Neuroblastic tumors in young adults as a sequela of malignant neuroblastoma: report of two cases

  • Takuya Adachi
  • Minato Yokoyama
  • Yasuhisa Fujii
  • Yuko Kinowaki
  • Susumu Kirimura
  • Kazunori Kubota
  • Yukihisa Saida
  • Ukihide Tateishi
JSAR Submission

Abstract

Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma share the same histological spectrum which originates from neural crest cells. We present herein two young adult patients with neuroblastic tumors with lymph node metastases. Both the patients were diagnosed incidentally as having retroperitoneal masses, which showed little or no immature cells despite coexistence of lymph node involvement. The tumors were considered to represent spontaneous regression of malignant neuroblastoma. Radiologists should consider the possibility of spontaneous regression of neuroblastic tumors, when poorly enhanced multi-component masses at the retroperitoneum with lymph node involvement are visualized.

Keywords

Neuroblastoma Ganglioneuroblastoma Ganglioneuroma Neuroblastic tumors Spontaneous regression 

Notes

Compliance with ethical standards

Funding

This study received no specific grant from any funding agency.

Conflict of interest

The authors declare no conflicts of interest associated with this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Diagnostic RadiologyTokyo Medical and Dental UniversityTokyoJapan
  2. 2.Department of UrologyTokyo Medical and Dental UniversityTokyoJapan
  3. 3.Department of Comprehensive PathologyTokyo Medical and Dental UniversityTokyoJapan

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