Abstract
Purpose
While a majority of total hip arthroplasty (THA) is performed for osteoarthritis (OA), a significant portion is performed in the setting of avascular necrosis (AVN). The purpose of this study is to evaluate recent trends, patient demographics, and in hospital outcomes for primary THA in the setting of AVN in the United States.
Methods
The National Hospital Discharge Survey database was searched for patients admitted to US hospitals after a primary THA for the years 2001-2010. Patients were then separated into two groups by ICD-9 diagnosis codes for OA and AVN.
Results
The rates of THA for AVN (r = 0.65) and THA for OA (r = 0.82) both demonstrated a positive correlation with time. The mean patient age of the AVN group was significantly lower (56.9 vs 65.9 years, p < 0.01). Men accounted for 51.9 % of the AVN group and 43.0 % of the OA group (p < 0.01). The AVN group had a significantly higher percentage of African Americans (11.2 % vs 5.4 %, p < 0.01) when compared to the OA group. The AVN group had a higher rate of myocardial infarction (0.3 % vs 0.07 %, p = 0.0163) and a higher average number of medical co-morbidities (5.16 vs 4.77, p < 0.01).
Conclusions
Patients undergoing THA for AVN were more likely to be younger, male, African American, have more medical co-morbidities, and more likely to have a myocardial infarction than those with OA. While the number of primary THAs performed for AVN in the United States has increased over the past ten years, the rate of primary THA for OA increased at a much more rapid rate.
Similar content being viewed by others
References
Kaushik AP, Das A, Cui Q (2012) Osteonecrosis of the femoral head: an update in year 2012. World J Orthop 3(5):49–57. doi:10.5312/wjo.v3.i5.49
Issa K, Pivec R, Kapadia BH, Banerjee S, Mont M (2013) Osteonecrosis of the femoral head: the total hip replacement solution. Bone Joint J 95-B(11 Suppl A):46–50. doi:10.1302/0301-620X.95B11.32644
Johnson AJ, Mont MA, Tsao AK, Jones LC (2014) Treatment of femoral head osteonecrosis in the United States: 16-year analysis of the Nationwide Inpatient Sample. Clin Orthop Relat Res 472(2):617–623. doi:10.1007/s11999-013-3220-3
Johannson HR, Zywiel MG, Marker DR, Jones LC, McGrath MS, Mont MA (2011) Osteonecrosis is not a predictor of poor outcomes in primary total hip arthroplasty: a systematic literature review. Int Orthop 35(4):465–473. doi:10.1007/s00264-010-0979-7
Myers TG, Mihalko WM, Brown TE, Saleh KJ, Cui Q (2010) Outcomes of total hip arthroplasty for osteonecrosis of the hip: systematic review and meta-analysis. Curr Orthop Pract 21(1):81–88. doi:10.1097/BCO.0b013e3181b9b227
Jeong G (2005) Total hip arthroplasty in sickle cell hemoglobinopathies. J Am Acad Orthop Surg 13(3):208–217
Urquhart DM, Hanna FS, Brennan SL et al (2010) Incidence and risk factors for deep surgical site infection after primary total hip arthroplasty: a systematic review. J Arthroplasty 25(8):1216–22.e1-3. doi:10.1016/j.arth.2009.08.011
Hernigou P, Zilber S, Filippini P, Mathieu G, Poignard A, Galacteros F (2008) Total THA in adult osteonecrosis related to sickle cell disease. Clin Orthop Relat Res 466(2):300–308. doi:10.1007/s11999-007-0069-3
Hickman M (1997) Results and complications of total hip arthroplasties in patients with sickle-cell hemoglobinopathies role of cementless components. J Arthroplast 12(4):420–425
Soohoo NF, Farng E, Lieberman JR, Chambers L, Zingmond DS (2010) Factors that predict short-term complication rates after total hip arthroplasty. Clin Orthop Relat Res 468(9):2363–2371. doi:10.1007/s11999-010-1354-0
Phillips C, Barrett J, Losina E (2003) Incidence rates of dislocation, pulmonary embolism, and deep infection during the first six months after elective total hip replacement. J Bone Jt Surg Am 85-A(1):20–26
