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Magnetic resonance imaging findings of pure prostatic ductal adenocarcinomas: a case series

  • Special Section: Male pelvis
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Abdominal Radiology Aims and scope Submit manuscript

Abstract

Purpose

This study aimed to investigate the characteristics of magnetic resonance imaging (MRI) findings in pure prostatic ductal adenocarcinoma.

Methods

From January 2009 to February 2020, seven patients who were diagnosed with pure prostatic ductal adenocarcinoma and had a referable preoperative MRI scan were included in the study. We evaluated the following MRI findings for each tumor: size, location, presence of multi-cystic component, and apparent diffusion coefficient (ADC) value.

Results

The median maximum diameter of the tumors was 22 mm (range 19–70 mm). Regarding transverse distribution, five tumors were located in the periurethral area and two were located peripherally apart from the urethra. Two of the seven tumors had cystic components. The median ADC value of the tumors was 0.754 × 10–3 mm2/s (range 0.570–0.963 × 10–3 mm2/s). Based on the transverse distribution and components of the tumors on MRI, ductal adenocarcinomas were classified into three types: type I as a non-cystic tumor located peripherally apart from the urethra (29%, two cases); type II as a non-cystic tumor located in the periurethral area (43%, three cases); and type III as a tumor with a multi-cystic component (29%, two cases).

Conclusion

The non-cystic mass with periurethral distribution (type II) and multi-cystic mass (type III) may be characteristic features that differentiate pure ductal adenocarcinoma from ordinary acinar adenocarcinoma on MRI.

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Acknowledgements

We would like to thank Editage (www.editage.jp) for English language editing.

Funding

No funding was received to assist with the preparation of this manuscript.

Author information

Authors and Affiliations

  1. Department of Radiology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan

    Hiromi Edo & Hiroshi Shinmoto

  2. Department of Radiology, Kobe University Graduate School of Medicine, 7-5-1 Kusunokicho, Kobe Chuo-ku, Hyogo, 650-0017, Japan

    Yasuyo Urase & Yoshiko Ueno

  3. Department of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701-0192, Japan

    Ayumu Kido & Tsutomu Tamada

  4. Department of Radiology, Fukuyama City Hospital, 5-23-1 Zaocho, Fukuyama, Hiroshima, 721-8511, Japan

    Yudai Asano & Kentaro Ida

  5. Department of Radiology, Osaka Red Cross Hospital, 5-30 Fudegasakicho, Tennoji-ku, Osaka, 543-8555, Japan

    Hisataka Ito

  6. Department of Diagnostic Radiology, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki, Okayama, 710-8602, Japan

    Takashi Koyama

  7. Department of Pathology, Japan Self-Defense Forces Central Hospital, 1-2-24 Ikejiri, Setagaya-ku, Tokyo, 154-8532, Japan

    Kosuke Miyai

  8. Department of Basic Pathology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan

    Hitoshi Tsuda

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  1. Hiromi Edo
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Contributions

HE and HS were involved in the study design, acquisition of data, analysis and interpretation of data, and drafting of the manuscript. YU, YU, AK, TT, YA, KI, HI, and TK were involved in the data collection and drafting of the manuscript. KM and HT were involved in the analysis and interpretation of data and drafting the manuscript. All authors reviewed and approved the final manuscript.

Corresponding author

Correspondence to Hiroshi Shinmoto.

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Conflict of interest

The authors have no relevant financial or non-financial interests to disclose.

Ethical approval

This study complied with the ethical guidelines of the Declaration of Helsinki and was approved by our institutions’ ethics committees (National Defense Medical College: 4457; Kobe University Graduate School of Medicine: B210228; Kawasaki Medical School: 5498-00; Fukuyama City Hospital: 627; and Kurashiki Central Hospital: 3756). Written informed consent for participation was waived owing to the retrospective nature of the study, and patient records were anonymously analyzed.

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Edo, H., Urase, Y., Ueno, Y. et al. Magnetic resonance imaging findings of pure prostatic ductal adenocarcinomas: a case series. Abdom Radiol 47, 1929–1938 (2022). https://doi.org/10.1007/s00261-022-03454-z

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  • DOI: https://doi.org/10.1007/s00261-022-03454-z

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