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Diagnosis of hilar cholangiocarcinoma using intravoxel incoherent motion diffusion-weighted magnetic resonance imaging

  • Interventional Radiology
  • Published:
Abdominal Radiology Aims and scope Submit manuscript

Abstract

Objective

To investigate the value of intravoxel incoherent motion diffusion-weighed magnetic resonance imaging (IVIM-DWI) in discriminating the pathological grades of hilar cholangiocarcinoma (HC).

Patients and methods

Thirty-seven HC patients were enrolled and received routine and advanced DWI scanning with multiple b-values. IVIM-DWI images were obtained using echo-planar imaging sequence.

Results

The consistency of the maximum cross-sectional area ROI measuring method was higher than that of the repeated sampling ROI measuring method. ADCslow values were closely correlated with the pathological grades of HC. The degrees of biliary dilatation and MELD scores had no influence on the negative correlation between ADCslow values and the pathological degrees of HC patients.

Conclusions

ADCslow values could be applied in indicating the pathological grades of HC, which was independent on the extent of biliary dilatation.

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Authors and Affiliations

  1. Department of Radiology, Tianjin Nankai Hospital, Nankai District, No. 6 Chang Jiang Road, Tianjin, 300100, China

    Xin Xu

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  1. Xin Xu
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Correspondence to Xin Xu.

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The authors declare that there is no conflict of interest.

Ethical approval

The study was approved by the Ethics Committee of the Institution of Tianjin Hospital of ITCWM, Nankai Hospital, and was conducted in accordance with the 1975 Declaration of Helsinki.

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Cite this article

Xu, X. Diagnosis of hilar cholangiocarcinoma using intravoxel incoherent motion diffusion-weighted magnetic resonance imaging. Abdom Radiol 46, 3159–3167 (2021). https://doi.org/10.1007/s00261-021-02997-x

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  • DOI: https://doi.org/10.1007/s00261-021-02997-x

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