Skip to main content

Advertisement

Log in

Anterior cervical discectomy and fusion: review and update for radiologists

  • Review Article
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

Abstract

Objectives

The goals of this article are to describe the various types of interbody grafts and anterior cervical plating systems, techniques for optimizing evaluation of cervical spine metallic implants on CT and MR imaging, expected appearance and complications of ACDF on postoperative imaging and imaging assessment of fusion. Optimization for optimizing metal induced artifacts.

Conclusion

Currently, ACDF is the most commonly performed surgical procedure for degenerative cervical spine disease. Interbody fusion is performed with bone grafts or interbody spacers, and may be supplemented with anterior cervical plating. Compressive pathologies at the vertebral body level may be addressed by simultaneous corpectomy. Postoperatively, imaging plays an integral role in routine screening of asymptomatic individuals, fusion assessment and evaluation of complications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12

Similar content being viewed by others

References

  1. Cepoiu-Martin M, Faris P, Lorenzetti D, Prefontaine E, Noseworthy T, Sutherland L. Artificial cervical disc arthroplasty: a systematic review. Spine (Phila Pa 1976). 2011;36(25):E1623–33.

    Article  Google Scholar 

  2. Korinth MC. Treatment of cervical degenerative disc disease: current status and trends. Zentralbl Neurochir. 2008;69(3):113–24.

    Article  CAS  PubMed  Google Scholar 

  3. Willson MC, Ross JS. Postoperative spine complications. Neuroimaging Clin N Am. 2014;24(2):305–26.

    Article  PubMed  Google Scholar 

  4. Chau AMT, Mobbs RJ. Bone graft substitutes in anterior cervical discectomy and fusion. Eur Spine J. 2009;18:449–64.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Emery SE. Cervical spondylotic myelopathy: diagnosis and treatment. J Am Acad Orthop Surg. 2001;9(6):376–88.

    Article  CAS  PubMed  Google Scholar 

  6. Silber JS, Anderson DG, Daffner SD, Brislin BT, Leland JM, Hilibrand AS, et al. Donor site morbidity after anterior iliac crest bone harvest for single-level anterior cervical discectomy and fusion. Spine. 2004;28:134–9.

    Article  Google Scholar 

  7. Ryken TC, Heary RF, Matz PG, Anderson PA, Groff MW, Holly LT, et al. Joint section on disorders of the spine and peripheral nerves of the American Association of Neurological Surgeons and Congress of Neurological Surgeons. Techniques for cervical interbody grafting. J Neurosurg Spine. 2009:203–20.

  8. Beaman FD, Bancroft LW, Peterson JJ, Kransdorf MJ, Menke DM, DeOrio JK. Imaging characteristics of bone graft materials. Radiographics. 2006;26(2):373–88.

    Article  PubMed  Google Scholar 

  9. An HS, Simpson JM, Glover JM, Stephany J. Comparison between allograft plus demineralized bone matrix versus autograft in anterior cervical fusion: a prospective multicenter study. Spine. 1995;20(20):2211–6.

    Article  CAS  PubMed  Google Scholar 

  10. Gore DR. Technique of cervical interbody fusion. Clin Orthop Relat Res. 1984;188:191–5.

    Google Scholar 

  11. Suchomel P, Barsa P, Buchvald P, Svobodnik A, Vanickova E. Autologous versus allogenic bone grafts in instrumented anterior cervical discectomy and fusion: a prospective study with respect to bone union pattern. Eur Spine J. 2004;13(6):510–5.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Rutherford EE, Tarplett LJ, Davies EM, Harley JM, King LJ. Lumbar spine fusion and stabilization: hardware, techniques, and imaging appearances. Radiographics. 2007;27(6):1737–49.

    Article  PubMed  Google Scholar 

  13. Peolsson A, Vavruch L, Hedlund R. Long-term randomized comparison between a carbon fibre cage and the Cloward procedure in the cervical spine. Eur Spine J. 2006;16:173–8.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Ryu SI, Mitchell M, Kim DH. A prospective randomized study comparing a cervical carbon fiber cage to the smith-Robinson technique with allograft and plating: up to 24 months follow-up. Eur Spine J. 2006;15(2):157–64.

