, 1285–1290 (2016). https://doi.org/10.1007/s00264-016-3203-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00264-016-3203-6

Keywords

Navigation