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Diagnostic contribution of contrast-enhanced 3D MR imaging of peripheral nerve pathology

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Abstract

Objective

To assess the diagnostic contribution of contrast-enhanced 3D STIR (ce3D-SS) high-resolution magnetic resonance (MR) imaging of peripheral nerve pathology relative to conventional 2D sequences.

Materials and methods

In this IRB-approved retrospective study, two radiologists reviewed 60 MR neurography studies with nerve pathology findings. The diagnostic contribution of ce3D-SS imaging was scored on a 4-point Likert scale (1 = no additional information, 2 = supports interpretation, 3 = moderate additional information, and 4 = diagnosis not possible without ce3D-SS). Image quality, nerve visualization, and detection of nerve pathology were also assessed for both standard 2D neurography and ce3D-SS sequences utilizing a 3-point Likert scale. Descriptive statistics are reported.

Results

The diagnostic contribution score for ce3D-SS imaging was 2.25 for the brachial plexus, 1.50 for extremities, and 1.75 for the lumbosacral plexus. For brachial plexus, the mean consensus scores for image quality, nerve visualization, and detection of nerve pathology were 2.55, 2.5, and 2.55 for 2D and 2.35, 2.45, and 2.45 for 3D. For extremities, the mean consensus scores for image quality, nerve visualization, and detection of nerve pathology were 2.60, 2.80, and 2.70 for 2D and 1.8, 2.20, and 2.10 for 3D. For lumbosacral plexus, the mean consensus scores for image quality, nerve visualization, and detection of nerve pathology were 2.45, 2.75, and 2.65 for 2D and 2.0, 2.45, and 2.25 for 3D.

Conclusion

Overall, our study supports the potential application of ce3D-SS imaging for MRN of the brachial plexus but suggests that 2D MRN protocols are sufficient for MRN of the extremities and lumbosacral plexus.

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Authors and Affiliations

  1. Department of Radiology, Northwestern University Feinberg School of Medicine, 420 E Superior St, Chicago, IL, 60611, USA

    Swati Deshmukh & Jonathan Samet

  2. Northwestern University Feinberg School of Medicine, 420 E Superior St, Chicago, IL, 60611, USA

    Kyle Tegtmeyer

  3. University of Illinois At Urbana-Champaign, 601 E John St, Champaign, IL, 61820, USA

    Mounisha Kovour

  4. Department of Radiology, Johns Hopkins Hospital, 1800 Orleans St, Baltimore, MD, 21287, USA

    Shivani Ahlawat

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  1. Swati Deshmukh
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  2. Kyle Tegtmeyer
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  3. Mounisha Kovour
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  4. Shivani Ahlawat
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  5. Jonathan Samet
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Deshmukh, S., Tegtmeyer, K., Kovour, M. et al. Diagnostic contribution of contrast-enhanced 3D MR imaging of peripheral nerve pathology. Skeletal Radiol 50, 2509–2518 (2021). https://doi.org/10.1007/s00256-021-03816-6

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  • DOI: https://doi.org/10.1007/s00256-021-03816-6

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