Skip to main content

Advertisement

SpringerLink
Log in

Pediatric Burkitt’s lymphoma: CT findings

  • Published:
Abdominal Imaging Aims and scope Submit manuscript

Abstract

Purpose

To review and analyze all CT scans of the cases of Burkitt’s lymphoma (BL) in children diagnosed in our institution.

Materials and methods

A retrospective analysis of 33 children with BL between the years 2003 and 2005 seen in our institution was undertaken. Twenty-nine male and four female patients from age 3 to 16 years (with a mean age 5.9 years) were reviewed.

Results

The gastrointestinal tract was involved in 19 patients (57.5%), kidneys in 9 (27.2%), peritoneum in 8 (24.2%), liver in 4 (12.1%), spleen in 3 (9%), adrenals in 3 (9%), and pancreas in 1 patient (3%). Extra-nodal head and neck involvement was seen in eight patients (24.2%). Bone involvement in four (12.1%), lung in three (9%), heart in two (6%), skin in two (6%), and testis in one (3%) of these patients. Abdominal lymph nodes were enlarged in 21 children (63.6%), while cervical lymph nodes were enlarged in 8 (24.2%).

Conclusion

CT proved to be an invaluable tool in the characterization of the disease processes in these children. In addition, it provided us with useful information about the anatomical distribution, patterns of involvement, as well as complications of BL.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.

Similar content being viewed by others

References

  1. Ardekian L, Rachmiel A, Rosen D, et al. (1999) Burkitt’s lymphoma of the oral cavity in Israel. J Craniomaxillofac Surg 27:294–297

    PubMed  CAS  Google Scholar 

  2. Burkitt D (1958) A sarcoma involving the jaws in African children. Br J Surg 46:218–223

    Article  PubMed  CAS  Google Scholar 

  3. O’Conor GT (1961) Malignant lymphoma in African children. Cancer 14:270–283

    Article  PubMed  CAS  Google Scholar 

  4. O’Conor TG, Davies JNP (1960) Malignant tumors in African children with special reference to malignant lymphoma. J Pediatr 56:226–535

    Google Scholar 

  5. Burkitt DP (1967) Burkitt’s lymphoma outside known endemic areas of Africa and New Guinea. Int J Cancer 2:562–565

    Article  PubMed  CAS  Google Scholar 

  6. Daldorff G (1965) Lymphoma of Brazilian children. JAMA 208:1365–1368

    Article  Google Scholar 

  7. O’Conor GT, Rappaport H, Smith EB (1965) Childhood lymphoma resembling Burkitt’s tumor in the United States. Cancer 18:411–417

    Article  PubMed  CAS  Google Scholar 

  8. Shapire J, Peylan-Ramu N (1998) Burkitt’s lymphoma. Oral Oncol 34:15–23

    Article  Google Scholar 

  9. Philip T (1985) Burkitt’s lymphoma in Europe. In: Lenoir G, O’Conor G, Olweny CLM, (eds). Burkitt’s lymphoma: a human cancer model. Lyon, IARC Scientific publications, pp 107–118

    Google Scholar 

  10. Ziegler JL, Beckstead JA, Volberding PA, et al. (1984) Non-Hodgkin’s lymphoma in 90 homosexual men. Relation to generalized lymphadenopathy and the acquired immunodeficiency syndrome. N Engl J Med 311:570–656

    Article  Google Scholar 

  11. Reed Dunnick N, Reaman GH, Head GL, et al. (1979) Radiographic manifestations of Burkitt’s lymphoma in American patients. AJR 132:1–6

    Google Scholar 

  12. Bureo E, Orlega JJ, Munoz A, et al. (1995) Bone marrow transplantation in 46 pediatric patients with non-Hodgkin’s lymphoma. Bone Marrow transplant 15:353–359

    PubMed  CAS  Google Scholar 

  13. Kearns DB, Smith RJH, Pitcock JK (1968) Burkitt’s lymphoma. Int J Pediatr Otorhinolaryngol 12:37–84

    Google Scholar 

  14. Stovroff MC, Coran AG, Hutchinson RJ (1991) The role of surgery in American Burkitt’s lymphoma in children. J Pediatr Surg 26:1235–1238