    Article  PubMed  Google Scholar 

  15. Cahill DW, Martin GJ, Hajjar MV, Sonstein W, Gaham LB, Engelman RW. Suitabilty of bioresorbable cages for anterior cervical fusion. J Neurosurg (Spine). 2003;98:195–201.

    Article  Google Scholar 

  16. Madawi AA, Powell M, Crockard HA. Biocompatible osteoconductive polymer versus iliac graft: a prospective comparative study for the evaluation of fusion pattern after anterior cervical discectomy. Spine. 1996;S21:2123–30.

    Article  Google Scholar 

  17. Kandziora F, Bail H, Schmidmaier G, Schollmeier G, Scholz M, Knispel C, et al. Bone morphogenetic protein-2 application by a poly(D,L-lactide)-coated interbody cage: in vivo results of a new carrier for growth factors. J Neurosurg. 2002;97(1 Suppl):40–8.

    CAS  PubMed  Google Scholar 

  18. Stein MI, Nayak AN, Gaskins RB 3rd, Cabezas AF, Santoni BG, Castellvi AE. Biomechanics of an integrated interbody device versus ACDF anterior locking plate in a single-level cervical spine fusion construct. Spine J. 2014;14(1):128–36.

    Article  PubMed  Google Scholar 

  19. Zhou J, Xia Q, Dong J, Li X, Zhou X, Fang T, et al. Comparison of stand-alone polyetheretherketone cages and iliac crest autografts for the treatment of cervical degenerative disc diseases. Acta Neurochir. 2011;153(1):115–22.

    Article  PubMed  Google Scholar 

  20. Nouh MR. Spinal fusion-hardware construct: basic concepts and imaging review. World J Radiol. 2012;4(5):193–207.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Haid RW, Foley KT, Rodts GE, Barnes B. The cervical spine study group anterior cervical plate nomenclature. Neurosurg Focus. 2002;12(1):E15.

    Article  PubMed  Google Scholar 

  22. Wang JC, McDonough PW, Endow K, Kanim LE, Delamarter RB. The effect of cervical plating on single-level anterior cervical discectomy and fusion. J Spinal Disord. 1999;12:467–71.

    Article  CAS  PubMed  Google Scholar 

  23. Samartzis D, Shen FH, Lyon C, Phillips M, Goldberg EJ, An HS. Does rigid instrumentation increase the fusion rate in one-level anterior cervical discectomy and fusion? Spine. 2004;4:636–43.

    Article  Google Scholar 

  24. Grob D, Peyer JV, Dvorak J. The use of plate fixation in anterior surgery of the degenerative cervical spine: a comparative prospective clinical study. Eur Spine J. 2001;10:408–13.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Wang JC, McDonough PW, Endow KK, Delamarter RB. Increased fusion rates with cervical plating for two-level anterior cervical discectomy and fusion. Spine. 2000;25:41–5.

    Article  CAS  PubMed  Google Scholar 

  26. Wang JC, McDonough PW, Kanim LE, Endow KK, Delamarter RB. Increased fusion rates with cervical plating for three-level anterior cervical discectomy and fusion. Spine. 2001;26:643–7.

    Article  CAS  PubMed  Google Scholar 

  27. Samartzis D, Shen FH, Matthews DK, Yoon ST, Goldberg EJ, An HS. Comparison of allograft to autograft in multilevel anterior cervical discectomy and fusion with rigid plate fixation. Spine J. 2003;3:451–9.

    Article  PubMed  Google Scholar 

  28. Griffith SL, Zogbi SW, Guyer RD, Shelokov AP, Contiliano JH, Geiger JM. Biomechanical comparison of anterior instrumentation for the cervical spine. J Spinal Disord. 1995;8:429–38.

