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Society of abdominal radiology survey of practice patterns in using LI-RADS treatment response criteria in the evaluation of hepatocellular carcinoma post-locoregional treatment

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Abstract

Purpose

To examine national trends in the adoption and use of the LI-RADS Treatment Response Algorithm.

Methods

Members of the Society of Abdominal Radiology (SAR) Disease-Focused Panel (DFP) on LI-RADS Treatment Response (LR-TR) of hepatocellular carcinoma (HCC) developed a 15-question survey which was distributed to radiologists at academic and private practice institutions around the USA and Canada. The survey focused on HCC-related practice patterns as well as the adoption and use of the LR-TR algorithm.

Results

Of 122 surveys distributed, a total of 76 radiologists responded (62%). Responders were predominantly from academic centers (85%). Nearly all (96%) participate in multidisciplinary hepatic tumor boards and most (67%) have an active liver transplant program. All responders’ institutions perform locoregional therapy for HCC, including radiation-based therapy (TARE and SBRT). There was a preference for use of MRI over CT for follow-up after locoregional therapy. All responders were aware of the LR-TR algorithm and nearly all (92%) used the system in routine practice. Radiologists expressed a need for more visual aids related to the LR-TR system. Multiple respondents requested additional clarity within the LR-TR algorithm regarding the evolution of post-treatment radiation changes over time.

Conclusion

Most survey participants use the LR-TR algorithm after locoregional therapy for HCC. Future iterations of the algorithm may benefit from increased clarity regarding response after radiation-based therapies. Educational materials should include more visual aids to improve reader understanding.

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Acknowledgements

The authors would like to thank Markeela Lipscomb, clinical research coordinator, without whom this survey would not have been possible.

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Authors and Affiliations

  1. Department of Radiological Sciences, University of California Irvine, 101 The City Drive South, Orange, CA, 92868, USA

    Rony Kampalath & Vahid Yaghmai

  2. Radiology, University of Michigan School of Medicine, 1500 East Medical Center Drive, UH B2A209R, Ann Arbor, MI, 48109-5030, USA

    Mishal Mendiratta-Lala

  3. Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1234, New York, NY, 10029-6574, USA

    Sara Lewis

  4. Carolina Mammography Registry, University of North Carolina at Chapel Hill, CB #7510, Bioinformatics Building Room 3125, Chapel Hill, NC, 27599-7515, USA

    Thad Benefield

  5. Department of Radiology, University of North Carolina at Chapel Hill School of Medicine, 2000 Old Clinic, CB# 7510, Chapel Hill, NC, 27599, USA

    Lauren Burke

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  1. Rony Kampalath
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  2. Mishal Mendiratta-Lala
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Correspondence to Rony Kampalath.

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Kampalath, R., Mendiratta-Lala, M., Lewis, S. et al. Society of abdominal radiology survey of practice patterns in using LI-RADS treatment response criteria in the evaluation of hepatocellular carcinoma post-locoregional treatment. Abdom Radiol 48, 3401–3407 (2023). https://doi.org/10.1007/s00261-023-04022-9

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  • DOI: https://doi.org/10.1007/s00261-023-04022-9

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