Skip to main content
Log in

Arthroplasty versus arthrodesis for end-stage ankle arthritis: decision analysis using Markov model

  • Original Paper
  • Published:
International Orthopaedics Aims and scope Submit manuscript

Abstract

Background

Total ankle arthroplasty and arthrodesis are the two mainstreams of treatment for end-stage ankle arthritis. This study was performed to determine which is a better choice for ankle arthritis, using a decision analysis and Markov model to reflect the repetitive nature of revision arthroplasty.

Methods

Based on current published evidence, a decision tree was constructed to compare the clinical outcomes of total ankle arthroplasty and arthrodesis, which contained the possible clinical events and the probabilities. Total ankle arthroplasty was subject to revision arthroplasty, and a Markov model was adopted for this branch to reflect this repetitive trait of the procedure. Arthrodesis could cause adjacent arthritis, and a conventional decision analysis model was adopted for this branch. Quality well-being index score was used for clinical outcome assessment, which was the utility in the decision tree. Sensitivity analysis was performed to test the stability of the decision tree and the threshold values.

Results

The model favoured total ankle arthroplasty over arthrodesis in terms of quality well-being index score. Sensitivity analysis showed that the model was considerably stable, unaffected by the changes in probabilities of failure after total ankle arthroplasty and adjacent arthritis after arthrodesis.

Conclusions

Based on current evidence, total ankle arthroplasty was found to be a better treatment than arthrodesis for ankle arthritis. Future development in the implant materials, improved understanding of ankle biomechanics, and surgical techniques will further enhance the clinical outcome of total ankle arthroplasty.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Coester LM, Saltzman CL, Leupold J, Pontarelli W (2001) Long-term results following ankle arthrodesis for post-traumatic arthritis. J Bone Joint Surg Am 83-A(2):219–228

    PubMed  CAS  Google Scholar 

  2. Bernstein J (1997) Decision analysis. J Bone Joint Surg Am 79(9):1404–1414

    PubMed  CAS  Google Scholar 

  3. SooHoo NF, Kominski G (2004) Cost-effectiveness analysis of total ankle arthroplasty. J Bone Joint Surg Am 86-A(11):2446–2455

    PubMed  Google Scholar 

  4. Hunink MG GP, Siegel JE, Weeks JC et al. (2001) Decision making in health and medicine: integrating evidence and values. Cambridge University Press

  5. Anderson T, Montgomery F, Carlsson A (2003) Uncemented STAR total ankle prostheses. Three to eight-year follow-up of fifty-one consecutive ankles. J Bone Joint Surg Am 85-A(7):1321–1329

    PubMed  Google Scholar 

  6. Bonnin M, Judet T, Colombier JA et al (2004) Midterm results of the Salto total ankle prosthesis. Clin Orthop Relat Res 424:6–18

    Article  PubMed  Google Scholar 

  7. Buechel FF Sr, Buechel FF Jr, Pappas MJ (2004) Twenty-year evaluation of cementless mobile-bearing total ankle replacements. Clin Orthop Relat Res 424:19–26

    Article  PubMed  Google Scholar 

  8. Knecht SI, Estin M, Callaghan JJ et al (2004) The Agility total ankle arthroplasty. Seven to sixteen-year follow-up. J Bone Joint Surg Am 86-A(6):1161–1171

    PubMed  Google Scholar 

  9. Hurowitz EJ, Gould JS, Fleisig GS, Fowler R (2007) Outcome analysis of agility total ankle replacement with prior adjunctive procedures: two to six year followup. Foot Ankle Int 28(3):308–312

    Article  PubMed  Google Scholar 

  10. Kopp FJ, Patel MM, Deland JT, O'Malley MJ (2006) Total ankle arthroplasty with the Agility prosthesis: clinical and radiographic evaluation. Foot Ankle Int 27(2):97–103

    PubMed  Google Scholar 

  11. San Giovanni TP, Keblish DJ, Thomas WH, Wilson MG (2006) Eight-year results of a minimally constrained total ankle arthroplasty. Foot Ankle Int 27(6):418–426

    PubMed  Google Scholar 

  12. Naal FD, Impellizzeri FM, Loibl M et al (2009) Habitual physical activity and sports participation after total ankle arthroplasty. Am J Sports Med 37(1):95–102

