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Imaging considerations for thermal and radiotherapy ablation of primary and metastatic renal cell carcinoma

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Abstract

Ablative (percutaneous and stereotactic) thermal and radiotherapy procedures for management of both primary and metastatic renal cell carcinoma are increasing in popularity in clinical practice. Data suggest comparable efficacy with lower cost and morbidity compared to nephrectomy. Ablative therapies may be used alone or in conjunction with surgery or chemotherapy for treatment of primary tumor and metastatic disease. Imaging plays a crucial role in pre-treatment selection and planning of ablation, intra-procedural guidance, evaluation for complications, short- and long-term post-procedural surveillance of disease, and treatment response. Treatment response and disease recurrence may differ considerably after ablation, particularly for stereotactic radiotherapy, when compared to conventional surgical and chemotherapies. This article reviews the current and emerging role of imaging for ablative therapy of renal cell carcinoma.

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  1. Department of Medical Imaging, The Ottawa Hospital, University of Ottawa, 501 Smyth Road, Ottawa, ON, K1B 4L9, Canada

    Mohammad Haroon, Paul Sathiadoss, Rebecca M. Hibbert & Nicola Schieda

  2. Joint Department of Medical Imaging, University of Toronto, 585 University Avenue, Toronto, ON, M5G 2N2, Canada

    Satheesh Krishna Jeyaraj

  3. Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada

    Christopher Lim

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Haroon, M., Sathiadoss, P., Hibbert, R.M. et al. Imaging considerations for thermal and radiotherapy ablation of primary and metastatic renal cell carcinoma. Abdom Radiol 46, 5386–5407 (2021). https://doi.org/10.1007/s00261-021-03178-6

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