Abstract
We report on two patients who underwent magnetic resonance imaging (MRI) as part of the evaluation of focal liver lesions. Both lesions had completely different MRI appearances, showing characteristics of benign and malignant liver lesions. Neither patient had clinical signs of endocrine hyperactivity, and both underwent subsequent liver resection. Histology showed neuroendocrine liver tumors in both patients; and because no primary tumor could be identified after careful search, the diagnosis of primary neureoendocrine tumor of the liver was established. Our observations suggest that primary neuroendocrine tumors of the liver may have a wide spectrum of appearances on MRI.
Similar content being viewed by others
References
JF Berger JP Laissy O Limot et al. (1996) ArticleTitleDifferentiation between multiple liver hemangiomas and liver metastases of gastrinomas: value of enhanced MRI. J Comput Assist Tomogr 20 349–355 Occurrence Handle10.1097/00004728-199605000-00003 Occurrence Handle1:STN:280:BymB3MjhvVU%3D Occurrence Handle8626888
GA Macdonald AJ Peduto (2000) ArticleTitleMagnetic resonance imaging (MRI) and diseases of the liver and biliary tract. Part 1. Basic principles, MRI in the assessment of diffuse and focal hepatic disease. J Gastroenterol Hepatol 15 980–991 Occurrence Handle10.1046/j.1440-1746.2000.02278.x Occurrence Handle1:STN:280:DC%2BD3M3jt1aqsg%3D%3D Occurrence Handle11059926
MP Debray O Geoffroy JP Laissy et al. (2001) ArticleTitleImaging appearances of metastases from neuroendocrine tumours of the pancreas. Br J Radiol 74 1065–1070 Occurrence Handle1:STN:280:DC%2BD3MnmtlKhsw%3D%3D Occurrence Handle11709476
M Pilichowska N Kimura A Ouchi et al. (1999) ArticleTitlePrimary hepatic carcinoid and neuroendocrine carcinoma: clinicopathological and immunohistochemical study of five cases. Pathol Int 49 318–324 Occurrence Handle10.1046/j.1440-1827.1999.00866.x Occurrence Handle1:STN:280:DyaK1M3ptF2ksQ%3D%3D Occurrence Handle10365851
K Takayasu Y Muramatsu M Sakamoto et al. (1992) ArticleTitleFindings in primary hepatic carcinoid tumor: US, CT, MRI, and angiography. J Comput Assist Tomogr 16 99–102 Occurrence Handle1:STN:280:By2C3crlsFA%3D Occurrence Handle1729316
E Solcia G Kloeppel LH. Sobin (2000) Histological typing of endocrine tumors Springer-Verlag New York
RI Ruckert JC Ruckert Y Dorffel et al. (1999) ArticleTitlePrimary hepatic neuroendocrine tumor: successful hepatectomy in two cases and review of the literature. Digestion 60 110–116 Occurrence Handle10.1159/000007635 Occurrence Handle1:STN:280:DyaK1M7ps1yrtw%3D%3D Occurrence Handle10095151
D Kehagias L Moulopoulos V Smirniotis et al. (1999) ArticleTitleImaging findings in primary carcinoid tumour of the liver with gastrin production. Br J Radiol 72 207–209 Occurrence Handle1:STN:280:DyaK1M3ptlCisg%3D%3D Occurrence Handle10365076
I Imaoka K Sugimura K Tamura (1993) ArticleTitleCase report: MR imaging of a carcinoid tumour of the liver. Clin Radiol 47 287–289 Occurrence Handle1:STN:280:ByyB28rntFE%3D Occurrence Handle8495581
Y Iimuro Y Deguchi Y Ueda et al. (2002) ArticleTitlePrimary hepatic carcinoid tumor with metachronous lymph node metastasis after long-term follow up. J Gastroenterol Hepatol 17 1119–1124 Occurrence Handle10.1046/j.1440-1746.2002.02663.x Occurrence Handle12201876
J Furrer A Hattenschwiler P Komminoth et al. (2001) ArticleTitleCarcinoid syndrome, acromegaly, and hypoglycemia due to an insulin-secreting neuroendocrine tumor of the liver. J Clin Endocrinol Metab 86 2227–2230 Occurrence Handle1:CAS:528:DC%2BD3MXjs1Omtb8%3D Occurrence Handle11344231
P Soyer K Tidjani JP Laissy et al. (1994) ArticleTitleDynamic Gd-DOTA-enhanced MR imaging of hepatic metastases from pancreatic neuroendocrine tumors. Eur J Radiol 18 180–184 Occurrence Handle10.1016/0720-048X(94)90331-X Occurrence Handle1:STN:280:ByqD2crmt10%3D Occurrence Handle7957287
ATRT Tjon JB Jansen TH Falke CB Lamers (1994) ArticleTitleImaging features of somatostatinoma: MR, CT, US, and angiography. J Comput Assist Tomogr 18 427–431 Occurrence Handle8188911
CM Sofka RC Semelka HB Marcos JT Woosley (1997) ArticleTitleMR imaging of metastatic pancreatic VIPoma. Magn Reson Imaging 15 1205–1208 Occurrence Handle10.1016/S0730-725X(97)00201-4 Occurrence Handle1:STN:280:DyaK1c%2FntVSrsg%3D%3D Occurrence Handle9408142
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
van der Hoef, M., Crook, D., Marincek, B. et al. Primary neuroendocrine tumors of the liver: MRI features in two cases . Abdom Imaging 29, 77–81 (2004). https://doi.org/10.1007/s00261-003-0064-4
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00261-003-0064-4