Abdominal Radiology

, Volume 43, Issue 1, pp 26–40 | Cite as

Cirrhosis and LI-RADS

  • Demetrios Papadatos
  • Kathryn J. Fowler
  • Ania Z. Kielar
  • Jennifer Cui
  • Claude B. Sirlin
Invited article


Chronic liver disease, irrespective of cause, can eventually lead to cirrhosis, which is the primary risk factor for developing hepatocellular carcinoma (HCC). In patients with cirrhosis or appropriate risk factors, HCC can be diagnosed by imaging with high specificity using liver imaging reporting and data system v2017, obviating the need for histologic confirmation. Confident recognition of cirrhosis by conventional imaging alone can be challenging, as radiologists are not always provided with the requisite information to determine if the patient has cirrhosis or other risk factors for HCC. Moreover, cirrhosis-associated abnormalities may impair the diagnostic accuracy of imaging for HCC. This article addresses the diagnosis of cirrhosis by non-invasive imaging and the implications of cirrhosis for imaging interpretation and accuracy.


LI-RADS Cirrhosis Fibrosis Hepatocellular carcinoma Hepatocellular nodules Magnetic resonance imaging 


Compliance with ethical standards


This article has received no funding support.

Conflict of interest

Dr. Papadatos, Dr. Fowler, and Ms. Cui have no relevant conflicts of interest, Dr. Kielar reports research grants from GE, and Dr. Sirlin reports research grants from GE and Siemens.

Ethical approval

This article does not contain any studies with human participants performed by any of the authors.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2017

Authors and Affiliations

  • Demetrios Papadatos
    • 1
  • Kathryn J. Fowler
    • 2
  • Ania Z. Kielar
    • 1
  • Jennifer Cui
    • 3
  • Claude B. Sirlin
    • 3
  1. 1.University of OttawaOttawaCanada
  2. 2.Department of Radiology, Washington University School of MedicineWashington UniversitySt. LouisUSA
  3. 3.University of California, San DiegoSan DiegoUSA

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