    Article  CAS  PubMed  Google Scholar 

  29. Grubb MR, Currier BL, Shih JS, Bonin V, Grabowski JJ, Chao EY. Biomechanical evaluation of anterior cervical spine stabilization. Spine. 1998;23:886–92.

    Article  CAS  PubMed  Google Scholar 

  30. Rhee JM, Riew KD. Dynamic anterior cervical plates. J Am Acad Orthop Surg. 2007;15(11):640–6.

    Article  PubMed  Google Scholar 

  31. Campos RR, Botelho RV. Systematic review of the effect of dynamic fixation systems compared with rigid fixation in the anterior cervical spine. Eur Spine J. 2014;23(2):298–304.

    Article  PubMed  Google Scholar 

  32. Schroeder GD, Kepler CK, Hollern DA, et al. The effect of dynamic versus static plating systems on fusion rates and complications in 1-level and/or 2-level anterior cervical discectomy and fusion: a systematic review. Clin Spine Surg. 2017;30(1):20–6.

    PubMed  Google Scholar 

  33. Rhee JM, Park JB, Yang JY, Riew DK. Indications and techniques for anterior cervical plating. Neurol India. 2005;53(4):433–9.

    Article  PubMed  Google Scholar 

  34. Macdonald RL, Fehlings MG, Tator CH, Lozano A, Fleming JR, Gentili F, et al. Multilevel anterior cervical corpectomy and fibular allograft fusion for cervical myelopathy. J Neurosurg. 1997;86:990–7.

    Article  CAS  PubMed  Google Scholar 

  35. Kabir SM, Alabi J, Rezajooi K, Casey AT. Anterior cervical corpectomy: review and comparison of results using titanium mesh cages and carbon fibre reinforced polymer cages. Br J Neurosurg. 2010;24(5):542–6.

    Article  PubMed  Google Scholar 

  36. Kasliwal MK, O’Toole JE. Clinical experience using polyetheretherketone (PEEK) intervertebral structural cage for anterior cervical corpectomy and fusion. J Clin Neurosci. 2014;21(2):217–20.

    Article  CAS  PubMed  Google Scholar 

  37. Vaccaro AR, Falatyn SP, Scuderi GJ, Eismont FJ, McGuire RA, Singh K, et al. Early failure of long segment anterior cervical plate fixation. J Spinal Disord. 1998;11:410–5.

    CAS  PubMed  Google Scholar 

  38. lizzard DJ, Hustedt JW, Bohl DD, Telles CJ, Grauer JN. Routine anteroposterior radiographs have limited utility for patients after anterior cervical decompression and fusion. Spine (Phila Pa 1976). 2012;37(22):1904–8.

    Article  Google Scholar 

  39. Bohl DD, Hustedt JW, Blizzard DJ, Badrinath R, Grauer JN. Routine imaging for anterior cervical decompression and fusion procedures: a survey study establishing current practice patterns. Orthopedics. 2012;35(7):e1068–72.

    Article  PubMed  Google Scholar 

  40. acsearch.acr.org [Internet]. Reston, VA:ARC. American College of Radiology: ACR appropriateness criteria®: chronic neck pain (last review date: 2013). [cited 2017 Jul 9]. Available from: https://acsearch.acr.org/docs/69426/Narrative/

  41. Gupta A, Subhas N, Primak AN, Nittka M, Liu K. Metal artifact reduction: standard and advanced magnetic resonance and computed tomography techniques. Radiol Clin N Am. 2015;53(3):531–47.

    Article  PubMed  Google Scholar 

  42. Becce F, Ben Salah Y, Verdun FR, et al. Computed tomography of the cervical spine: comparison of image quality between a standard-dose and a low-dose protocol using filtered back-projection and iterative reconstruct. Skelet Radiol. 2013;42(7):937–45.

