Skip to main content

Advertisement

SpringerLink
Log in

Intestinal and multivisceral transplantation

  • Pictorial essay
  • Published:
Abdominal Imaging Aims and scope

Abstract

Intestinal transplantation is carried out in only a handful of centers in the world. However, patients with such transplantation may be seen at almost any institution and radiologists should be familiar with the expected normal anatomy and complications of intestinal transplantation and its variants. In this paper, we discuss the anatomy and complications following intestinal and multivisceral transplantations. We review the literature and present the findings in a cohort of 46 patients who underwent these procedures at our institution. It is important not to misinterpret the normal adaptation of the transplanted intestine for disease. Some of the complications, including infections, vascular complications, and recurrent tumor, are conclusively diagnosed on imaging studies. Imaging studies may raise the diagnosis of complications such as rejection, graft-versus-host disease, posttransplant lymphoproliferative disease, and sclerosing peritonitis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11

Similar content being viewed by others

References

  1. Abu-Elmagd K, Reyes J, Bond G, et al. (2001) Clinical intestinal transplantation: a decade of experience at a single center. Ann Surg 234(3):404–416

    Article  PubMed  CAS  Google Scholar 

  2. Chiba T, Yokosuka O, Goto S, et al. (2005) Clinicopathological features in patients with hepatic graft-versus-host disease. Hepatogastroenterology 52(66):1849–1853

    PubMed  Google Scholar 

  3. Donnelly LF, Morris CL (1996) Acute graft-versus-host disease in children: abdominal CT findings. Radiology 199(1):265–268

    PubMed  CAS  Google Scholar 

  4. Franquet T, Rodriguez S, Hernandez JM, et al. (2007) Air-leak syndromes in hematopoietic stem cell transplant recipients with chronic GVHD: high-resolution CT findings. J Thorac Imaging 22(4):335–340

    Article  PubMed  Google Scholar 

  5. Fryer JP (2008) The current status of intestinal transplantation. Curr Opin Organ Transpl 13(3):266–272

    Article  Google Scholar 

  6. Graham NJ, Muller NL, Miller RR, Shepherd JD (1991) Intrathoracic complications following allogeneic bone marrow transplantation: CT findings. Radiology 181(1):153–156

    PubMed  CAS  Google Scholar 

  7. Grant D, bu-Elmagd K, Reyes J, et al. (2005) 2003 Report of the intestine transplant registry: a new era has dawned. Ann Surg 241(4):607–613

    Article  PubMed  Google Scholar 

  8. Guaraldi G, Cocchi S, De Ruvo N, et al. (2004) Outcome, incidence, and timing of infections in small bowel/multivisceral transplantation. Transplant Proc 36(2):383–385

    Article  PubMed  CAS  Google Scholar 

  9. Howard L, Malone M (1996) Current status of home parenteral nutrition in the United States. Transplant Proc 28(5):2691–2695

    PubMed  CAS  Google Scholar 

  10. Intestinal Transplant Registry Data (2009) http://www.intestinaltransplant.org/; last accessed Dec 23, 2010

  11. Mazariegos GV, bu-Elmagd K, Jaffe R, et al. (2004) Graft versus host disease in intestinal transplantation. Am J Transplant 4(9):1459–1465

    Article  PubMed  Google Scholar 

  12. McDonald GB, Sullivan KM, Plumley TF (1984) Radiographic features of esophageal involvement in chronic graft-vs.-host disease. AJR Am J Roentgenol 142(3):501–506

    PubMed  CAS  Google Scholar 

  13. Moon JI, Selvaggi G, Nishida S, et al. (2005) Intestinal transplantation for the treatment of neoplastic disease. J Surg Oncol 92(4):284–291

    Article  PubMed  Google Scholar 

  14. Oltean M, Herlenius G, Gabel M, Friman V, Olausson M (2006) Infectious complications after multivisceral transplantation in adults. Transplant Proc 38(8):2683–2685

    Article  PubMed  CAS  Google Scholar 

  15. Pecchi A, De Santis M, Torricelli P, et al. (2005) Radiologic imaging of the transplanted bowel. Abdom Imaging 30(5):548–563

    Article  PubMed  CAS  Google Scholar 

  16. Quintini C, Kato T, Gaynor JJ, et al. (2006) Analysis of risk factors for the development of posttransplant lymphoprolipherative disorder among 119 children who received primary intestinal transplants at a single center. Transplant Proc 38(6):1755–1758

    Article  PubMed  CAS  Google Scholar 

  17. Ramos E, Molina M, Sarria J, et al. (2007) Chronic rejection with sclerosing peritonitis following pediatric intestinal transplantation. Pediatr Transplant 11(8):937–941

    Article  PubMed  Google Scholar 

  18. Ruiz P, Kato T, Tzakis A (2007) Current status of transplantation of the small intestine. Transplantation 83(1):1–6

    Article  PubMed  Google Scholar 

  19. Schmit M, Bethge W, Beck R, et al. (2008) CT of gastrointestinal complications associated with hematopoietic stem cell transplantation. AJR Am J Roentgenol 190(3):712–719

    Article  PubMed  Google Scholar 

  20. Smith DM, Agura E, Netto G, et al. (2003) Liver transplant-associated graft-versus-host disease. Transplantation 75(1):118–126

    Article  PubMed  CAS  Google Scholar 

  21. Tzakis AG, Kato T, Levi DM, et al. (2005) 100 multivisceral transplants at a single center. Ann Surg 242(4):480–490

    PubMed  Google Scholar 

  22. Tzakis AG, Kato T, Nishida S, et al. (2006) The Miami experience with almost 100 multivisceral transplants. Transplant Proc 38(6):1681–1682

    Article  PubMed  CAS  Google Scholar 

  23. Vianna RM, Mangus RS, Tector AJ (2008) Current status of small bowel and multivisceral transplantation. Adv Surg 42:129–150

    Article  PubMed  Google Scholar 

  24. Ziring D, Tran R, Edelstein S, et al. (2004) Infectious enteritis after intestinal transplantation: incidence, timing, and outcome. Transplant Proc 36(2):379–380

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Indiana University School of Medicine, Indianapolis, IN, USA

    Kumaresan Sandrasegaran, Raja Ramaswamy, Ryan Redelman & Stephan Hoff

  2. Department of Radiology, University of California, Irvine, CA, USA

    Chandana Lall

  3. Department of Radiology, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom

    Arumugam Rajesh

  4. Department of Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN, USA

    Rodrigo Vianna

Authors
  1. Kumaresan Sandrasegaran
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Chandana Lall
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Raja Ramaswamy
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Ryan Redelman
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Stephan Hoff
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Arumugam Rajesh
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Rodrigo Vianna
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kumaresan Sandrasegaran.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sandrasegaran, K., Lall, C., Ramaswamy, R. et al. Intestinal and multivisceral transplantation. Abdom Imaging 36, 382–389 (2011). https://doi.org/10.1007/s00261-010-9680-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00261-010-9680-y

Key words

Search

Navigation