Skip to main content


Log in

Epithelioid hemangioendothelioma of bone

  • Published:
Skeletal Radiology Aims and scope Submit manuscript


 Neoplasms of bone can arise from any of the cellular elements that constitute osseous tissues. Although tumors of vascular origin are not uncommon, the vast majority are benign. A rare malignant vascular tumor – epithelioid hemangioendothelioma of bone – classifically affects young males and produces osteolytic lesions involving the cortex and cancellous bone of the lower extremities. We present a case with these findings, as well as such unusual findings as cervical spine instability and lesions affecting no fewer than 45 different bones. We conclude that epithelioid hemangioendo-thelioma should be investigated by skeletal survey because (1) osteolytic lesions involving more that 50% of the cortex present a serious risk for pathologic fracture and (2) the natural history of multicentric epithelioid hemangioendothelioma is more indolent than its solitary counterparts

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Author information

Authors and Affiliations


Rights and permissions

Reprints and permissions

About this article

Cite this article

Boutin, R., Spaeth, H., Mangalik, A. et al. Epithelioid hemangioendothelioma of bone. Skeletal Radiol 25, 391–395 (1996).

Download citation

  • Issue Date:

  • DOI: