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CT sensitivities for large (≥3 cm) adrenal adenoma and cortical carcinoma

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Abstract

Purpose

To retrospectively compare computed tomography (CT) sensitivities of large (≥3 cm) adenoma and cortical carcinoma.

Methods

Between January 2004 and November 2012, 43 non-oncologic patients with 43 adrenal masses [31 large adenomas, and 12 carcinomas] underwent unenhanced CT, early contrast-enhanced CT, and delayed contrast-enhanced CT scans prior to adrenalectomy. Three types of region-of-interest (ROI) were used on early contrast-enhanced CT images:aROI (large ROI) covering more than half of a mass and two small ROIs fitted to the highest (high ROI) or lowest (low ROI) attenuation area. These ROIs were also placed in the same area on the other CT images. Adenoma was diagnosed if a mass measured ≤10 HU on unenhanced CT image, or if it had ≥60% absolute percentage washout (APW)or ≥40% relative percentage washout (RPW).Carcinoma was diagnosed if a mass had <60% APW and <40% RPW. CT sensitivities for large adenoma and carcinoma were compared.

Results

CT sensitivities for large adenoma vs. carcinoma were 64.5% (20/31) vs. 100% (12/12) using a large ROI, 100% (31/31) vs. 50.0% (6/12) using a high ROI, and 51.6% (16/31) vs. 100% (12/12) using a low ROIs, respectively.

Conclusions

CT sensitivities for large adenoma and cortical carcinoma are influenced by the size or location of an ROI.A large ROI helps to minimize loss of CT sensitivity for large adenoma and to detect carcinoma.

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Conflict of interest

None of authors have conflict or interest or financial support to disclose.

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Authors and Affiliations

  1. Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, Seoul, 135-710, Korea

    Sung Yoon Park, Byung Kwan Park, Jung Jae Park & Chan Kyo Kim

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  1. Sung Yoon Park
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  2. Byung Kwan Park
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  3. Jung Jae Park
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Correspondence to Byung Kwan Park.

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Park, S.Y., Park, B.K., Park, J.J. et al. CT sensitivities for large (≥3 cm) adrenal adenoma and cortical carcinoma. Abdom Imaging 40, 310–317 (2015). https://doi.org/10.1007/s00261-014-0202-1

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  • DOI: https://doi.org/10.1007/s00261-014-0202-1

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