Abstract
Purpose
To evaluate the risk factors correlated with loss of cemented vertebral body height after kyphoplasty in patients with osteoporotic vertebral compression fractures.
Methods
Thirty-four consecutive patients with single-level osteoporotic vertebral compression fractures who underwent kyphoplasty in the Affiliated Hospital of Jiangsu University between January 2012 and August 2014 were retrospectively analysed. Eight independent variables (age, gender, body mass index, pre-operative T-score in bone mineral density, the volume of polymethylmethacrylate injected, pre-operatively vertebral body height, the restoration of body height and the distance between polymethylmethacrylate and endplate) were assessed. The recompression of body height was the dependent variable. Multivariate linear regression analyses were used to determine the factors associated with recompression of body height.
Results
Multiple linear regression analyses indicated that the recompression of cemented vertebral body height was correlated with the distance between polymethylmethacrylate and endplate (P = 0.008, b’ = 0.489). The final multiple linear regression model, which included only the distance between polymethylmethacrylate and endplate, resulted in a formula that accounted for 41.02 % of the recompression of body height.
Conclusions
The distance between polymethylmethacrylate and endplate is an important risk factor of recompression of cemented vertebrae after kyphoplasty for patients with osteoporotic vertebral compression fractures.
Similar content being viewed by others
References
Kim MJ, Lindsey DP, Hannibal M, Alamin TF (2006) Vertebroplasty versus kyphoplasty: biomechanical behavior under repetitive loading conditions. Spine (Phila Pa 1976) 31(18):2079–2084. doi:10.1097/01.brs.0000231714.15876.76
Krappinger D, Kastenberger TJ, Schmid R (2012) Augmented posterior instrumentation for the treatment of osteoporotic vertebral body fractures. Oper Orthop Traumatol 24(1):4–12. doi:10.1007/s00064-011-0098-7
Zou D, Zhang K, Ren Y (2015) Therapeutic effects of PKP on chronic painful osteoporotic vertebral compression fractures with or without intravertebral cleft. Int J Clin Exp Med 8(9):15780–15786
Lee SK, Lee SH, Yoon SP, Lee YT, Jang G, Lim SY, Lee HM, Moon SH, Song KS (2014) Quality of life comparison between vertebroplasty and kyphoplasty in patients with osteoporotic vertebral fractures. Asian Spine J 8(6):799–803
Drampalos E, Nikolopoulos K, Baltas C, Balanika A, Galanos A, Papaioannou N, Pneumaticos S (2015) Vertebral fracture assessment: current research status and application in patients with kyphoplasty. World J Orthop 6(9):680–687. doi:10.5312/wjo.v6.i9.680
Cummings SR, Melton LJ (2002) Epidemiology and outcomes of osteoporotic fractures. Lancet 359(9319):1761–1767. doi:10.1016/S0140-6736(02)08657-9
Martincic D, Brojan M, Kosel F, Stern D, Vrtovec T, Antolic V, Vengust R (2015) Minimum cement volume for vertebroplasty. Int Orthop 39(4):727–733. doi:10.1007/s00264-014-2620-7
Zhu SY, Zhong ZM, Wu Q, Chen JT (2016) Risk factors for bone cement leakage in percutaneous vertebroplasty: a retrospective study of four hundred and eighty five patients. Int Orthop. doi:10.1007/s00264-015-3102-2
Takahara K, Kamimura M, Moriya H, Ashizawa R, Koike T, Hidai Y, Ikegami S, Nakamura Y, Kato H (2016) Risk factors of adjacent vertebral collapse after percutaneous vertebroplasty for osteoporotic vertebral fracture in postmenopausal women. BMC Musculoskelet Disord 17(1):12. doi:10.1186/s12891-016-0887-0
Zhang L, Liu Z, Wang J, Feng X, Yang J, Tao Y, Zhang S (2015) Unipedicular versus bipedicular percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a prospective randomized study. BMC Musculoskelet Disord 16:145. doi:10.1186/s12891-015-0590-6
Balkarli H, Demirtas H, Kilic M, Ozturk I (2015) Treatment of osteoporotic vertebral compression fractures with percutaneous vertebroplasty under local anesthesia: clinical and radiological results. Int J Clin Exp Med 8(9):16287–16293
Civelek E, Cansever T, Yilmaz C, Kabatas S, Gulsen S, Aydemir F, Altiotanors N, Caner H (2014) The retrospective analysis of the effect of balloon kyphoplasty to the adjacent-segment fracture in 171 patients. J Spinal Disord Tech 27(2):98–104
Atalay B, Caner H, Gokce C, Altinors N (2005) Kyphoplasty: 2 years of experience in a neurosurgery department. Surg Neurol 64(Suppl 2):S72–76. doi:10.1016/j.surneu.2005.07.039
Lieberman I, Reinhardt MK (2003) Vertebroplasty and kyphoplasty for osteolytic vertebral collapse. Clin Orthop Relat Res (415 Suppl):S176–186. doi:10.1097/01.blo.0000093841.72468.a8