    Article  Google Scholar 

  43. Ross JS. Magnetic resonance imaging of the postoperative spine. Semin Musculoskelet Radiol. 2000;4(3):281–91.

    Article  CAS  PubMed  Google Scholar 

  44. Jungmann PM, Agten CA, Pfirrmann CW, Sutter R. Advances in MRI around metal. J Magn Reson Imaging. 2017;Mar 25.

  45. Ren C, Song Y, Xue Y, Yang X. Mid- to long-term outcomes after cervical disc arthroplasty compared with anterior discectomy and fusion: a systematic review and meta-analysis of randomized controlled trials. Eur Spine J. 2014;23(5):1115–23.

    Article  PubMed  Google Scholar 

  46. Alvin MD, Abbott EE, Lubelski D, Kuhns B, Nowacki AS, Steinmetz MP, et al. Cervical arthroplasty: a critical review of the literature. Spine. 2014;14(9):2231–45.

    Article  Google Scholar 

  47. Venu V, Vertinsky AT, Malfair D, Chew JB, Shewchuk J, Heran MK, et al. Plain radiograph assessment of spinal hardware. Semin Musculoskelet Radiol. 2011;15(2):151–62.

    Article  PubMed  Google Scholar 

  48. Smucker JD, Rhee JM, Singh K, Yoon ST, Heller JG. Increased swelling complications associated with off-label usage of rhBMP-2 in the anterior cervical spine. Spine (Phila Pa 1976). 2006;31(24):2813–9.

    Article  Google Scholar 

  49. rhBMP-2 [Infuse] - North American Spine Society (12/4/2014). https://www.spine.org/Documents/PolicyPractice/CoverageRecommendations/rhBMP.pdf. Accessed 01/20/2017.

  50. Selby MD, Clark SR, Hall DJ, Freeman BJ. Radiologic assessment of spinal fusion. J Am Acad Orthop Surg. 2012;20(11):694–703.

    PubMed  Google Scholar 

  51. Carragee EJ, Hurwitz EL, Weiner BK. A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned. Spine J. 2011;11(6):471–91.

    Article  PubMed  Google Scholar 

  52. Slone RM, MacMillan M, Montgomery WJ. Spinal fixation: part 3, complications of spinal instrumentation. Radiographics. 1993;13(4):797–816.

    Article  CAS  PubMed  Google Scholar 

  53. Young PM, Berquist TH, Bancroft LW, Peterson JJ. Complications of spinal instrumentation. Radiographics. 2007;27(3):775–89.

    Article  PubMed  Google Scholar 

  54. Etebar S, Cahill DW. Risk factors for adjacent-segment failure following lumbar fixation with rigid instrumentation for degenerative instability. J Neurosurg. 1999;90(2 Suppl):163–9.

    CAS  PubMed  Google Scholar 

  55. Schlegel JD, Smith JA, Schleusener RL. Lumbar motion segment pathology adjacent to thoracolumbar, lumbar, and lumbosacral fusions. Spine (Phila Pa 1976). 1996;21(8):970–81.

    Article  CAS  Google Scholar 

  56. Lawrence BD, Hilibrand AS, Brodt ED, Dettori JR, Brodke DS. Predicting the risk of adjacent segment pathology in the cervical spine: a systematic review. Spine (Phila Pa 1976). 2012;37(22 Suppl):S52–64.

    Article  Google Scholar 

  57. Raizman NM, O’Brien JR, Poehling-Monaghan KL, Pseudarthrosis YWD. Of the spine. J Am Acad Orthop Surg. 2009;17(8):494–503.

    Article  PubMed  Google Scholar 

  58. Buchowski JM, Liu G, Bunmaprasert T, Rose PS, Riew KD. Anterior cervical fusion assessment: surgical exploration versus radiographic evaluation. Spine (Phila Pa 1976). 2008;33(11):1185–91.

    Article  Google Scholar 

  59. Fischgrund JS, Mackay M, Herkowitz HN, Brower R, Montgomery DM, Kurz LT. 1997 Volvo award winner in clinical studies. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation. Spine (Phila Pa 1976). 1997;22(24):2807–12.

