References
Booij J, Tissingh G, Winogrodzka A, Boer GJ, Stoof JC, Wolters EC, Van Royen EA. Practical benefit of123I-FP-beta-CIT SPET in the demonstration of the dopaminergic deficit in Parkinson's disease. Eur J Nucl Med 1997; 24:68–71.
Walker Z, Costa DC, Ince P, Mc Keith IG, Katona CL. In-vivo demonstration of dopaminergic degeneration in dementia with Lewy bodies. Lancet 1999; 354:646–647.
Kung HF, Kim HJ, Kung MP, Meegalla SK, Plössl K, Lee H-K. Imaging of dopamine transporters in humans with technetium-99m TRODAT-1. Eur J Nucl Med 1996; 23:1527–1530.
Mozley LH, Gur RC, Mozley PD, Gur RE. Striatal dopamine transporters and cognitive functioning in healthy men and women. Am J Psychiatry 2001; 158:1492–1499.
Kushner SA, McElgin WT, Kung MP, Mozley PD, Plössl K, Meegalla SK, Mu M, Dresel S, Vessotskie JM, Lexow N, Kung HF. Kinetic modelling of99mTc TRODAT-1: a dopamine transporter imaging agent. J Nucl Med 1999; 40:150–158.
Plössl K, Kung M-P, Meegalla SK, Dresel S, Kushner SA, Mu M, Huang X-F, Mozley PD, Kung HF. [Tc-99m]M-TRODAT: an improved dopamine transporter imaging agent. J Nucl Med 1998; 39:6P.
Meegalla SK, Plössl K, Kung M-P, Chumpradit S, Stevenson DA, Kushner SA, McElgin WT, Mozley PD, Kung HF. Synthesis and characterization of technetium-99m-labeled tropanes as dopamine transporter-imaging agents. J Med Chem 1997; 40:9–17.
Cleynhens B, Vanbilloen H, Bormans G, de Groot T, Verbruggen A. Synthesis and isolation of the diastereomers of 4-tolyl-, 4-ethylphenyl- and 2,4-dimethylphenyl derivatives of99mTc-TRODAT-1. J Labelled Compd Radiopharm 2001; 44:S529–S531.
Acknowledgements
The authors thank Dr. H. Kung for the helpful discussions and for kindly agreeing to the performance of this study.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Maes, A., Vanbilloen, H., Cleynhens, B. et al. 99mTc-M-TRODAT is not superior to 99mTc-TRODAT-1 for the diagnosis of Parkinson's disease. Eur J Nucl Med Mol Imaging 30, 796–797 (2003). https://doi.org/10.1007/s00259-003-1125-1
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00259-003-1125-1