Deep fibromatosis is a locally aggressive neoplasm commonly involving the extremities. Several authors have described imaging features and complications associated with deep fibromatosis. We present the case of a 33-year-old man who presented with a right gluteal fibrous mass identified on magnetic resonance imaging (MRI), which was associated with a pseudoaneurysm originating from the right superior gluteal artery on serial follow-up with MRI and computed tomography. No intervention was done, and after conservative management, spontaneous thrombosis of the pseudoaneurysm was developed. Such imaging finding is the first report of a spontaneous development of pseudoaneurysm caused by deep fibromatosis, which could be a life-threatening condition and should be considered when dealing with deep fibromatosis and deciding on the appropriate treatment.
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Trautmann M, Rehkämper J, Gevensleben H, et al. Novel pathogenic alterations in pediatric and adult desmoid-type fibromatosis – a systematic analysis of 204 cases. Sci Rep. 2020;10:3368.
Master S, Mangla A, Puckett Y, Shah C. Desmoid tumor [Internet]. Ncbi.nlm.nih.gov. 2022. Available from: https://www.ncbi.nlm.nih.gov/books/NBK459231/. Accessed 25 September 2022
Nieuwenhuis M, Casparie M, Mathus-Vliegen L, Dekkers O, Hogendoorn P, Vasen H. A nation-wide study comparing sporadic and familial adenomatous polyposis-related desmoid-type fibromatoses. Int J Cancer. 2010;129(1):256–61.
De Wever I, Cin P, Fletcher C, et al. Cytogenetic, clinical, and morphologic correlations in 78 cases of fibromatosis: a report from the CHAMP Study Group. Mod Pathol. 2000;13(10):1080–5.
Desmoid Tumor - NORD (National Organization for Rare Disorders) [Internet]. NORD (National Organization for Rare Disorders). 2022. Available from: https://rarediseases.org/rare-diseases/desmoid-tumor/. Accessed 25 September 2022
Long N, Gounder M, Crago A, Chou A, Panicek D. Pseudoaneurysm within a desmoid tumor in an extremity: report of 2 cases. Skeletal Radiol. 2021;50(10):2107–15.
Cuomo P, Scoccianti G, Schiavo A et al. Extra-abdominal desmoid tumor fibromatosis: a multicenter EMSOS study. BMC Cancer. 2021;21(1). https://doi.org/10.1186/s12885-021-08189-6
Schlemmer M. Desmoid tumors and deep fibromatoses. Hematol/Oncol Clin North America. 2005;19(3):565–71.
Escobar C, Munker R, Thomas J, Li B, Burton G. Update on desmoid tumors. Ann Oncol. 2012;23(3):562–9.
McDonald E, Yi E, Wenger D. Extraabdominal desmoid-type fibromatosis. Radiographics. 2008;28(3):901–6.
Stoeckle E, Coindre J, Longy M, et al. A critical analysis of treatment strategies in desmoid tumours: a review of a series of 106 cases. Eur J Surg Oncol (EJSO). 2009;35(2):129–34.
Devata S, Chugh R. Desmoid tumors. Hematol Oncol Clin North Am. 2013;27(5):989–1005.
Molloy AP, Hutchinson B, O’Toole GC. Extra-abdominal desmoid tumours: a review of the literature. Sarcoma. 2012;2012:1–9.
Sundaram M, McGuire M, Schajowicz F. Soft-tissue masses: histologic basis for decreased signal (short T2) on T2-weighted MR images. Am J Roentgenol. 1987;148(6):1247–50.
Murphey M, Ruble C, Tyszko S, Zbojniewicz A, Potter B, Miettinen M. Musculoskeletal fibromatoses: radiologic-pathologic correlation. Radiographics. 2009;29(7):2143–83.
Ganeshan D, Amini B, Nikolaidis P, Assing M, Vikram R. current update on desmoid fibromatosis. J Comput Assist Tomogr. 2019;43(1):29–38.
Briand S, Barbier O, Biau D, et al. Wait-and-see policy as a first-line management for extra-abdominal desmoid tumors. J Bone Joint Surg. 2014;96(8):631–8.
Zheng C, Zhou Y, Wang Y, Luo Y, Tu C, Min L. the activity and safety of anlotinib for patients with extremity desmoid fibromatosis: a retrospective study in a single institution. Drug Des Dev Ther. 2020;14:3941–50.
Alman B, Attia S, Baumgarten C, et al. The management of desmoid tumours: a joint global consensus-based guideline approach for adult and paediatric patients. Eur J Cancer. 2020;127:96–107.
Gounder M, Mahoney M, Van Tine B, et al. Sorafenib for advanced and refractory desmoid tumors. N Engl J Med. 2018;379(25):2417–28.
Schmitz J, Schmit G, Atwell T, et al. Percutaneous cryoablation of extraabdominal desmoid tumors: a 10-year experience. Am J Roentgenol. 2016;207(1):190–5.
Redifer Tremblay K, Lea W, Neilson J, King D, Tutton S. Percutaneous cryoablation for the treatment of extra-abdominal desmoid tumors. J Surg Oncol. 2019;120(3):366–75.
Ilaslan H, Schils J, Joyce M, Marks K, Sundaram M. Radiofrequency ablation: another treatment option for local control of desmoid tumors. Skeletal Radiol. 2009;39(2):169–73.
Ghanouni P, Dobrotwir A, Bazzocchi A, et al. Magnetic resonance-guided focused ultrasound treatment of extra-abdominal desmoid tumors: a retrospective multicenter study. Eur Radiol. 2016;27(2):732–40.
Cassidy M, Lefkowitz R, Long N, et al. Association of MRI T2 signal intensity with desmoid tumor progression during active observation. Ann Surg. 2020;271(4):748–55.
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Alsayegh, H., Alzaid, T., Khawaji, A. et al. Aggressive gluteal fibromatosis: a rare case associated with spontaneous superior gluteal artery pseudoaneurysm. Skeletal Radiol 52, 1593–1598 (2023). https://doi.org/10.1007/s00256-022-04263-7