Abdominal Radiology

, Volume 37, Issue 5, pp 795–802 | Cite as

Early phase detection of bile leak after hepatobiliary surgery: value of Gd-EOB-DTPA-enhanced MR cholangiography

  • Alvaro Alegre CastellanosEmail author
  • Juan Felix Molina Granados
  • Jose Escribano Fernandez
  • Inmaculada Gallardo Muñoz
  • Francisco de Asis Triviño Tarradas



To assess the value of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced MR cholangiography for the detection of bile leaks after hepatobiliary surgery.


Twenty-three patients with symptoms suggestive of bile leak underwent conventional fat-suppressed T1- and T2-weighted MR cholangiography followed by Gd-EOB-DTPA-enhanced MR cholangiography using gradient-echo (GRE) T2-weighted sequences and fat-suppressed T1-weighted 3D gradient-echo sequences 20 min after an intravenous bolus of Gd-EOB-DTPA. The results of Gd-EOB-DTPA-enhanced MR cholangiography correlated with clinical findings, surgical repair, and the results of endoscopic retrograde cholangiopancreatography and percutaneous transhepatic cholangiography.


The results of Gd-EOB-DTPA-enhanced MR cholangiography were negative in 13 patients (cholecystectomy 5, liver transplantation 2, liver resection for focal lesions 2, cholangiocarcinoma 1, and partial hepatectomy after liver injury 1). In 10 patients in whom bile leaks were detected, this complication occurred after liver resection for focal lesions in 3, cholecystectomy in 4, liver transplantation in 2, and liver resection for intrahepatic cholangiocarcinoma in 1. The diagnostic accuracy of Gd-EOB-DTPA-enhanced MR for the detection or exclusion of bile leaks was 100%.


Gd-EOB-DTPA-enhanced MR cholangiography is a highly reliable technique for the detection of bile leaks after hepatobiliary surgery and may avoid the use of other, potentially risky invasive diagnostic techniques.


Gd-EOB-DTPA Cholangiography Bile ducts Postsurgical complications Bile leak 



To Content’Ed Net Communications, S.L., for editorial assistance and Marta Pulido, MD, for editing the manuscript.


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Alvaro Alegre Castellanos
    • 1
    Email author
  • Juan Felix Molina Granados
    • 2
  • Jose Escribano Fernandez
    • 1
  • Inmaculada Gallardo Muñoz
    • 1
  • Francisco de Asis Triviño Tarradas
    • 1
  1. 1.Radiodiagnosis and Imaging ServiceHospital Universitario Reina SofíaCordobaSpain
  2. 2.Unidad Central de Radiodiagnóstico de la Comunidad de MadridHospital del SuresteArganda del Rey, MadridSpain

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