    Article  PubMed  Google Scholar 

  13. Valderrabano V, Pagenstert G, Horisberger M et al (2006) Sports and recreation activity of ankle arthritis patients before and after total ankle replacement. Am J Sports Med 34(6):993–999

    Article  PubMed  Google Scholar 

  14. Kofoed H (2004) Scandinavian total ankle replacement (STAR). Clin Orthop Relat Res 424:73–79

    Article  PubMed  Google Scholar 

  15. Wood PL, Prem H, Sutton C (2008) Total ankle replacement: medium-term results in 200 Scandinavian total ankle replacements. J Bone Joint Surg Br 90(5):605–609

    Article  PubMed  CAS  Google Scholar 

  16. Takakura Y, Tanaka Y, Kumai T et al (2004) Ankle arthroplasty using three generations of metal and ceramic prostheses. Clin Orthop Relat Res 424:130–136

    Article  PubMed  Google Scholar 

  17. Haddad SL, Coetzee JC, Estok R et al (2007) Intermediate and long-term outcomes of total ankle arthroplasty and ankle arthrodesis. A systematic review of the literature. J Bone Joint Surg Am 89(9):1899–1905

    Article  PubMed  CAS  Google Scholar 

  18. Gougoulias N, Khanna A, Maffulli N (2010) How successful are current ankle replacements?: a systematic review of the literature. Clin Orthop Relat Res 468(1):199–208

    Article  PubMed  Google Scholar 

  19. Pyevich MT, Saltzman CL, Callaghan JJ, Alvine FG (1998) Total ankle arthroplasty: a unique design. Two to twelve-year follow-up. J Bone Joint Surg Am 80(10):1410–1420

    PubMed  CAS  Google Scholar 

  20. Tallon C, Coleman BD, Khan KM, Maffulli N (2001) Outcome of surgery for chronic Achilles tendinopathy. A critical review. Am J Sports Med 29(3):315–320

    PubMed  CAS  Google Scholar 

  21. Glazebrook MA, Arsenault K, Dunbar M (2009) Evidence-based classification of complications in total ankle arthroplasty. Foot Ankle Int 30(10):945–949

    Article  PubMed  Google Scholar 

  22. Thomas RH, Daniels TR (2003) Ankle arthritis. J Bone Joint Surg Am 85-A(5):923–936

    PubMed  Google Scholar 

  23. Mazur JM, Schwartz E, Simon SR (1979) Ankle arthrodesis. Long-term follow-up with gait analysis. J Bone Joint Surg Am 61(7):964–975

    PubMed  CAS  Google Scholar 

  24. Jackson A, Glasgow M (1979) Tarsal hypermobility after ankle fusion—fact or fiction? J Bone Joint Surg Br 61-B(4):470–473

    PubMed  CAS  Google Scholar 

  25. Ahlberg A, Henricson AS (1981) Late results of ankle fusion. Acta Orthop Scand 52(1):103–105

    Article  PubMed  CAS  Google Scholar 

  26. Fryback DG, Dasbach EJ, Klein R et al (1993) The Beaver Dam Health Outcomes Study: initial catalog of health-state quality factors. Med Decis Making 13(2):89–102

    Article  PubMed  CAS  Google Scholar 

  27. Coons SJ, Rao S, Keininger DL, Hays RD (2000) A comparative review of generic quality-of-life instruments. PharmacoEconomics 17(1):13–35

    Article  PubMed  CAS  Google Scholar 

  28. Centers for Medicare and Medicaid Services (2005) Physician fee schedule relative value file. CMMS, Baltimore, Maryland. www.cms.hhs.gov. Accessed 18 May 2009

  29. Centers for Medicare and Medicaid Services (2004) Revisions to payment policies under the physician fee schedule for calendar year. CMMS, Baltimore, Maryland. www.cms.hhs.gov. Accessed 18 May 2009

  30. Tengs TO, Wallace A (2000) One thousand health-related quality-of-life estimates. Med Care 38(6):583–637

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgment

The authors wish to thank Mi Sun Ryu, BS for data collection.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kyoung Min Lee.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kwon, D.G., Chung, C.Y., Park, M.S. et al. Arthroplasty versus arthrodesis for end-stage ankle arthritis: decision analysis using Markov model. International Orthopaedics (SICOT) 35, 1647–1653 (2011). https://doi.org/10.1007/s00264-011-1336-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00264-011-1336-1

Keywords

Navigation