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Letter to the editor regarding “The effect of long-acting somatostatin analogs on the uptake of [177Lu]Lu-HA-DOTATATE”

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References

  1. Veerman CHAM, Siebinga H, de Vries-Huizing DMV, Tesselaar MET, Hendrikx JJMA, Stokkel MPM, Aalbersberg EA. The effect of long-acting somatostatin analogues on the uptake of [(177)Lu]Lu-HA-DOTATATE. Eur J Nucl Med Mol Imaging. 2023;50:1434–41.

    Article  CAS  PubMed  Google Scholar 

  2. Zaknun JJ, Bodei L, Mueller-Brand J, Pavel ME, Baum RP, Horsch D, et al. The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours. Eur J Nucl Med Mol Imaging. 2013;40:800–16. https://doi.org/10.1007/s00259-012-2330-6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Dorr U, Wurm K, Horing E, Guzman G, Rath U, Bihl H. Diagnostic reliability of somatostatin receptor scintigraphy during continuous treatment with different somatostatin analogs. Hormone Metab Res. 1993;27:36–43.

    Google Scholar 

  4. Janson ET, Kalkner KM, Eriksson B, Westlin JE, Oberg K. Somatostatin receptor scintigraphy during treatment with lanreotide in patients with neuroendocrine tumors. Nucl Med Biol. 1999;26:877–82. https://doi.org/10.1016/s0969-8051(99)00059-1.

    Article  CAS  PubMed  Google Scholar 

  5. Haug AR, Rominger A, Mustafa M, Auernhammer C, Goke B, Schmidt GP, et al. Treatment with octreotide does not reduce tumor uptake of (68)Ga-DOTATATE as measured by PET/CT in patients with neuroendocrine tumors. J Nucl Med. 2011;52:1679–83. https://doi.org/10.2967/jnumed.111.089276.

    Article  CAS  PubMed  Google Scholar 

  6. Ayati N, Lee ST, Zakavi R, Pathmaraj K, Al-Qatawna L, Poon A, et al. Long-acting somatostatin analog therapy differentially alters (68)Ga-DOTATATE uptake in normal tissues compared with primary tumors and metastatic lesions. J Nucl Med. 2018;59:223–7. https://doi.org/10.2967/jnumed.117.192203.

    Article  CAS  PubMed  Google Scholar 

  7. Cherk MH, Kong G, Hicks RJ, Hofman MS. Changes in biodistribution on (68)Ga-DOTA-Octreotate PET/CT after long acting somatostatin analogue therapy in neuroendocrine tumour patients may result in pseudoprogression. Cancer Imaging. 2018;18:3. https://doi.org/10.1186/s40644-018-0136-x.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Aalbersberg EA, de Wit-van der Veen BJ, Versleijen MWJ, Saveur LJ, Valk GD, Tesselaar MET, et al. Influence of lanreotide on uptake of (68)Ga-DOTATATE in patients with neuroendocrine tumours: a prospective intra-patient evaluation. Eur J Nucl Med Mol Imaging. 2019;46:696–703. https://doi.org/10.1007/s00259-018-4117-x.

    Article  CAS  PubMed  Google Scholar 

  9. Galne A, Almquist H, Almquist M, Hindorf C, Ohlsson T, Nordenstrom E, et al. A prospective observational study to evaluate the effects of long-acting somatostatin analogs on (68)Ga-DOTATATE uptake in patients with neuroendocrine tumors. J Nucl Med. 2019;60:1717–23. https://doi.org/10.2967/jnumed.119.226332.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Li Y, Xu J, Xu X, Zhang J, Zhang Y. Long-acting octreotide treatment has no impact on tumor uptake of 99mTc-HYNIC-TOC in patients with neuroendocrine tumors. Nucl Med Commun. 2019;40:1005–10. https://doi.org/10.1097/MNM.0000000000001075.

    Article  CAS  PubMed  Google Scholar 

  11. Jahn U, Ilan E, Velikyan I, Fross-Baron K, Lubberink M, Sundin A. Receptor depletion and recovery in small-intestinal neuroendocrine tumors and normal tissues after administration of a single intravenous dose of octreotide measured by (68)Ga-DOTATOC PET/CT. EJNMMI Res. 2021;11:118. https://doi.org/10.1186/s13550-021-00860-0.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Bozkurt MF, Virgolini I, Balogova S, Beheshti M, Rubello D, Decristoforo C, et al. Guideline for PET/CT imaging of neuroendocrine neoplasms with (68)Ga-DOTA-conjugated somatostatin receptor targeting peptides and (18)F-DOPA. Eur J Nucl Med Mol Imaging. 2017;44:1588–601. https://doi.org/10.1007/s00259-017-3728-y.

    Article  CAS  PubMed  Google Scholar 

  13. Lodge MA, Solnes LB, Chaudhry MA, Wahl RL. Prospective within-patient assessment of the impact of an unlabeled octreotide pre-dose on the biodistribution and tumor uptake of Ga-68 DOTATOC as assessed by dynamic whole-body pet in patients with neuroendocrine tumors: implications for diagnosis and therapy. Molecul Imag Bio. 2021;23:766–74. https://doi.org/10.1007/s11307-021-01600-5.

    Article  CAS  Google Scholar 

  14. Hope TA, Allen-Auerbach M, Bodei L, Calais J, Dahlbom M, Dunnwald LK, et al. SNMMI procedure standard/EANM practice guideline for SSTR PET: imaging neuroendocrine tumors. J Nucl Med. 2023;64:204–10. https://doi.org/10.2967/jnumed.122.264860.

    Article  CAS  PubMed  Google Scholar 

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Funding

This work was supported by the National Natural Science Foundation of Sichuan Province (Grant No. 2022NSFSC1391) and the Post-Doctor Research Project, West China Hospital, Sichuan University (grant 2023HXBH075).

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Authors and Affiliations

  1. Department of Nuclear Medicine, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu, 610041, Sichuan, China

    Rang Wang, Linlin Guo & Guohua Shen

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  1. Rang Wang
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  2. Linlin Guo
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  3. Guohua Shen
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Correspondence to Guohua Shen.

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Wang, R., Guo, L. & Shen, G. Letter to the editor regarding “The effect of long-acting somatostatin analogs on the uptake of [177Lu]Lu-HA-DOTATATE”. Eur J Nucl Med Mol Imaging 51, 180–182 (2023). https://doi.org/10.1007/s00259-023-06375-1

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  • DOI: https://doi.org/10.1007/s00259-023-06375-1

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