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Abdominal Radiology

, Volume 42, Issue 11, pp 2745–2751 | Cite as

Unilateral versus bilateral stent insertion for malignant hilar biliary obstruction

  • Gang Chang
  • Feng-Fei Xia
  • Hong-Fu Li
  • Su Niu
  • Yuan-Shun XuEmail author
Article

Abstract

Purpose

To determine the clinical efficiency and long-term outcomes between unilateral and bilateral stent insertion in patients with malignant hilar biliary obstruction.

Methods

From August 2012 to February 2016, 63 consecutive patients with malignant hilar biliary obstruction were treated with unilateral or bilateral stent insertion at our center. The bilateral stents were inserted using the side-by-side technique. The clinical efficiency and long-term outcomes were compared between the two groups.

Results

Unilateral and bilateral stent insertions were successfully performed in 31 of 33 and 27 of 30 patients, respectively (P = 0.912). No procedure-related complication occurred. Clinical success was achieved in 29 of 31 patients in the unilateral stent group and in 26 of 27 patients in the bilateral stent group (P = 0.637). During the follow-up, re-obstruction of stent occurred in five patients in the unilateral stent group and in three patients in the bilateral stent group (P = 0.58). The significant differences were not observed in the stent patency time (368 vs. 387 days, P = 0.685) and survival (200 vs. 198 days, P = 0.751) between two groups. Based on the univariate and multivariate analyses, the independent risk factors for decreasing the survival time included higher Eastern Cooperative Oncology Group performance status (P = 0.018), higher alanine aminotransferase level (P = 0.009), and absence of anticancer treatment after stent insertion (P = 0.002).

Conclusion

Compared to bilateral stent insertion for malignant hilar biliary obstruction, unilateral stent insertion can provide comparable clinical efficiency and long-term outcomes.

Keywords

Unilateral stent insertion Bilateral stent insertion Hilar biliary obstruction 

Notes

Compliance with ethical standards

Funding

No funding was received for this study.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required. This article does not contain any studies with animals performed by any of the authors.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Gang Chang
    • 1
  • Feng-Fei Xia
    • 1
  • Hong-Fu Li
    • 1
  • Su Niu
    • 2
  • Yuan-Shun Xu
    • 3
    Email author
  1. 1.Department of Interventional Vascular SurgeryBinzhou People’s HospitalBinzhouChina
  2. 2.Department of Interventional RadiologyXuzhou Central HospitalXuzhouChina
  3. 3.Department of RadiologyXuzhou Central HospitalXuzhouChina

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