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Comments on Eusebio et al.: Voxel-based analysis of whole-brain effects of age and gender on dopamine transporter SPECT imaging in healthy subjects

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References

  1. Eusebio A, Azulay JP, Ceccaldi M, Girard N, Mundler O, Guedj E. Voxel-based analysis of whole-brain effects of age and gender on dopamine transporter SPECT imaging in healthy subjects. Eur J Nucl Med Mol Imaging 2012;39:1778–1783. doi:10.1007/s00259-012-2207-8.

  2. Lavalaye J, Booij J, Reneman L, Habraken JB, van Royen EA. Effect of age and gender on dopamine transporter imaging with [123I]FP-CIT SPET in healthy volunteers. Eur J Nucl Med 2000;27:867–9.

    Article  PubMed  CAS  Google Scholar 

  3. van de Giessen E, Hesse S, Caan MWA, Zientek F, Dickson JC, Tossici-Bolt L, et al. No association between striatal dopamine transporter binding and body mass index: a multi-center European study in healthy volunteers. Neuroimage 2012. doi:10.1016/j.neuroimage.2012.09.011.

  4. Koopman KE, la Fleur SE, Fliers E, Serlie MJ, Booij J. Assessing the optimal time point for the measurement of extrastriatal serotonin transporter binding with 123I-FP-CIT SPECT in healthy, male subjects. J Nucl Med 2012;53:1087–90.

    Article  PubMed  CAS  Google Scholar 

  5. Booij J, de Jong J, de Bruin K, Knol R, de Win MM, van Eck-Smit BL. Quantification of striatal dopamine transporters with 123I-FP-CIT SPECT is influenced by the selective serotonin reuptake inhibitor paroxetine: a double-blind, placebo-controlled, crossover study in healthy control subjects. J Nucl Med 2007;48:359–66.

    PubMed  CAS  Google Scholar 

  6. Hesse S, Meyer PM, Strecker K, Barthel H, Wegner F, Oehlwein C, et al. Monoamine transporter availability in Parkinson’s disease patients with or without depression. Eur J Nucl Med Mol Imaging 2009;36:428–35.

    Article  PubMed  CAS  Google Scholar 

  7. Roselli F, Pisciotta NM, Pennelli M, Aniello MS, Gigante A, De Caro MF, et al. Midbrain SERT in degenerative parkinsonisms: a 123I-FP-CIT SPECT study. Mov Disord 2010;25:1853–9.

    Article  PubMed  Google Scholar 

  8. Abi-Dargham A, Gandelman MS, DeErausquin GA, Zea-Ponce Y, Zoghbi SS, Baldwin RM, et al. SPECT imaging of dopamine transporters in human brain with iodine-123-fluoroalkyl analogs of β-CIT. J Nucl Med 1996;37:1129–33.

    PubMed  CAS  Google Scholar 

  9. Scheffel U, Lever JR, Abraham P, Parham KR, Mathews WB, Kopajtic T, Carroll FI, et al. N-substituted phenyltropanes as in vivo binding ligands for rapid imaging studies of the dopamine transporter. Synapse 1997;25:345–9.

    Article  PubMed  CAS  Google Scholar 

  10. Booij J, Andringa G, Rijks LJ, Vermeulen RJ, De Bruin K, Boer GJ, et al. [123I]FP-CIT binds to the dopamine transporter as assessed by biodistribution studies in rats and SPECT studies in MPTP-lesioned monkeys. Synapse 1997;27:183–90.

    Article  PubMed  CAS  Google Scholar 

  11. Andringa G, Drukarch B, Bol JG, de Bruin K, Sorman K, Habraken JB, et al. Pinhole SPECT imaging of dopamine transporters correlates with dopamine transporter immunohistochemical analysis in the MPTP mouse model of Parkinson’s disease. Neuroimage 2005;26:1150–8.

    Article  PubMed  Google Scholar 

  12. Spiegel J, Hellwig D, Samnick S, Jost W, Möllers MO, Fassbender K, et al. Striatal FP-CIT uptake differs in the subtypes of early Parkinson’s disease. J Neural Transm 2007;114:331–5.

    Article  PubMed  CAS  Google Scholar 

  13. Hesse S, van de Giessen E, Zientek F, Varrone A, Tatsch K, Sabri O, Booij J. Association of serotonin transporter (SERT) availability and body mass index (BMI) in healthy Europeans. J Nucl Med 2012;53(Suppl 1):2062.

    Google Scholar 

  14. Lundkvist C, Halldin C, Swahn CG, Hall H, Karlsson P, Nakashima Y, Wang S, et al. [O-methyl-11C]beta-CIT-FP, a potential radioligand for quantitation of the dopamine transporter: preparation, autoradiography, metabolite studies, and positron emission tomography examinations. Nucl Med Biol 1995;22:905–13.

    Article  PubMed  CAS  Google Scholar 

  15. Lundkvist C, Halldin C, Ginovart N, Swahn CG, Farde L. [18F]β-CIT-FP is superior to [11C]β-CIT-FP for quantitation of the dopamine transporter. Nucl Med Biol 1997;24:621–7.

    Article  PubMed  CAS  Google Scholar 

  16. Erritzoe D, Frokjaer VG, Haahr MT, Kalbitzer J, Svarer C, Holst KK, et al. Cerebral serotonin transporter binding is inversely related to body mass index. Neuroimage 2010;52:284–9.

    Article  PubMed  CAS  Google Scholar 

  17. Jovanovic H, Lundberg J, Karlsson P, Cerin A, Saijo T, Varrone A, et al. Sex differences in the serotonin 1A receptor and serotonin transporter binding in the human brain measured by PET. Neuroimage 2008;39:1408–19.

    Article  PubMed  Google Scholar 

  18. Laruelle M, Slifstein M, Huang Y. Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography. Mol Imaging Biol 2003;5:363–75.

    Article  PubMed  Google Scholar 

  19. Booij J, Hemelaar TG, Speelman JD, de Bruin K, Janssen AG, van Royen EA. One-day protocol for imaging of the nigrostriatal dopaminergic pathway in Parkinson’s disease by [123I]FPCIT SPECT. J Nucl Med 1999;40:753–61.

    PubMed  CAS  Google Scholar 

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Booij, J., van de Giessen, E., Hesse, S. et al. Comments on Eusebio et al.: Voxel-based analysis of whole-brain effects of age and gender on dopamine transporter SPECT imaging in healthy subjects. Eur J Nucl Med Mol Imaging 40, 143–144 (2013). https://doi.org/10.1007/s00259-012-2267-9

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  • DOI: https://doi.org/10.1007/s00259-012-2267-9

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