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Contrast-enhanced dynamic ultrasonography of the liver: optimization of hepatic arterial phase in normal volunteers

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Abstract

Background: To optimize hepatic arterial phase timing in contrast-enhanced dynamic ultrasonography (US) of the liver.

Methods: Dynamic US was performed by using a microbubble-specific mode in 22 healthy volunteers after bolus injection of SH U 508A. Images were analyzed to determine whether hepatic arterial and portal venous phases could be temporally discriminated. Delay times to contrast enhancement at the hepatic artery (Aini) and portal vein (Pini) and the delay time until the signals between both vessels became inseparable (Aend) were determined.

Results: The hepatic arterial and portal venous phases could be temporally discriminated in all subjects. Aini, Pini, and Aend (mean ± standard deviation) were 11.0 ± 2.0, 14.8 ± 3.6, and 22.6 ± 5.1 s, respectively.

Conclusion: In hepatic contrast-enhanced dynamic US, hepatic arterial phase scanning should be commenced earlier than 11 s and terminated after 23 s postinjection.

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Authors and Affiliations

  1. Department of Radiology and the Institute of Radiation Medicine, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, 28, Yongon-dong, Chongno-gu Seoul 110-744, Korea

    K. H. Lee,  B. I. Choi,  K. W. Kim,  J. S. Kim,  H. J. Won,  J. K. Han,  S. H. Kim &  S. H. Park

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  1. K. H. Lee
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  2. B. I. Choi
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  3. K. W. Kim
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  4. J. S. Kim
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  5. H. J. Won
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  6. J. K. Han
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  7. S. H. Kim
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  8. S. H. Park
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Lee, ., Choi, ., Kim, . et al. Contrast-enhanced dynamic ultrasonography of the liver: optimization of hepatic arterial phase in normal volunteers. Abdom Imaging 28, 652–656 (2003). https://doi.org/10.1007/s00261-002-0092-5

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  • DOI: https://doi.org/10.1007/s00261-002-0092-5

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