Abstract
Purpose
To present unique CT imaging findings of the liver in Wilson’s disease.
Materials and methods
Thirteen consecutive subjects with clinically and/or pathologically proven Wilson’s disease underwent abdominal Computer Tomography examination.
Results
Hyperdense nodules and a honeycomb appearance were observed on unenhanced CT in 92.31 and 58.33% of our patients, respectively.
Conclusion
Wilson’s disease involving the liver has several unique CT findings in comparison to other types of cirrhosis. These specific features include hyperdense nodules and a honeycomb pattern not only in portal and parenchymal phases, but also in the pre-contrast scan.
Similar content being viewed by others
References
Erden A (1998) The prognostic value of a rare monographic pattern in Wilson’s disease. Acta Radiol 39:179
Mergo PJ, Ros PR, Buetow PC, Buck JL (1994) Diffuse disease of the liver: radiologic and pathologic correlation. Radiographics 14:1291–1307
Akhan O, Akpinar E, Oto A, et al. (2002) Unusual imaging findings in Wilson’s disease. Eur Radiol 12:66–69
Cancado EL, Rocha Mde S, Barbosa ER, et al. (1987) Abdominal ultrasonography in hepatolenticular degeneration. A study of 33 patients. Arq Neuropsiquiatr 45:131–136
Corda R, Nurchi AM, Corrias A, et al. (1987) Importance and significance of liver echotomography in Wilson’s disease during childhood. J Nucl Med Allied Sci 31:231–239
Zachoval R, Glaser C (1998) Images in hepatology. J Hepatol 29:489
Vogel W, Kathrein H, Dietze O, Judmaier G (1988) Sonography of the liver in Wilson’s disease. Sonographic studies of the liver in Wilson’s disease-significance for assessing prognosis? Ultraschall Med 9:270–273
Vogel W, Kathrein H, Dietze O, Judmaier G (1988) Ultrasonography in Wilson’s disease (letter). Ann Intern Med 108:769–770
Vogl TJ, Steiner S, Hammerstingl R, et al. (1994) MRT of the liver in Wilson’s disease. Rofo 160:40–45
Ko S, Lee T, Ng S, Lin J, Cheng Y (1998) Unusual liver MR findings of Wilson’s disease in an asymptomatic 2-year-old girl. Abdom Imag 23:56–59
Akhan O (2007) Imaging of diffuse liver disease. Eur J Radiol 61:1–2
Akpinar E, Akhan O (2007) Liver imaging findings of Wilson’s disease. Eur J Radiol 61:25–32
Akhan O, Akpinar E, Karcacltincaba M, et al. (2009) Imaging findings of liver involvement of Wilson’s disease. Eur J Radiol 69:147–155
Sutcliffe RP, Maguire DD, Muiesan P, et al. (2003) Liver transplantation for Wilson’s disease: long-term results and quality-of-life assessment. Transplantation 75:1003–1006
Geissler I, Heinemann K, Rohm S, Hauss J, Lamesch P (2003) Liver transplantation for hepatic and neurological Wilson’s disease. Transplant Proc 35:1445–1446
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Li, W., Zhao, X., Zhan, Q. et al. Unique CT imaging findings of liver in Wilson’s disease. Abdom Imaging 36, 69–73 (2011). https://doi.org/10.1007/s00261-010-9606-8
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00261-010-9606-8