Ortiguera CJ, Pulliam IT, Cabanela ME (1999) Total hip arthroplasty for osteonecrosis: matched-pair analysis of 188 hips with long-term follow-up. J Arthroplasty 14:21–28. doi:10.1016/S0883-5403(99)90197-3
NHDS - National Hospital Discharge Survey Homepage. http://www.cdc.gov/nchs/nhds/about_nhds.htm
Nho SJ, Kymes SM, Callaghan JJ, Felson DT (2013) The burden of hip osteoarthritis in the United States: epidemiologic and economic considerations. J Am Acad Orthop Surg 21(Suppl 1):S1–S6. doi:10.5435/JAAOS-21-07-S1
Fukushima W, Fujioka M, Kubo T, Tamakoshi A, Nagai M, Hirota Y (2010) Nationwide epidemiologic survey of idiopathic osteonecrosis of the femoral head. Clin Orthop Relat Res 468(10):2715–2724. doi:10.1007/s11999-010-1292-x
Stavrakis A, SooHoo N, Lieberman J (2014) Comparison of the incidence of complications following total hip arthroplasty in patients with or without osteonecrosis. J Arthroplasty. doi:10.1016/j.arth.2014.08.010
Kang J-H, Lin H-C (2010) Increased risk for coronary heart disease after avascular necrosis of femoral head: a 3-year follow-up study. Am Heart J 159(5):803-808.e1. doi:10.1016/j.ahj.2010.02.020
Varas-Lorenzo C, Rodriguez LAG, Maguire A, Castellsague J, Perez-Gutthann S (2007) Use of oral corticosteroids and the risk of acute myocardial infarction. Atherosclerosis 192(2):376–383. doi:10.1016/j.atherosclerosis.2006.05.019
Pannu R, Zhang J, Andraws R, Armani A, Patel P, Mancusi-Ungaro P (2008) Acute myocardial infarction in sickle cell disease: a systematic review. Crit Pathw Cardiol 7(2):133–138. doi:10.1097/HPC.0b013e3181668ac3
Illingworth KD, El Bitar YF, Banerjee D, Scaife SL, Saleh K (2014) Inpatient mortality after primary total hip arthroplasty: analysis from the national inpatient sample database. J Arthroplasty. doi:10.1016/j.arth.2014.08.002
Olthof M, Stevens M, Bulstra SK, van den Akker-Scheek I (2014) The association between comorbidity and length of hospital stay and costs in total hip arthroplasty patients: a systematic review. J Arthroplasty 29(5):1009–1014. doi:10.1016/j.arth.2013.10.008
Belmont PJ, Goodman GP, Hamilton W, Waterman BR, Bader JO, Schoenfeld AJ (2014) Morbidity and mortality in the thirty-day period following total hip arthroplasty: risk factors and incidence. J Arthroplasty 29:2025-2030. doi:10.1016/j.arth.2014.05.015.
Styron JF, Koroukian SM, Klika AK, Barsoum WK (2011) Patient vs provider characteristics impacting hospital lengths of stay after total knee or hip arthroplasty. J Arthroplasty 26(8):1418–26.e1-2. doi:10.1016/j.arth.2010.11.008
Doro C, Dimick J, Wainess R, Upchurch G, Urquhart A (2006) Hospital volume and inpatient mortality outcomes of total hip arthroplasty in the United States. J Arthroplasty 21(6 Suppl 2):10–16. doi:10.1016/j.arth.2006.05.009
Brousseau DC, Panepinto JA, Nimmer M, Hoffmann RG (2010) The number of people with sickle-cell disease in the United States: national and state estimates. Am J Hematol 85(1):77–78. doi:10.1002/ajh.21570
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Funding
No external funding was provided for this study.
Conflict of interest
WG serves as a voluntary member of the editorial board for Journal of Arthroplasty. RS receives book royalties from Lippincott-Wolters Kluwer, serves as a consultant to Smith + Nephew, and conducts research supported by MicroPort and Zimmer Biomet.
Statement for human rights
For this type of study formal consent is not required.
Rights and permissions
About this article
Cite this article
Mayers, W., Schwartz, B., Schwartz, A. et al. National trends and in hospital outcomes for total hip arthroplasty in avascular necrosis in the United States. International Orthopaedics (SICOT) 40, 1787–1792 (2016). https://doi.org/10.1007/s00264-015-3089-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00264-015-3089-8