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Improved resolution and sensitivity of [18F]MFBG PET compared with [123I]MIBG SPECT in a patient with a norepinephrine transporter–expressing tumour

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References

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Acknowledgements

Christophe M. Deroose is Senior Clinical Investigator at Research Foundation - Flanders (FWO).

Funding

This research was funded by the project from “Kom op tegen Kanker”: “PET/MR imaging of the norepinephrine transporter and somatostatin receptor in neural crest and neuroendocrine tumors for better radionuclide therapy selection” and received support from FWO (G0D8817N).

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Authors and Affiliations

  1. Nuclear Medicine, University Hospitals Leuven, UZ Leuven, Campus Gasthuisberg, Herestraat 49, BE-3000, Leuven, Belgium

    Elin Pauwels, Kristof Baete, Kim Serdons, Koen Van Laere & Christophe M. Deroose

  2. Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium

    Elin Pauwels, Kristof Baete, Kim Serdons, Koen Van Laere & Christophe M. Deroose

  3. Radiopharmaceutical Research, Department of Pharmacy and Pharmacology, KU Leuven, Leuven, Belgium

    Sofie Celen, Mathilde Vandamme, William Leysen & Guy Bormans

  4. Oncology, University Hospitals Leuven, Leuven, Belgium

    Oliver Bechter

  5. Endocrinology, University Hospitals Leuven, Leuven, Belgium

    Marie Bex

Authors
  1. Elin Pauwels
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  2. Sofie Celen
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  3. Mathilde Vandamme
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  4. William Leysen
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  5. Kristof Baete
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  6. Oliver Bechter
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  7. Marie Bex
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  8. Kim Serdons
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  9. Koen Van Laere
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  10. Guy Bormans
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  11. Christophe M. Deroose
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Corresponding author

Correspondence to Christophe M. Deroose.

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Conflict of interest

Koen Van Laere has performed consultancy services and contract research through KU Leuven for GE Healthcare, Merck, Janssen Pharmaceuticals, UCB, Syndesi Therapeutics, CuraSen, Celgene and Eikonizo. Guy Bormans has performed contract research through KU Leuven with Eikonizo, Merck, Celgene, Janssen Pharmaceuticals and UCB. Christophe M. Deroose has been a consultant through KU Leuven for Novartis, Terumo, AAA, Ipsen, Sirtex, Bayer outside the scope of the submitted work. There are no other conflicts of interest.

Ethical approval

All procedures performed in the study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (Ethische Commissie Onderzoek UZ/KU Leuven, S63142) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the prospective clinical study (NCT04258592), including the patient presented in this case report. A separate written consent from the patient was obtained for publication of the case report.

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Pauwels, E., Celen, S., Vandamme, M. et al. Improved resolution and sensitivity of [18F]MFBG PET compared with [123I]MIBG SPECT in a patient with a norepinephrine transporter–expressing tumour. Eur J Nucl Med Mol Imaging 48, 313–315 (2021). https://doi.org/10.1007/s00259-020-04830-x

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  • DOI: https://doi.org/10.1007/s00259-020-04830-x

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