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Hepatic and splenic amyloidosis: dual-phase spiral CT findings


Although the liver and spleen are frequently involved in primary systemic amyloidosis, the clinical manifestations of hepatic and splenic involvement are usually mild and a dominant symptomatic hepatic presentation is uncommon. We report a case of a 51-year-old woman with giant hepatomegaly, hypertransaminasemia, increase in alkaline phosphatase, and ascites, in whom the findings of dual-phase spiral computed tomography suggested liver and splenic amyloidosis.

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Correspondence to P. P. Mainenti, L. D’Agostino, E. Soscia, M. Romano or M. Salvatore.

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Mainenti, ., D’Agostino, ., Soscia, . et al. Hepatic and splenic amyloidosis: dual-phase spiral CT findings. Abdom Imaging 28, 688–690 (2003).

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  • Amyloidosis
  • Computed tomography
  • Liver
  • Spleen.