    Article  PubMed  CAS  Google Scholar 

  15. Cavdor AO, Yavuz G, Babacan E, et al. (1994) Burkitt’s lymphoma in Turkish children. Clinical viral (EBV) and molecular studies. Leuk lymphoma 14:232–330

    Google Scholar 

  16. Koniaris LG, Druges G, Katzman PL, et al. (2003) Management of GIT lymphoma. J Am coll surg 197:127–141

    Article  PubMed  Google Scholar 

  17. Reznek RH, Mootoo Samy I, Webb JAW, et al. (1990) CT in renal and perirenal lymphoma: further look. Clinc Radiol 42:233–238

    Article  CAS  Google Scholar 

  18. Chepuri NB, Strouse PJ, Yanik GA (2003) CT of renal lymphoma in children. AJR 18:429–431

    Google Scholar 

  19. Horis SC, Bosniak MA, Megibow AJ, et al. (1983) Correlation of CT and US in the evaluation of renal lymphoma. Urol Radiol 5:69–76

    Article  Google Scholar 

  20. Cohan RH, Dunnick NR, Leder RA, et al. (1990) CT of renal lymphoma, J Comp Assist Tomogr 14:933–938

    Article  CAS  Google Scholar 

  21. Heiken JP, Gold RP, Schnur MJ, et al. (1983) CT of renal lymphoma with US correlation. J Comput Assist Tomogr 7:245–250

    Article  PubMed  CAS  Google Scholar 

  22. Park KY, Yu J-S, Yoon S-W, et al. (2004) Burkitt’s lymphoma representing periportal infiltrating mass on CT. Yonsei Medical J 45:723–726

    Google Scholar 

  23. Banthia V, Jen A, Kacker A (2003) Sporadic Burkitt’s lymphoma of the head and neck in pediatric population, Int J Pediatr Otorhinolaryngnol 67:59–65

    Article  Google Scholar 

  24. Lewis WB, Perlman PW, Ilasi J (2000) Pediatric American Burkitt’s lymphoma of the sphenoid sinus. Otolaryngol Head Neck Surg 123:642–644

    Article  PubMed  CAS  Google Scholar 

  25. Huisman TAGM, Tschirch F, Schneider JFL, et al. (2003) Burkitt’s lymphoma with bilateral cavernous sinus and mediastinal involvement in a child. Pediatric Radiol 33:719–721

    Article  Google Scholar 

  26. Kalina P, Black K, Woldenberg R (1996) Burkitt’s lymphoma of skull base presenting as cavernous sinus syndrome in early childhood. Pediatric Radiol 26:416–417

    Article  CAS  Google Scholar 

  27. Delpassand ES, Kirkpatrick JB (1988) Cavernous sinus syndrome as the presentation of malignant lymphoma. Neurosurgery 23:501–504

    Article  PubMed  CAS  Google Scholar 

  28. Bergler-Klein J, Knoebl P, Kos T, et al. (2003) Myocardial involvement in a patient with Burkitt’s lymphoma mimicking hypertrophic cardiomyopathy. Am Soc Echocardiogr 16:1326–1330

    Article  Google Scholar 

Download references

Acknowledgments

The authors would like to thank Sue Kaste DO, MD, and Bassem I. Razzouk, MD, for their advice and kind editorial assistance.

Author information

Authors and Affiliations

  1. Diagnostic Radiology, King Hussein Cancer Center, Amman, Jordan

    Atheel A. Kamona, Maan A. El-Khatib, Maisa Y. Swaidan, Mohamed S. Jarar, Abdallah J. Suleiman, Hani M. Al Ali, Ahmed B. Basharaheel & Asem H. Mansour

Authors
  1. Atheel A. Kamona
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Maan A. El-Khatib
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Maisa Y. Swaidan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Mohamed S. Jarar
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Abdallah J. Suleiman
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Hani M. Al Ali
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Ahmed B. Basharaheel
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Asem H. Mansour
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Maisa Y. Swaidan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kamona, A.A., El-Khatib, M.A., Swaidan, M.Y. et al. Pediatric Burkitt’s lymphoma: CT findings. Abdom Imaging 32, 381–386 (2007). https://doi.org/10.1007/s00261-006-9069-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00261-006-9069-0

Keywords

Search

Navigation