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Comparison of the magnetic resonance scoring systems for Crohn’s disease activity: MaRIA, simplified MaRIA, and Nancy scores

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Abstract

Purpose

The most widely used score for assessing the activity of Crohn’s disease (CD) is the Magnetic Resonance Index of Activity (MaRIA) score, but it is time-consuming. The aim of this study was to compare the diagnostic accuracy of MaRIA score to the other two easily calculated scores.

Methods

Between January 2011 and May 2021, 67 patients with CD who underwent MRE and ileocolonoscopy within 2 weeks were enrolled. The MRE-based scores including the MaRIA score, simplified MaRIA (sMaRIA) score, and Nancy score for each colonic segment and terminal ileum were calculated and correlated with the ileocolonoscopic findings. The simplified endoscopic score for Crohn's disease (SES-CD) was considered the gold standard.

Results

A total of 343 intestinal segments were included in the analysis, of which 109 (31.8%) showed active inflammation on ileocolonoscopy. The areas under the receiver operating characteristic curve (AUC) of the MaRIA, sMaRIA, and Nancy scores for detecting active disease were 0.752, 0.764, and 0.765, respectively. In the sub-analysis for different indications, the MaRIA and sMaRIA scores showed a higher AUC (0.721 and 0.741) than the Nancy score (0.652) for disease monitoring.

Conclusion

The sMARIA and Nancy scores showed comparable diagnostic accuracy to the MaRIA score, and thus could be used as alternatives to the MaRIA score. Furthermore, considering the range of application, especially for disease monitoring, the sMaRIA score may be more suitable for use in clinical practice.

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Data availability

The datasets generated or analyzed during the study are available from the corresponding author on reasonable request.

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Funding

The authors did not receive support from any organization for the submitted work.

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Authors and Affiliations

  1. Department of Medical Imaging, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, 100, Taiwan

    Wei-En Lee & I-Lun Shih

  2. Department of Radiology, College of Medicine, National Taiwan University, Taipei, Taiwan

    Wei-En Lee & I-Lun Shih

  3. Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

    Meng-Tzu Weng & Shu-Chen Wei

  4. Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan

    Meng-Tzu Weng & Shu-Chen Wei

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  1. Wei-En Lee
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  2. Meng-Tzu Weng
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  4. I-Lun Shih
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Contributions

SCW, ILS: Conceptualization, WEL, ILS, MTW: Data curation, WEL: Formal analysis, WEL, ILS: Investigation, ILS: Methodology, ILS: Project administration, SCW, ILS: Resources and Supervision, ILS: Validation, WEL, ILS: Visualization, WEL: Writing—original draft, WEL, ILS, MTW, SCW: Writing—review & editing.

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Correspondence to I-Lun Shih.

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Competing interests

The authors have no competing interests to declare that are relevant to the content of this article.

Ethical approval

Approval was obtained from the ethics committee of National Taiwan University Hospital. The procedures used in this study adhere to the tenets of the Declaration of Helsinki.

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Informed consent was waived by the local Ethics Committee of National Taiwan University Hospital in view of the retrospective nature of the study.

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There is no identifying information in the images of the study, therefore it is not necessary to obtain consent.

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Lee, WE., Weng, MT., Wei, SC. et al. Comparison of the magnetic resonance scoring systems for Crohn’s disease activity: MaRIA, simplified MaRIA, and Nancy scores. Abdom Radiol 48, 2228–2236 (2023). https://doi.org/10.1007/s00261-023-03926-w

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  • DOI: https://doi.org/10.1007/s00261-023-03926-w

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