Zhai W, Jia Y, Wang J, Cheng L (2015) The clinical application and efficacy of percutaneous kyphoplasty via unilateral pedicular approach guided by CT image measurement. Int J Clin Exp Med 8(11):20861–20868
Chang X, Lv YF, Chen B, Li HY, Han XB, Yang K, Zhang W, Zhou Y, Li CQ (2015) Vertebroplasty versus kyphoplasty in osteoporotic vertebral compression fracture: a meta-analysis of prospective comparative studies. Int Orthop 39(3):491–500. doi:10.1007/s00264-014-2525-5
Niu J, Zhou H, Meng Q, Shi J, Meng B, Yang H (2015) Factors affecting recompression of augmented vertebrae after successful percutaneous balloon kyphoplasty: a retrospective analysis. Acta Radiol 56(11):1380–1387. doi:10.1177/0284185114556016
Liu HX, Xu C, Shang P, Shen Y, Xu HZ (2014) The effect of postural correction and subsequent balloon inflation in deformity correction of acute osteoporotic vertebral fractures. J Korean Neurosurg Soc 55(6):337–342. doi:10.3340/jkns.2014.55.6.337
Boonen S, Van Meirhaeghe J, Bastian L, Cummings SR, Ranstam J, Tillman JB, Eastell R, Talmadge K, Wardlaw D (2011) Balloon kyphoplasty for the treatment of acute vertebral compression fractures: 2-year results from a randomized trial. J Bone Miner Res Off J Am Soc Bone Miner Res 26(7):1627–1637. doi:10.1002/jbmr.364
Chen C, Li D, Wang Z, Li T, Liu X, Zhong J (2016) Safety and efficacy studies of vertebroplasty, kyphoplasty, and mesh-container-plasty for the treatment of vertebral compression fractures: preliminary report. PLoS One 11(3):e0151492. doi:10.1371/journal.pone.0151492
Zhai W, Jia Y, Wang J, Cheng L, Zeng Z, Yu Y, Chen L (2015) The clinical effect of percutaneous kyphoplasty for the treatment of multiple osteoporotic vertebral compression fractures and the prevention of new vertebral fractures. Int J Clin Exp Med 8(8):13473–13481
Kanayama M, Oha F, Iwata A, Hashimoto T (2015) Does balloon kyphoplasty improve the global spinal alignment in osteoporotic vertebral fracture? Int Orthop 39(6):1137–1143. doi:10.1007/s00264-015-2737-3
Xiao H, Yang J, Feng X, Chen P, Li Y, Huang C, Liang Y, Chen H (2015) Comparing complications of vertebroplasty and kyphoplasty for treating osteoporotic vertebral compression fractures: a meta-analysis of the randomized and non-randomized controlled studies. Eur J Orthop Surg Traumatol 25(Suppl 1):S77–85. doi:10.1007/s00590-014-1502-4
Abduljabbar FH, Al-Jurayyan A, Alqahtani S, Sardar ZM, Saluja RS, Ouellet J, Weber M, Steffen T, Beckman L, Jarzem P (2015) Does balloon kyphoplasty deliver more cement safely into osteoporotic vertebrae with compression fractures compared with vertebroplasty? A study in vertebral analogues. Glob Spine J 5(4):300–307. doi:10.1055/s-0035-1546818
Kim YY, Rhyu KW (2010) Recompression of vertebral body after balloon kyphoplasty for osteoporotic vertebral compression fracture. Eur Spine J 19(11):1907–1912. doi:10.1007/s00586-010-1479-6
Ha KY, Kim KW, Kim YH, Oh IS, Park SW (2010) Revision surgery after vertebroplasty or kyphoplasty. Clin Orthop Surg 2(4):203–208. doi:10.4055/cios.2010.2.4.203
Kruger A, Oberkircher L, Kratz M, Baroud G, Becker S, Ruchholtz S (2012) Cement interdigitation and bone-cement interface after augmenting fractured vertebrae: a cadaveric study. Int J Spine Surg 6:115–123. doi:10.1016/j.ijsp.2012.02.005
Pesenti S, Blondel B, Peltier E, Adetchessi T, Dufour H, Fuentes S (2014) Percutaneous cement-augmented screws fixation in the fractures of the aging spine: is it the solution? BioMed Res Int 2014:610675. doi:10.1155/2014/610675
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Funding
This research was supported by the Jiangsu Provincial Special Program of Medical Science (BL2012004) and Clinical Research Foundation of Affiliated Hospital of Jiangsu University (JDFYRC-2013018). The funder had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Conflict of interest
The authors declare that they have no conflict of interest.
Ethical approval
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required.
Additional information
Dapeng Li and Yan Wu contributed equally to this work.
Rights and permissions
About this article
Cite this article
Li, D., Wu, Y., Huang, Y. et al. Risk factors of recompression of cemented vertebrae after kyphoplasty for osteoporotic vertebral compression fractures. International Orthopaedics (SICOT) 40, 1285–1290 (2016). https://doi.org/10.1007/s00264-016-3203-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00264-016-3203-6