    Article  CAS  Google Scholar 

  60. Herkowitz HN, Kurz LT. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective study comparing decompression with decompression and intertransverse process arthrodesis. J Bone Joint Surg Am. 1991;73(6):802–8.

    Article  CAS  PubMed  Google Scholar 

  61. Kornblum MB, Fischgrund JS, Herkowitz HN, Abraham DA, Berkower DL, Ditkoff JS. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective long-term study comparing fusion and pseudarthrosis. Spine (Phila Pa 1976). 2004;29(7):726–33; discussion 733–4

    Article  Google Scholar 

  62. Phillips FM, Carlson G, Emery SE, Bohlman HH. Anterior cervical pseudarthrosis: natural history and treatment. Spine (Phila Pa 1976). 1997;22(14):1585–9.

    Article  CAS  Google Scholar 

  63. Gruskay JA, Webb ML, Grauer JN. Methods of evaluating lumbar and cervical fusion. Spine J. 2014;14(3):531–9.

    Article  PubMed  Google Scholar 

  64. Andrews CL. Evaluation of the postoperative spine: spinal instrumentation and fusion. Semin Musculoskelet Radiol. 2000;4(3):259–79.

    Article  CAS  PubMed  Google Scholar 

  65. Hilibrand AS, Dina TS. The use of diagnostic imaging to assess spinal arthrodesis. Orthop Clin North Am. 1998;29(4):591–601.

    Article  CAS  PubMed  Google Scholar 

  66. Tuli SK, Chen P, Eichler ME, Woodard EJ. Reliability of radiologic assessment of fusion: cervical fibular allograft model. Spine (Phila Pa 1976). 2004;29(8):856–60.

    Article  Google Scholar 

  67. McAfee PC, Boden SD, Brantigan JW, Fraser RD, Kuslich SD, Oxland TR, et al. Symposium: a critical discrepancy—a criteria of successful arthrodesis following interbody spinal fusions. Spine (Phila Pa 1976). 2001;26(3):320–34.

    Article  CAS  Google Scholar 

  68. Ploumis A, Mehbod A, Garvey T, Gilbert T, Transfeldt E, Wood K. Prospective assessment of cervical fusion status: plain radiographs versus CT-scan. Acta Orthop Belg. 2006;72(3):342–6.

    PubMed  Google Scholar 

  69. Ghiselli G, Wharton N, Hipp JA, Wong DA, Jatana S. Prospective analysis of imaging prediction of pseudarthrosis after anterior cervical discectomy and fusion: computed tomography versus flexion-extension motion analysis with intraoperative correlation. Spine (Phila Pa 1976). 2011;36(6):463–8.

    Article  Google Scholar 

  70. Cannada LK, Scherping SC, Yoo JU, Jones PK, Emery SE. Pseudoarthrosis of the cervical spine: a comparison of radiographic diagnostic measures. Spine (Phila Pa 1976). 2003;28(1):46–51.

    Article  Google Scholar 

  71. Fassett DR, Apfelbaum RI, Hipp JA. Comparison of fusion assessment techniques: computer-assisted versus manual measurements. J Neurosurg Spine. 2008;8(6):544–7.

    Article  PubMed  Google Scholar 

  72. Rothman SL, Glenn WV Jr. CT evaluation of interbody fusion. Clin Orthop Relat Res. 1985; Mar;(193):47–56.

  73. Fogel GR, Toohey JS, Neidre A, Brantigan JW. Fusion assessment of posterior lumbar interbody fusion using radiolucent cages: X-ray films and helical computed tomography scans compared with surgical exploration of fusion. Spine J. 2007;8(4):570–7.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kimia Khalatbari Kani.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kani, K.K., Chew, F.S. Anterior cervical discectomy and fusion: review and update for radiologists. Skeletal Radiol 47, 7–17 (2018). https://doi.org/10.1007/s00256-017-2798-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00256-017-2798-z

Keywords

Navigation