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Chordoma arising from benign multifocal notochordal tumors

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This case reports a 25-year-old woman initially diagnosed with adjacent benign notochordal cell tumors (BNCTs) of L3 and L4 based on needle biopsy of L3 and stable imaging over a 3-year period who was ultimately found to have a chordoma arising from a BNCT at L3. It illustrates the potential relationship between benign and malignant notochordal tumors and the difficulty in distinguishing them by clinical, radiological, and even histopathological means.

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The authors wish to acknowledge the contributions of Ivy John, MD, for assistance in preparation of the original histopathology pictures and of Daniel Rosenthal, MD for his assistance in reviewing the radiological aspects of the manuscript.

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Correspondence to Timothy A. Damron.

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Arain, A., Hornicek, F.J., Schwab, J.H. et al. Chordoma arising from benign multifocal notochordal tumors. Skeletal Radiol 46, 1745–1752 (2017).

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