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Paroxysmal nocturnal hemoglobinuria: complete resolution of an occluding inferior vena caval thrombus

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Abstract

Paroxysmal nocturnal hemoglobinuria is a rare acquired autoimmune disease, and is frequently associated with venous thrombosis. A patient who developed thrombotic occlusion of the inferior vena cava is described. Treatment with heparin and urokinase, followed by oral anticoagulant, was effective in resolving abdominal symptoms. The venous thrombosis resolved completely, but the patient died during treatment of aplastic anemia.

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Authors and Affiliations

  1. Second Department of Surgery, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo City, Yamanashi, 409-3898, Japan

    Shunya Shindo MD, Shinya Motohashi MD, Shigeaki Kaga MD, Hidenori Inoue MD & Masahiko Matsumoto MD

  2. Department of Hematology, Yamanashi Prefectural Central Hospital, Yamanashi, Japan

    Hiroo Shindo MD

Authors
  1. Shunya Shindo MD
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  2. Shinya Motohashi MD
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  3. Shigeaki Kaga MD
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  4. Hidenori Inoue MD
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  5. Masahiko Matsumoto MD
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  6. Hiroo Shindo MD
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Shindo, S., Motohashi, S., Kaga, S. et al. Paroxysmal nocturnal hemoglobinuria: complete resolution of an occluding inferior vena caval thrombus. Abdom Imaging 32, 754–757 (2007). https://doi.org/10.1007/s00261-007-9184-6

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  • DOI: https://doi.org/10.1007/s00261-007-9184-6

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